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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 19

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Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer.
Bhuripanyo K, Wang Y, Liu X, Zhou L, Liu R, Duong D, Zhao B, Bi Y, Zhou H, Chen G, Seyfried NT, Chazin WJ, Kiyokawa H, Yin J
(2018) Sci Adv 4: e1701393
MeSH Terms: Amino Acid Sequence, Bacteriophages, Biocatalysis, Cyclin-Dependent Kinase 4, Endoplasmic Reticulum Stress, HEK293 Cells, Humans, Mutant Proteins, Mutation, Peptides, Proteolysis, Reproducibility of Results, Signal Transduction, Substrate Specificity, Tumor Suppressor Protein p53, Tumor Suppressor Proteins, Ubiquitin, Ubiquitin-Protein Ligase Complexes, Ubiquitin-Protein Ligases, Ubiquitination
Added March 24, 2018
0 Communities
1 Members
0 Resources
20 MeSH Terms
Establishment of novel in vitro mouse chief cell and SPEM cultures identifies MAL2 as a marker of metaplasia in the stomach.
Weis VG, Petersen CP, Mills JC, Tuma PL, Whitehead RH, Goldenring JR
(2014) Am J Physiol Gastrointest Liver Physiol 307: G777-92
MeSH Terms: Animals, Biomarkers, Cells, Cultured, Chief Cells, Gastric, Gastric Mucosa, Intercellular Signaling Peptides and Proteins, Metaplasia, Mice, Myelin and Lymphocyte-Associated Proteolipid Proteins, Nuclear Proteins, Pepsinogen C, Peptides, Proteins, Repressor Proteins, Stomach, Ubiquitin-Protein Ligase Complexes, WAP Four-Disulfide Core Domain Protein 2, rab3 GTP-Binding Proteins
Added February 12, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
The anaphase promoting complex contributes to the degradation of the S. cerevisiae telomerase recruitment subunit Est1p.
Ferguson JL, Chao WC, Lee E, Friedman KL
(2013) PLoS One 8: e55055
MeSH Terms: Amino Acid Sequence, Anaphase-Promoting Complex-Cyclosome, Animals, Cdh1 Proteins, G1 Phase, Mutation, Protein Stability, Proteolysis, Recombinant Proteins, S Phase, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Telomerase, Ubiquitin-Protein Ligase Complexes, Ubiquitination
Added March 5, 2014
0 Communities
2 Members
0 Resources
15 MeSH Terms
State of the APC/C: organization, function, and structure.
McLean JR, Chaix D, Ohi MD, Gould KL
(2011) Crit Rev Biochem Mol Biol 46: 118-36
MeSH Terms: Anaphase-Promoting Complex-Cyclosome, Animals, Catalysis, Cell Cycle Proteins, Cell Nucleus, Humans, Meiosis, Microscopy, Electron, Mitosis, Models, Biological, Spindle Apparatus, Ubiquitin-Protein Ligase Complexes, Ubiquitin-Protein Ligases
Added March 5, 2014
0 Communities
3 Members
0 Resources
13 MeSH Terms
Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1.
Ohi MD, Feoktistova A, Ren L, Yip C, Cheng Y, Chen JS, Yoon HJ, Wall JS, Huang Z, Penczek PA, Gould KL, Walz T
(2007) Mol Cell 28: 871-85
MeSH Terms: Anaphase-Promoting Complex-Cyclosome, Cdc20 Proteins, Cell Cycle Proteins, Chromatography, Affinity, Cryoelectron Microscopy, Immunoblotting, Mitosis, Models, Molecular, Mutagenesis, Site-Directed, Mutation, Protein Conformation, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Ubiquitin-Protein Ligase Complexes, Ubiquitin-Protein Ligases, Ubiquitination
Added March 5, 2014
0 Communities
2 Members
0 Resources
16 MeSH Terms
SCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiae.
Pal B, Chan NC, Helfenbaum L, Tan K, Tansey WP, Gething MJ
(2007) Mol Biol Cell 18: 426-40
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Anaphase-Promoting Complex-Cyclosome, Basic-Leucine Zipper Transcription Factors, Binding Sites, Cell Cycle Proteins, Cell Nucleus, Cell Survival, Cyclin-Dependent Kinase 8, Cyclin-Dependent Kinases, F-Box Proteins, Mitogen-Activated Protein Kinase Kinases, Molecular Sequence Data, Mutation, Proteasome Endopeptidase Complex, Protein Folding, Repressor Proteins, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Serine, Transcription Factors, Two-Hybrid System Techniques, Ubiquitin, Ubiquitin-Conjugating Enzymes, Ubiquitin-Protein Ligase Complexes, Ubiquitin-Protein Ligases
Added March 10, 2014
0 Communities
1 Members
0 Resources
26 MeSH Terms
Role of Hcn1 and its phosphorylation in fission yeast anaphase-promoting complex/cyclosome function.
Yoon HJ, Feoktistova A, Chen JS, Jennings JL, Link AJ, Gould KL
(2006) J Biol Chem 281: 32284-93
MeSH Terms: Alanine, Amino Acid Substitution, Anaphase-Promoting Complex-Cyclosome, Cell Cycle Proteins, Fungal Proteins, G2 Phase, Gene Deletion, Green Fluorescent Proteins, Phosphorylation, Repressor Proteins, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Ubiquitin-Protein Ligase Complexes
Added April 18, 2013
0 Communities
2 Members
0 Resources
13 MeSH Terms
Pressure-induced regulation of IL-6 in retinal glial cells: involvement of the ubiquitin/proteasome pathway and NFkappaB.
Sappington RM, Calkins DJ
(2006) Invest Ophthalmol Vis Sci 47: 3860-9
MeSH Terms: Animals, Animals, Newborn, Astrocytes, Cell Separation, Cells, Cultured, Cysteine Proteinase Inhibitors, Enzyme-Linked Immunosorbent Assay, Fluorescent Antibody Technique, Indirect, Hydrostatic Pressure, Interleukin-6, Leupeptins, Microglia, NF-kappa B, RNA, Messenger, Rats, Rats, Sprague-Dawley, Retina, Reverse Transcriptase Polymerase Chain Reaction, Tetradecanoylphorbol Acetate, Ubiquitin-Protein Ligase Complexes
Added May 27, 2014
0 Communities
2 Members
0 Resources
20 MeSH Terms
Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis.
Gama V, Yoshida T, Gomez JA, Basile DP, Mayo LD, Haas AL, Matsuyama S
(2006) Exp Cell Res 312: 488-99
MeSH Terms: Acetylcysteine, Amino Acid Chloromethyl Ketones, Antigens, Nuclear, Apoptosis, Caspase Inhibitors, Cell Line, Cysteine Proteinase Inhibitors, DNA-Binding Proteins, Doxorubicin, Gene Expression, HeLa Cells, Humans, Ku Autoantigen, Leupeptins, Proteasome Endopeptidase Complex, Proteasome Inhibitors, Signal Transduction, Staurosporine, Ubiquitin, Ubiquitin-Protein Ligase Complexes
Added October 26, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex.
Carnahan RH, Feoktistova A, Ren L, Niessen S, Yates JR, Gould KL
(2005) Eukaryot Cell 4: 577-87
MeSH Terms: Anaphase-Promoting Complex-Cyclosome, Apc4 Subunit, Anaphase-Promoting Complex-Cyclosome, Cell Cycle Proteins, Humans, Macromolecular Substances, RNA Splicing, RNA, Messenger, RNA-Binding Proteins, Recombinant Fusion Proteins, Saccharomyces cerevisiae Proteins, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Two-Hybrid System Techniques, Ubiquitin-Protein Ligase Complexes
Added December 12, 2013
0 Communities
2 Members
0 Resources
14 MeSH Terms