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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 67

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The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling.
Shen C, Nayak A, Neitzel LR, Adams AA, Silver-Isenstadt M, Sawyer LM, Benchabane H, Wang H, Bunnag N, Li B, Wynn DT, Yang F, Garcia-Contreras M, Williams CH, Dakshanamurthy S, Hong CC, Ayad NG, Capobianco AJ, Ahmed Y, Lee E, Robbins DJ
(2021) Nat Commun 12: 5263
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Casein Kinase Ialpha, Drosophila Proteins, Drosophila melanogaster, Embryo, Nonmammalian, Evolution, Molecular, HEK293 Cells, Humans, Immunologic Factors, Lenalidomide, Mice, Organoids, Peptide Hydrolases, Ubiquitin-Protein Ligases, Ubiquitination, Wnt Signaling Pathway, Zebrafish, Zebrafish Proteins
Added September 11, 2021
0 Communities
1 Members
0 Resources
19 MeSH Terms
Bacterial CagA protein compromises tumor suppressor mechanisms in gastric epithelial cells.
Palrasu M, Zaika E, El-Rifai W, Garcia-Buitrago M, Piazuelo MB, Wilson KT, Peek RM, Zaika AI
(2020) J Clin Invest 130: 2422-2434
MeSH Terms: Antigens, Bacterial, Apoptosis Regulatory Proteins, Bacterial Proteins, Epithelial Cells, Gastric Mucosa, HCT116 Cells, Helicobacter pylori, Humans, Neoplasm Proteins, Proteolysis, Stomach Neoplasms, Ubiquitination, X-Linked Inhibitor of Apoptosis Protein
Added April 7, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
Spatiotemporal regulation of the Dma1-mediated mitotic checkpoint coordinates mitosis with cytokinesis.
Cullati SN, Gould KL
(2019) Curr Genet 65: 663-668
MeSH Terms: Cell Cycle Checkpoints, Cell Cycle Proteins, Cytokinesis, Mitosis, Phosphorylation, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Spatio-Temporal Analysis, Ubiquitination
Added April 10, 2019
0 Communities
1 Members
0 Resources
9 MeSH Terms
Myeloid-Specific Deletion of Epsins 1 and 2 Reduces Atherosclerosis by Preventing LRP-1 Downregulation.
Brophy ML, Dong Y, Tao H, Yancey PG, Song K, Zhang K, Wen A, Wu H, Lee Y, Malovichko MV, Sithu SD, Wong S, Yu L, Kocher O, Bischoff J, Srivastava S, Linton MF, Ley K, Chen H
(2019) Circ Res 124: e6-e19
MeSH Terms: Adaptor Proteins, Vesicular Transport, Animals, Apolipoproteins E, Atherosclerosis, Cells, Cultured, Down-Regulation, Gene Deletion, HEK293 Cells, Humans, Low Density Lipoprotein Receptor-Related Protein-1, Macrophages, Mice, Myeloid Cells, RAW 264.7 Cells, Receptors, LDL, Tumor Suppressor Proteins, Ubiquitination
Added April 10, 2019
0 Communities
1 Members
0 Resources
17 MeSH Terms
Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types.
Ge Z, Leighton JS, Wang Y, Peng X, Chen Z, Chen H, Sun Y, Yao F, Li J, Zhang H, Liu J, Shriver CD, Hu H, Cancer Genome Atlas Research Network, Piwnica-Worms H, Ma L, Liang H
(2018) Cell Rep 23: 213-226.e3
MeSH Terms: Cell Line, Tumor, Gene Expression Regulation, Neoplastic, Genome, Human, Genomics, Humans, Metabolic Networks and Pathways, Neoplasms, Oncogene Proteins, Ubiquitination
Added October 30, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer.
Bhuripanyo K, Wang Y, Liu X, Zhou L, Liu R, Duong D, Zhao B, Bi Y, Zhou H, Chen G, Seyfried NT, Chazin WJ, Kiyokawa H, Yin J
(2018) Sci Adv 4: e1701393
MeSH Terms: Amino Acid Sequence, Bacteriophages, Biocatalysis, Cyclin-Dependent Kinase 4, Endoplasmic Reticulum Stress, HEK293 Cells, Humans, Mutant Proteins, Mutation, Peptides, Proteolysis, Reproducibility of Results, Signal Transduction, Substrate Specificity, Tumor Suppressor Protein p53, Tumor Suppressor Proteins, Ubiquitin, Ubiquitin-Protein Ligase Complexes, Ubiquitin-Protein Ligases, Ubiquitination
Added March 24, 2018
0 Communities
1 Members
0 Resources
20 MeSH Terms
Suppressed ubiquitination of Nrf2 by p47 contributes to Nrf2 activation.
Ha Kim K, Sadikot RT, Yeon Lee J, Jeong HS, Oh YK, Blackwell TS, Joo M
(2017) Free Radic Biol Med 113: 48-58
MeSH Terms: Animals, Disease Models, Animal, HEK293 Cells, Humans, Kelch-Like ECH-Associated Protein 1, Lipopolysaccharides, Mice, NADPH Oxidases, NF-E2-Related Factor 2, Pneumonia, RAW 264.7 Cells, Reactive Oxygen Species, Signal Transduction, Ubiquitination
Added March 21, 2018
0 Communities
1 Members
0 Resources
14 MeSH Terms
SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer.
Lu W, Liu S, Li B, Xie Y, Izban MG, Ballard BR, Sathyanarayana SA, Adunyah SE, Matusik RJ, Chen Z
(2017) Oncogene 36: 1364-1373
MeSH Terms: Animals, Cell Line, Tumor, Disease Models, Animal, Enhancer of Zeste Homolog 2 Protein, Gene Knockout Techniques, Histones, Humans, Lysine, Male, Mice, PTEN Phosphohydrolase, Prostate, Prostatic Neoplasms, Protein Stability, S-Phase Kinase-Associated Proteins, TNF Receptor-Associated Factor 6, Tumor Suppressor Protein p53, Ubiquitination
Added April 18, 2017
0 Communities
1 Members
0 Resources
18 MeSH Terms
Interaction of Gcn4 with target gene chromatin is modulated by proteasome function.
Howard GC, Tansey WP
(2016) Mol Biol Cell 27: 2735-41
MeSH Terms: Adenosine Triphosphatases, Basic-Leucine Zipper Transcription Factors, Cell Cycle Proteins, Chromatin, DNA-Binding Proteins, Molecular Chaperones, Proteasome Endopeptidase Complex, Proteolysis, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Transcription Factors, Transcriptional Activation, Ubiquitin, Ubiquitination, Valosin Containing Protein
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
SOCS2 Balances Metabolic and Restorative Requirements during Liver Regeneration.
Masuzaki R, Zhao S, Valerius MT, Tsugawa D, Oya Y, Ray KC, Karp SJ
(2016) J Biol Chem 291: 3346-58
MeSH Terms: Animals, Cell Proliferation, Cells, Cultured, Gene Expression Regulation, Growth Hormone, Hepatectomy, Immunohistochemistry, Insulin-Like Growth Factor I, Liver, Liver Regeneration, Male, Mice, Inbred C57BL, Mice, Knockout, Pituitary Gland, Protein Transport, Proteolysis, Receptors, Somatotropin, Suppressor of Cytokine Signaling Proteins, Ubiquitination
Added April 11, 2016
0 Communities
1 Members
0 Resources
19 MeSH Terms