Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 24

Publication Record

Connections

A tRNA processing enzyme is a key regulator of the mitochondrial unfolded protein response.
Held JP, Feng G, Saunders BR, Pereira CV, Burkewitz K, Patel MR
(2022) Elife 11:
MeSH Terms: Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Mitochondria, Transcription Factors, Unfolded Protein Response
Added June 6, 2022
0 Communities
1 Members
0 Resources
MeSH Terms
Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP.
Byndloss MX, Tsai AY, Walker GT, Miller CN, Young BM, English BC, Seyffert N, Kerrinnes T, de Jong MF, Atluri VL, Winter MG, Celli J, Tsolis RM
(2019) mBio 10:
MeSH Terms: Animals, Brucella abortus, Cell Death, Endoplasmic Reticulum Stress, Female, Mice, Mice, Inbred C57BL, Nod1 Signaling Adaptor Protein, Nod2 Signaling Adaptor Protein, Placenta, Pregnancy, Transcription Factor CHOP, Trophoblasts, Type IV Secretion Systems, Unfolded Protein Response
Added March 30, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain.
Chopra S, Giovanelli P, Alvarado-Vazquez PA, Alonso S, Song M, Sandoval TA, Chae CS, Tan C, Fonseca MM, Gutierrez S, Jimenez L, Subbaramaiah K, Iwawaki T, Kingsley PJ, Marnett LJ, Kossenkov AV, Crespo MS, Dannenberg AJ, Glimcher LH, Romero-Sandoval EA, Cubillos-Ruiz JR
(2019) Science 365:
MeSH Terms: Animals, Cells, Cultured, Cyclooxygenase 2, Dinoprostone, Endoribonucleases, Humans, Leukocytes, Mice, Mice, Inbred C57BL, Myeloid Cells, Pain, Postoperative, Promoter Regions, Genetic, Prostaglandin-E Synthases, Protein Serine-Threonine Kinases, Signal Transduction, Unfolded Protein Response, Visceral Pain, X-Box Binding Protein 1
Added March 12, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether.
Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P
(2019) Elife 8:
MeSH Terms: ATP-Binding Cassette Transporters, Activating Transcription Factor 6, CRISPR-Cas Systems, Endoplasmic Reticulum, HEK293 Cells, Hep G2 Cells, Humans, Organelles, Peroxisomes, Phenotype, Protein Binding, Small Molecule Libraries, Unfolded Protein Response
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Quantitative Interactome Proteomics Reveals a Molecular Basis for ATF6-Dependent Regulation of a Destabilized Amyloidogenic Protein.
Plate L, Rius B, Nguyen B, Genereux JC, Kelly JW, Wiseman RL
(2019) Cell Chem Biol 26: 913-925.e4
MeSH Terms: Activating Transcription Factor 6, Amyloidogenic Proteins, Amyloidosis, Endoplasmic Reticulum, Endoplasmic Reticulum Stress, HEK293 Cells, Humans, Molecular Chaperones, Proteomics, Transcription Factors, Unfolded Protein Response
Added March 3, 2020
0 Communities
1 Members
0 Resources
11 MeSH Terms
Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation Using Targeted RNA Sequencing.
Grandjean JMD, Plate L, Morimoto RI, Bollong MJ, Powers ET, Wiseman RL
(2019) ACS Chem Biol 14: 784-795
MeSH Terms: Animals, HEK293 Cells, Heat Shock Transcription Factors, Humans, Mice, NF-E2 Transcription Factor, Oxidative Stress, Proteostasis, Sequence Analysis, RNA, Signal Transduction, Unfolded Protein Response
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis.
Blackwood EA, Azizi K, Thuerauf DJ, Paxman RJ, Plate L, Kelly JW, Wiseman RL, Glembotski CC
(2019) Nat Commun 10: 187
MeSH Terms: Activating Transcription Factor 6, Animals, Animals, Newborn, Cells, Cultured, Cerebral Infarction, Disease Models, Animal, Endoplasmic Reticulum, Female, Heart Ventricles, Humans, Kidney, Kidney Diseases, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Myocardial Infarction, Myocytes, Cardiac, Primary Cell Culture, Protective Agents, Proteostasis, Rats, Reperfusion Injury, Treatment Outcome, Unfolded Protein Response
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins.
Paxman R, Plate L, Blackwood EA, Glembotski C, Powers ET, Wiseman RL, Kelly JW
(2018) Elife 7:
MeSH Terms: Activating Transcription Factor 6, Amides, Endoplasmic Reticulum, Endoplasmic Reticulum Stress, HEK293 Cells, Humans, Phenylpropionates, Prodrugs, Signal Transduction, Small Molecule Libraries, Unfolded Protein Response
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
The unfolded protein response regulator ATF6 promotes mesodermal differentiation.
Kroeger H, Grimsey N, Paxman R, Chiang WC, Plate L, Jones Y, Shaw PX, Trejo J, Tsang SH, Powers E, Kelly JW, Wiseman RL, Lin JH
(2018) Sci Signal 11:
MeSH Terms: Activating Transcription Factor 6, Animals, Cell Differentiation, Cell Line, Endoplasmic Reticulum, Endoplasmic Reticulum Stress, Gene Expression, Humans, Induced Pluripotent Stem Cells, Mesoderm, Mutation, Signal Transduction, Small Molecule Libraries, Unfolded Protein Response
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Endoplasmic reticulum stress in the pathogenesis of fibrotic disease.
Kropski JA, Blackwell TS
(2018) J Clin Invest 128: 64-73
MeSH Terms: Animals, Apoptosis, Endoplasmic Reticulum Stress, Fibrosis, Humans, Inflammation, Macrophages, Molecular Chaperones, Myofibroblasts, Signal Transduction, Unfolded Protein Response
Added March 21, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms