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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 33

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A phase II study of a urokinase-derived peptide (A6) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube, or primary peritoneal carcinoma: a Gynecologic Oncology Group study.
Gold MA, Brady WE, Lankes HA, Rose PG, Kelley JL, De Geest K, Crispens MA, Resnick KE, Howell SB
(2012) Gynecol Oncol 125: 635-9
MeSH Terms: Adult, Aged, Carcinoma, Ovarian Epithelial, Disease-Free Survival, Fallopian Tube Neoplasms, Female, Humans, Hyaluronan Receptors, Middle Aged, Neoplasm Recurrence, Local, Neoplasms, Glandular and Epithelial, Ovarian Neoplasms, Peptide Fragments, Peritoneal Neoplasms, Urokinase-Type Plasminogen Activator
Added March 10, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
In vivo formation of a glutathione conjugate derived from thalidomide in humanized uPA-NOG mice.
Yamazaki H, Suemizu H, Igaya S, Shimizu M, Shibata N, Nakamura M, Chowdhury G, Guengerich FP
(2011) Chem Res Toxicol 24: 287-9
MeSH Terms: Animals, Aryl Hydrocarbon Hydroxylases, Glutathione, Interleukin Receptor Common gamma Subunit, Liver, Mice, Mice, Transgenic, Microsomes, Liver, Models, Animal, Oxidation-Reduction, Thalidomide, Urokinase-Type Plasminogen Activator
Added March 26, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Antimetastatic role of Smad4 signaling in colorectal cancer.
Zhang B, Halder SK, Kashikar ND, Cho YJ, Datta A, Gorden DL, Datta PK
(2010) Gastroenterology 138: 969-80.e1-3
MeSH Terms: Adenocarcinoma, Animals, Antineoplastic Agents, Cadherins, Cell Line, Tumor, Cell Movement, Cell Proliferation, Colorectal Neoplasms, Female, Humans, Liver Neoplasms, Matrix Metalloproteinase 9, Mice, Mice, Inbred C57BL, Mice, Nude, NM23 Nucleoside Diphosphate Kinases, Neoplasm Invasiveness, Protein Kinase Inhibitors, Pyrazoles, Pyrroles, Receptors, Transforming Growth Factor beta, Signal Transduction, Smad4 Protein, Time Factors, Transfection, Transforming Growth Factor beta1, Urokinase-Type Plasminogen Activator
Added March 5, 2014
1 Communities
1 Members
0 Resources
27 MeSH Terms
Single-chain urokinase in empyema induced by Pasturella multocida.
Idell S, Jun Na M, Liao H, Gazar AE, Drake W, Lane KB, Koenig K, Komissarov A, Tucker T, Light RW
(2009) Exp Lung Res 35: 665-81
MeSH Terms: Animals, Empyema, Pleural, Exudates and Transudates, Fibrinolysis, Inflammation, Pasteurella multocida, Pleura, Rabbits, Treatment Outcome, Urokinase-Type Plasminogen Activator
Added May 27, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
A novel signaling pathway: fibroblast nicotinic receptor alpha1 binds urokinase and promotes renal fibrosis.
Zhang G, Kernan KA, Thomas A, Collins S, Song Y, Li L, Zhu W, Leboeuf RC, Eddy AA
(2009) J Biol Chem 284: 29050-64
MeSH Terms: Animals, Cell Membrane, Dose-Response Relationship, Drug, Fibroblasts, Fibrosis, Kidney, Kidney Diseases, Mass Spectrometry, Mice, Mice, Inbred C57BL, Nicotinic Antagonists, Protein Binding, Receptors, Nicotinic, Signal Transduction, Tubocurarine, Urokinase-Type Plasminogen Activator
Added February 3, 2012
0 Communities
1 Members
0 Resources
16 MeSH Terms
Serine proteases, inhibitors and receptors in renal fibrosis.
Eddy AA
(2009) Thromb Haemost 101: 656-64
MeSH Terms: Animals, Cell Movement, Chronic Disease, Fibrinolysin, Fibroblasts, Fibrosis, Humans, Kidney, Kidney Diseases, Kininogens, Low Density Lipoprotein Receptor-Related Protein-1, Macrophages, Membrane Glycoproteins, Nephritis, Plasminogen Activator Inhibitor 1, Receptors, Cell Surface, Receptors, Urokinase Plasminogen Activator, Serine Endopeptidases, Serpins, Signal Transduction, Tissue Plasminogen Activator, Urokinase-Type Plasminogen Activator, Vitronectin
Added February 3, 2012
0 Communities
1 Members
0 Resources
23 MeSH Terms
Urokinase and its receptors in chronic kidney disease.
Zhang G, Eddy AA
(2008) Front Biosci 13: 5462-78
MeSH Terms: Animals, Chronic Disease, Disease Models, Animal, Humans, Kidney Diseases, Kidney Failure, Chronic, Kinetics, Mice, Receptors, Cell Surface, Receptors, Urokinase Plasminogen Activator, Urokinase-Type Plasminogen Activator
Added February 3, 2012
0 Communities
1 Members
0 Resources
11 MeSH Terms
Endogenous urokinase lacks antifibrotic activity during progressive renal injury.
Yamaguchi I, Lopez-Guisa JM, Cai X, Collins SJ, Okamura DM, Eddy AA
(2007) Am J Physiol Renal Physiol 293: F12-9
MeSH Terms: Animals, Blotting, Western, Collagen, Disease Progression, Fibrin, Fibroblasts, Fibrosis, Genotype, Hepatocyte Growth Factor, Kidney, Kidney Diseases, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Peptide Hydrolases, Phenotype, Phosphorylation, Plasminogen Activators, RNA, Messenger, Ureteral Obstruction, Urokinase-Type Plasminogen Activator
Added February 3, 2012
0 Communities
1 Members
0 Resources
22 MeSH Terms
Smad4-dependent regulation of urokinase plasminogen activator secretion and RNA stability associated with invasiveness by autocrine and paracrine transforming growth factor-beta.
Shiou SR, Datta PK, Dhawan P, Law BK, Yingling JM, Dixon DA, Beauchamp RD
(2006) J Biol Chem 281: 33971-81
MeSH Terms: Autocrine Communication, Blotting, Northern, Breast Neoplasms, Cell Membrane, Cell Proliferation, Collagen, Drug Combinations, Female, Genes, Dominant, Humans, Immunoblotting, Laminin, Matrix Metalloproteinase 9, Neoplasm Invasiveness, Paracrine Communication, Plasminogen Activator Inhibitor 1, Proteoglycans, RNA Stability, Receptors, Transforming Growth Factor beta, Smad4 Protein, Transforming Growth Factor beta, Tumor Cells, Cultured, Urokinase-Type Plasminogen Activator
Added June 14, 2013
1 Communities
2 Members
0 Resources
23 MeSH Terms
Plasminogen activator inhibitor-1 deficiency has renal benefits but some adverse systemic consequences in diabetic mice.
Collins SJ, Alexander SL, Lopez-Guisa JM, Cai X, Maruvada R, Chua SC, Zhang G, Okamura DM, Matsuo S, Eddy AA
(2006) Nephron Exp Nephrol 104: e23-34
MeSH Terms: Animals, Blood Glucose, Cholesterol, Diabetes Mellitus, Experimental, Diabetic Nephropathies, Extracellular Matrix, Female, Kidney, Male, Mice, Mice, Inbred Strains, Plasminogen Activator Inhibitor 1, Urokinase-Type Plasminogen Activator
Added February 3, 2012
0 Communities
1 Members
0 Resources
13 MeSH Terms