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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 16

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Activation of the epidermal growth factor receptor in macrophages regulates cytokine production and experimental colitis.
Lu N, Wang L, Cao H, Liu L, Van Kaer L, Washington MK, Rosen MJ, Dubé PE, Wilson KT, Ren X, Hao X, Polk DB, Yan F
(2014) J Immunol 192: 1013-23
MeSH Terms: Adolescent, Adult, Aged, Animals, Cell Line, Colitis, Colitis, Ulcerative, Colon, Cyclooxygenase 2, Cytokines, Dextran Sulfate, ErbB Receptors, Female, Gene Expression Regulation, Humans, Immunity, Innate, Inflammation, Interferon-gamma, Interleukin-10, Lipopolysaccharides, Macrophage Activation, Macrophages, Male, Mice, Mice, Inbred C57BL, Middle Aged, Myeloid Cells, NF-kappa B, Neutrophils, Quinazolines, Regeneration, Signal Transduction, Spleen, Tumor Necrosis Factor-alpha, Tyrphostins, Young Adult
Added March 20, 2014
0 Communities
4 Members
0 Resources
36 MeSH Terms
Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species.
Samarakoon R, Dobberfuhl AD, Cooley C, Overstreet JM, Patel S, Goldschmeding R, Meldrum KK, Higgins PJ
(2013) Cell Signal 25: 2198-209
MeSH Terms: Animals, Benzothiazoles, Connective Tissue Growth Factor, Endothelium, Vascular, ErbB Receptors, Fibroblasts, Fibrosis, Gene Expression Regulation, Isoquinolines, Mice, Mink, Myocytes, Smooth Muscle, Pyridines, Pyrroles, Quinazolines, Rats, Reactive Oxygen Species, Renal Insufficiency, Chronic, Serpin E2, Signal Transduction, Smad2 Protein, Smad3 Protein, Toluene, Transforming Growth Factor beta1, Tumor Suppressor Protein p53, Tyrphostins
Added April 19, 2016
0 Communities
1 Members
0 Resources
26 MeSH Terms
Regulated intramembrane cleavage of the EGF receptor.
Liao HJ, Carpenter G
(2012) Traffic 13: 1106-12
MeSH Terms: Amyloid Precursor Protein Secretases, Calpain, Cell Line, Tumor, Cell Membrane, Cell Nucleus, Epidermal Growth Factor, ErbB Receptors, Gene Expression, Glycoproteins, HEK293 Cells, Humans, Ionomycin, Proteolysis, Quinazolines, Serine Endopeptidases, Serine Proteinase Inhibitors, Tyrphostins
Added August 23, 2013
0 Communities
2 Members
0 Resources
17 MeSH Terms
ErbB4 localization to cardiac myocyte nuclei, and its role in myocyte DNA damage response.
Icli B, Bharti A, Pentassuglia L, Peng X, Sawyer DB
(2012) Biochem Biophys Res Commun 418: 116-21
MeSH Terms: Animals, Cell Nucleus, Cyclin-Dependent Kinase Inhibitor p21, DNA Damage, Doxorubicin, ErbB Receptors, Heart Ventricles, Mice, Myocytes, Cardiac, Protein Kinase Inhibitors, Quinazolines, Rats, Receptor, ErbB-4, Tumor Suppressor Protein p53, Tyrphostins
Added May 28, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism.
Yan F, Cao H, Cover TL, Washington MK, Shi Y, Liu L, Chaturvedi R, Peek RM, Wilson KT, Polk DB
(2011) J Clin Invest 121: 2242-53
MeSH Terms: Administration, Rectal, Animals, Apoptosis, Bacterial Proteins, Colitis, Dextran Sulfate, Drug Evaluation, Preclinical, Enzyme Activation, Epithelial Cells, ErbB Receptors, Hydrogels, Intestinal Mucosa, Lactobacillus rhamnosus, Mice, Mice, Inbred C57BL, Microspheres, Oxazolone, Permeability, Probiotics, Proto-Oncogene Proteins c-akt, Quinazolines, Recombinant Proteins, Signal Transduction, Tyrphostins
Added March 5, 2014
0 Communities
6 Members
0 Resources
24 MeSH Terms
Maximal beta3-adrenergic regulation of lipolysis involves Src and epidermal growth factor receptor-dependent ERK1/2 activation.
Robidoux J, Kumar N, Daniel KW, Moukdar F, Cyr M, Medvedev AV, Collins S
(2006) J Biol Chem 281: 37794-802
MeSH Terms: 3T3-L1 Cells, Adipocytes, Adrenergic beta-3 Receptor Agonists, Animals, Cyclic AMP-Dependent Protein Kinases, Dioxoles, Enzyme Activation, ErbB Receptors, Estradiol, Extracellular Signal-Regulated MAP Kinases, Flavonoids, Isoquinolines, Lipolysis, Mice, Quinazolines, RNA, Small Interfering, Receptors, Adrenergic, beta-3, Sulfonamides, Tyrphostins, src-Family Kinases
Added July 22, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers.
Haruki N, Kawaguchi KS, Eichenberger S, Massion PP, Olson S, Gonzalez A, Carbone DP, Dang TP
(2005) Cancer Res 65: 3555-61
MeSH Terms: Apoptosis, Cell Cycle Proteins, Cell Growth Processes, Cell Line, Tumor, Down-Regulation, Dual Specificity Phosphatase 1, Enzyme Inhibitors, ErbB Receptors, Humans, Immediate-Early Proteins, Lung Neoplasms, MAP Kinase Signaling System, Mitogen-Activated Protein Kinases, Phosphoprotein Phosphatases, Phosphorylation, Protein Phosphatase 1, Protein Tyrosine Phosphatases, Proto-Oncogene Proteins, Quinazolines, Receptor, Notch3, Receptors, Cell Surface, Receptors, Notch, Transfection, Tyrphostins
Added March 5, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
Role for extracellular signal-responsive kinase-1 and -2 in retinal angiogenesis.
Bullard LE, Qi X, Penn JS
(2003) Invest Ophthalmol Vis Sci 44: 1722-31
MeSH Terms: Animals, Cell Division, Disease Models, Animal, Dose-Response Relationship, Drug, Endothelial Growth Factors, Endothelium, Vascular, Enzyme Inhibitors, Flavonoids, Humans, Infant, Newborn, Intercellular Signaling Peptides and Proteins, Lymphokines, MAP Kinase Signaling System, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Mitogen-Activated Protein Kinases, Phosphorylation, Rats, Rats, Sprague-Dawley, Retinal Neovascularization, Retinal Vessels, Retinopathy of Prematurity, Tyrphostins, Vascular Endothelial Growth Factor A, Vascular Endothelial Growth Factors
Added October 9, 2013
1 Communities
1 Members
0 Resources
25 MeSH Terms
Regulation of c-myc stability by selective stress conditions and by MEKK1 requires aa 127-189 of c-myc.
Alarcon-Vargas D, Tansey WP, Ronai Z
(2002) Oncogene 21: 4384-91
MeSH Terms: Antineoplastic Agents, Apoptosis, Calcium-Calmodulin-Dependent Protein Kinases, Cells, Cultured, Cycloheximide, Dactinomycin, Dose-Response Relationship, Drug, Electrophoresis, Polyacrylamide Gel, Enzyme Inhibitors, Fibroblasts, Flavonoids, Humans, Imidazoles, MAP Kinase Kinase Kinase 1, Oligopeptides, Peptide Fragments, Protein Synthesis Inhibitors, Protein-Serine-Threonine Kinases, Protein-Tyrosine Kinases, Proto-Oncogene Proteins c-myc, Pyridines, Stress, Physiological, Tumor Necrosis Factor-alpha, Tyrphostins, Ultraviolet Rays
Added March 10, 2014
0 Communities
1 Members
0 Resources
25 MeSH Terms
Metabotropic glutamate receptor 5-induced phosphorylation of extracellular signal-regulated kinase in astrocytes depends on transactivation of the epidermal growth factor receptor.
Peavy RD, Chang MS, Sanders-Bush E, Conn PJ
(2001) J Neurosci 21: 9619-28
MeSH Terms: Animals, Astrocytes, Cells, Cultured, Enzyme Inhibitors, ErbB Receptors, Excitatory Amino Acid Agonists, Excitatory Amino Acid Antagonists, GTP-Binding Protein alpha Subunits, Gq-G11, GTP-Binding Proteins, Heterotrimeric GTP-Binding Proteins, Isoenzymes, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Mitogen-Activated Protein Kinases, Peptides, Phosphatidylinositols, Phospholipase C beta, Phosphorylation, Protein Binding, Protein Subunits, Protein Tyrosine Phosphatases, Quinazolines, Rats, Rats, Sprague-Dawley, Receptor, Metabotropic Glutamate 5, Receptors, Metabotropic Glutamate, Signal Transduction, Transcriptional Activation, Type C Phospholipases, Tyrphostins, src-Family Kinases
Added February 19, 2015
0 Communities
1 Members
0 Resources
31 MeSH Terms