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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 17

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The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
Fischer K, Fenzl A, Liu D, Dyar KA, Kleinert M, Brielmeier M, Clemmensen C, Fedl A, Finan B, Gessner A, Jastroch M, Huang J, Keipert S, Klingenspor M, Brüning JC, Kneilling M, Maier FC, Othman AE, Pichler BJ, Pramme-Steinwachs I, Sachs S, Scheideler A, Thaiss WM, Uhlenhaut H, Ussar S, Woods SC, Zorn J, Stemmer K, Collins S, Diaz-Meco M, Moscat J, Tschöp MH, Müller TD
(2020) Nat Commun 11: 2306
MeSH Terms: Activating Transcription Factor 2, Adipogenesis, Adipose Tissue, Brown, Adipose Tissue, White, Animals, Cell Nucleus, Magnetic Resonance Imaging, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Obesity, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Positron Emission Tomography Computed Tomography, Protein Binding, Sequestosome-1 Protein, Uncoupling Protein 1, p38 Mitogen-Activated Protein Kinases
Added July 22, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
Cardiac natriuretic peptides promote adipose 'browning' through mTOR complex-1.
Liu D, Ceddia RP, Collins S
(2018) Mol Metab 9: 192-198
MeSH Terms: Adipose Tissue, Brown, Animals, Atrial Natriuretic Factor, Cells, Cultured, Cyclic GMP-Dependent Protein Kinases, Female, HEK293 Cells, Humans, Male, Mechanistic Target of Rapamycin Complex 1, Mice, Mice, Inbred C57BL, Mitochondria, Signal Transduction, Uncoupling Protein 1
Added September 25, 2018
0 Communities
2 Members
0 Resources
15 MeSH Terms
Pyruvate induces torpor in obese mice.
Soto M, Orliaguet L, Reyzer ML, Manier ML, Caprioli RM, Kahn CR
(2018) Proc Natl Acad Sci U S A 115: 810-815
MeSH Terms: Adenosine, Adipose Tissue, Brown, Animals, Brain, Insulin Resistance, Male, Mice, Inbred C57BL, Mice, Obese, Obesity, Pyruvic Acid, Torpor, Uncoupling Protein 1
Added March 22, 2018
0 Communities
1 Members
0 Resources
12 MeSH Terms
Second messenger signaling mechanisms of the brown adipocyte thermogenic program: an integrative perspective.
Shi F, Collins S
(2017) Horm Mol Biol Clin Investig 31:
MeSH Terms: Adipocytes, Beige, Adipocytes, Brown, Animals, Cyclic AMP-Dependent Protein Kinases, Cyclic GMP-Dependent Protein Kinases, Energy Metabolism, Gene Expression Regulation, Humans, Intracellular Space, Mechanistic Target of Rapamycin Complex 1, MicroRNAs, Natriuretic Agents, RNA, Long Noncoding, Receptors, Adrenergic, beta, Second Messenger Systems, Signal Transduction, Thermogenesis, Uncoupling Protein 1
Added September 26, 2018
0 Communities
2 Members
0 Resources
MeSH Terms
Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning.
Liu D, Bordicchia M, Zhang C, Fang H, Wei W, Li JL, Guilherme A, Guntur K, Czech MP, Collins S
(2016) J Clin Invest 126: 1704-16
MeSH Terms: 3T3-L1 Cells, Adaptor Proteins, Signal Transducing, Adipose Tissue, Brown, Adipose Tissue, White, Animals, Cyclic AMP-Dependent Protein Kinases, HEK293 Cells, Humans, Insulin, Mechanistic Target of Rapamycin Complex 1, Mice, Mice, Knockout, Multiprotein Complexes, Receptors, Adrenergic, beta, Regulatory-Associated Protein of mTOR, Ribosomal Protein S6 Kinases, 70-kDa, Ribosomal Protein S6 Kinases, 90-kDa, Signal Transduction, TOR Serine-Threonine Kinases, Uncoupling Protein 1
Added July 22, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Measuring respiratory activity of adipocytes and adipose tissues in real time.
Bugge A, Dib L, Collins S
(2014) Methods Enzymol 538: 233-47
MeSH Terms: Adipocytes, Adipose Tissue, Animals, Cell Line, Cell Respiration, Cells, Cultured, Energy Metabolism, Humans, Ion Channels, Mice, Mitochondria, Mitochondrial Proteins, Oxidation-Reduction, Oxygen Consumption, Uncoupling Protein 1
Added July 22, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Reversal of type 1 diabetes in mice by brown adipose tissue transplant.
Gunawardana SC, Piston DW
(2012) Diabetes 61: 674-82
MeSH Terms: Adipose Tissue, Brown, Animals, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 1, Female, Glucose, Homeostasis, Insulin, Interleukin-6, Ion Channels, Mice, Mice, Inbred C57BL, Mitochondrial Proteins, Receptor, Insulin, Streptozocin, Tumor Necrosis Factor-alpha, Uncoupling Protein 1, Weight Gain
Added December 5, 2013
2 Communities
2 Members
0 Resources
18 MeSH Terms
Ablation of ghrelin receptor reduces adiposity and improves insulin sensitivity during aging by regulating fat metabolism in white and brown adipose tissues.
Lin L, Saha PK, Ma X, Henshaw IO, Shao L, Chang BH, Buras ED, Tong Q, Chan L, McGuinness OP, Sun Y
(2011) Aging Cell 10: 996-1010
MeSH Terms: Adipose Tissue, Brown, Adipose Tissue, White, Adiposity, Aging, Animals, Diabetes Mellitus, Type 2, Eating, Energy Metabolism, Gene Expression Regulation, Ghrelin, Humans, Insulin Resistance, Ion Channels, Lipid Metabolism, Male, Mice, Mice, Knockout, Mitochondrial Proteins, Obesity, Receptors, Ghrelin, Signal Transduction, Thermogenesis, Uncoupling Protein 1
Added December 5, 2013
2 Communities
1 Members
0 Resources
23 MeSH Terms
Rat diaphragm mitochondria have lower intrinsic respiratory rates than mitochondria in limb muscles.
Garcia-Cazarin ML, Gamboa JL, Andrade FH
(2011) Am J Physiol Regul Integr Comp Physiol 300: R1311-5
MeSH Terms: Animals, Cell Respiration, Diaphragm, Extremities, Ion Channels, Male, Mitochondria, Muscle, Mitochondrial Proteins, Models, Animal, Muscle, Skeletal, Oxygen Consumption, Rats, Rats, Sprague-Dawley, Respiratory Muscles, Uncoupling Protein 1, Voltage-Dependent Anion Channel 1
Added April 25, 2016
0 Communities
1 Members
0 Resources
16 MeSH Terms
Orphan nuclear receptor NOR-1 enhances 3',5'-cyclic adenosine 5'-monophosphate-dependent uncoupling protein-1 gene transcription.
Kumar N, Liu D, Wang H, Robidoux J, Collins S
(2008) Mol Endocrinol 22: 1057-64
MeSH Terms: 3T3-L1 Cells, Adipose Tissue, Brown, Adipose Tissue, White, Animals, COS Cells, Cell Line, Chlorocebus aethiops, Chromatin Immunoprecipitation, Cyclic AMP, DNA-Binding Proteins, Electrophoretic Mobility Shift Assay, Humans, Immunoblotting, Ion Channels, Mice, Mice, Inbred BALB C, Mitochondrial Proteins, Nuclear Receptor Subfamily 4, Group A, Member 1, Nuclear Receptor Subfamily 4, Group A, Member 2, Protein Binding, Receptors, Cytoplasmic and Nuclear, Receptors, Steroid, Reverse Transcriptase Polymerase Chain Reaction, Transcription Factors, Transcription, Genetic, Uncoupling Protein 1
Added July 22, 2020
0 Communities
1 Members
0 Resources
MeSH Terms