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Results: 1 to 10 of 10

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Bacterial Energetic Requirements for Helicobacter pylori Cag Type IV Secretion System-Dependent Alterations in Gastric Epithelial Cells.
Lin AS, Dooyema SDR, Frick-Cheng AE, Harvey ML, Suarez G, Loh JT, McDonald WH, McClain MS, Peek RM, Cover TL
(2020) Infect Immun 88:
MeSH Terms: Antigens, Bacterial, Bacterial Proteins, Biological Transport, DNA, Bacterial, Epithelial Cells, Helicobacter pylori, Humans, Interleukin-8, Lipopolysaccharides, NF-kappa B, Peptidoglycan, Toll-Like Receptor 9, Type IV Secretion Systems, Virulence Factors
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Targeted mobilization of Lrig1 gastric epithelial stem cell populations by a carcinogenic type IV secretion system.
Wroblewski LE, Choi E, Petersen C, Delgado AG, Piazuelo MB, Romero-Gallo J, Lantz TL, Zavros Y, Coffey RJ, Goldenring JR, Zemper AE, Peek RM
(2019) Proc Natl Acad Sci U S A 116: 19652-19658
MeSH Terms: Adenocarcinoma, Animals, Carcinogenesis, Disease Models, Animal, Epithelial Cells, Female, Gastric Mucosa, Gastritis, Helicobacter Infections, Helicobacter pylori, Humans, Male, Membrane Glycoproteins, Mice, Mice, Knockout, Nerve Tissue Proteins, Precancerous Conditions, Primary Cell Culture, Risk Factors, Stem Cells, Stomach, Stomach Neoplasms, Type IV Secretion Systems
Added September 27, 2019
1 Communities
1 Members
0 Resources
23 MeSH Terms
Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP.
Byndloss MX, Tsai AY, Walker GT, Miller CN, Young BM, English BC, Seyffert N, Kerrinnes T, de Jong MF, Atluri VL, Winter MG, Celli J, Tsolis RM
(2019) mBio 10:
MeSH Terms: Animals, Brucella abortus, Cell Death, Endoplasmic Reticulum Stress, Female, Mice, Mice, Inbred C57BL, Nod1 Signaling Adaptor Protein, Nod2 Signaling Adaptor Protein, Placenta, Pregnancy, Transcription Factor CHOP, Trophoblasts, Type IV Secretion Systems, Unfolded Protein Response
Added March 30, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Structure of the Cag type IV secretion system.
Chung JM, Sheedlo MJ, Campbell AM, Sawhney N, Frick-Cheng AE, Lacy DB, Cover TL, Ohi MD
(2019) Elife 8:
MeSH Terms: Bacterial Outer Membrane Proteins, Helicobacter pylori, Models, Molecular, Type IV Secretion Systems
Added July 14, 2019
0 Communities
3 Members
0 Resources
4 MeSH Terms
Molecular Architecture of the Helicobacter pylori Cag Type IV Secretion System.
Hu B, Khara P, Song L, Lin AS, Frick-Cheng AE, Harvey ML, Cover TL, Christie PJ
(2019) mBio 10:
MeSH Terms: Antigens, Bacterial, Bacterial Proteins, Cryoelectron Microscopy, Genomic Islands, Helicobacter pylori, Humans, Type IV Secretion Systems
Added July 14, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
How bacterial pathogens use type III and type IV secretion systems to facilitate their transmission.
Byndloss MX, Rivera-Chávez F, Tsolis RM, Bäumler AJ
(2017) Curr Opin Microbiol 35: 1-7
MeSH Terms: Animals, Brucella, Brucellosis, Gram-Negative Bacteria, Gram-Negative Bacterial Infections, Host-Pathogen Interactions, Humans, Protein Transport, Salmonella, Salmonella Infections, Type III Secretion Systems, Type IV Secretion Systems, Virulence Factors
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Pathogenic Helicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system.
Varga MG, Shaffer CL, Sierra JC, Suarez G, Piazuelo MB, Whitaker ME, Romero-Gallo J, Krishna US, Delgado A, Gomez MA, Good JA, Almqvist F, Skaar EP, Correa P, Wilson KT, Hadjifrangiskou M, Peek RM
(2016) Oncogene 35: 6262-6269
MeSH Terms: Bacterial Proteins, Biological Transport, Carcinogenesis, DNA, Bacterial, Helicobacter Infections, Helicobacter pylori, Humans, Mutation, Stomach Neoplasms, Toll-Like Receptor 9, Type IV Secretion Systems
Added May 15, 2016
0 Communities
2 Members
0 Resources
11 MeSH Terms
Peptidomimetic Small Molecules Disrupt Type IV Secretion System Activity in Diverse Bacterial Pathogens.
Shaffer CL, Good JA, Kumar S, Krishnan KS, Gaddy JA, Loh JT, Chappell J, Almqvist F, Cover TL, Hadjifrangiskou M
(2016) mBio 7: e00221-16
MeSH Terms: Agrobacterium tumefaciens, Bacterial Proteins, Escherichia coli, Helicobacter Infections, Helicobacter pylori, Humans, Peptidomimetics, Plant Diseases, Protein Transport, Small Molecule Libraries, Type IV Secretion Systems
Added May 5, 2016
0 Communities
2 Members
0 Resources
11 MeSH Terms
Molecular and Structural Analysis of the Helicobacter pylori cag Type IV Secretion System Core Complex.
Frick-Cheng AE, Pyburn TM, Voss BJ, McDonald WH, Ohi MD, Cover TL
(2016) mBio 7: e02001-15
MeSH Terms: Helicobacter pylori, Humans, Immunohistochemistry, Macromolecular Substances, Microscopy, Electron, Type IV Secretion Systems
Added January 26, 2016
0 Communities
4 Members
0 Resources
6 MeSH Terms
High resolution electron microscopy of the Helicobacter pylori Cag type IV secretion system pili produced in varying conditions of iron availability.
Haley KP, Blanz EJ, Gaddy JA
(2014) J Vis Exp : e52122
MeSH Terms: Epithelial Cells, Fimbriae, Bacterial, Gastric Mucosa, Genomic Islands, Helicobacter Infections, Helicobacter pylori, Humans, Iron, Microscopy, Electron, Signal Transduction, Type IV Secretion Systems, Virulence Factors
Added January 20, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms