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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 47

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Biased M receptor-positive allosteric modulators reveal role of phospholipase D in M-dependent rodent cortical plasticity.
Moran SP, Xiang Z, Doyle CA, Maksymetz J, Lv X, Faltin S, Fisher NM, Niswender CM, Rook JM, Lindsley CW, Conn PJ
(2019) Sci Signal 12:
MeSH Terms: Allosteric Site, Animals, CHO Cells, Calcium, Cerebral Cortex, Cognition, Cricetinae, Cricetulus, Electrophysiology, Female, Humans, Long-Term Synaptic Depression, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Neuronal Plasticity, Phospholipase D, Prefrontal Cortex, Receptor, Muscarinic M1, Signal Transduction, Type C Phospholipases
Added March 3, 2020
0 Communities
2 Members
0 Resources
22 MeSH Terms
Suboptimal activation of protease-activated receptors enhances alpha2beta1 integrin-mediated platelet adhesion to collagen.
Marjoram RJ, Voss B, Pan Y, Dickeson SK, Zutter MM, Hamm HE, Santoro SA
(2009) J Biol Chem 284: 34640-7
MeSH Terms: Amino Acid Motifs, Animals, Blood Platelets, Carrier Proteins, Collagen, GTP-Binding Protein alpha Subunits, Gi-Go, Humans, Integrin alpha2beta1, Mice, Mice, Inbred C57BL, Peptides, Platelet Adhesiveness, Platelet Aggregation, Platelet Membrane Glycoproteins, Rats, Receptor, PAR-1, Receptors, Collagen, Receptors, G-Protein-Coupled, Receptors, IgG, Receptors, Thrombin, Signal Transduction, Thrombin, Type C Phospholipases
Added December 10, 2013
1 Communities
2 Members
0 Resources
23 MeSH Terms
Multiple pathways involved in the biosynthesis of anandamide.
Liu J, Wang L, Harvey-White J, Huang BX, Kim HY, Luquet S, Palmiter RD, Krystal G, Rai R, Mahadevan A, Razdan RK, Kunos G
(2008) Neuropharmacology 54: 1-7
MeSH Terms: Animals, Arachidonic Acids, Cell Line, Transformed, Chromatography, High Pressure Liquid, Chromatography, Thin Layer, Drug Interactions, Endocannabinoids, Glycerophosphates, Hydrolases, Hydrolysis, Inositol Polyphosphate 5-Phosphatases, Lipopolysaccharides, Macrophages, Metabolic Networks and Pathways, Mice, Mice, Knockout, Neomycin, Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases, Phospholipase D, Phosphoric Monoester Hydrolases, Polyunsaturated Alkamides, Protein Synthesis Inhibitors, Protein Tyrosine Phosphatase, Non-Receptor Type 22, RNA, Small Interfering, Transfection, Type C Phospholipases
Added April 10, 2014
0 Communities
0 Members
1 Resources
26 MeSH Terms
Cytoplasmic remodeling of erythrocyte raft lipids during infection by the human malaria parasite Plasmodium falciparum.
Murphy SC, Fernandez-Pol S, Chung PH, Prasanna Murthy SN, Milne SB, Salomao M, Brown HA, Lomasney JW, Mohandas N, Haldar K
(2007) Blood 110: 2132-9
MeSH Terms: Animals, Annexin A5, Blotting, Western, Cell Membrane, Cytoplasm, Endocytosis, Erythrocyte Membrane, Erythrocytes, Flow Cytometry, Green Fluorescent Proteins, Humans, Isoenzymes, Liposomes, Malaria, Mass Spectrometry, Membrane Microdomains, Parasitemia, Phosphatidylethanolamines, Phosphatidylglycerols, Phosphatidylinositol 4,5-Diphosphate, Phosphatidylinositols, Phospholipase C delta, Plasmodium falciparum, Primaquine, Type C Phospholipases, Vacuoles
Added March 21, 2013
0 Communities
1 Members
0 Resources
26 MeSH Terms
Acute tissue-type plasminogen activator release in human microvascular endothelial cells: the roles of Galphaq, PLC-beta, IP3 and 5,6-epoxyeicosatrienoic acid.
Muldowney JA, Painter CA, Sanders-Bush E, Brown NJ, Vaughan DE
(2007) Thromb Haemost 97: 263-71
MeSH Terms: 8,11,14-Eicosatrienoic Acid, Aorta, Biological Factors, Cell Proliferation, Cells, Cultured, Dose-Response Relationship, Drug, Endothelial Cells, Epoprostenol, GTP-Binding Protein alpha Subunits, Gq-G11, Humans, Inositol 1,4,5-Trisphosphate, Isoenzymes, Microcirculation, Nitric Oxide, Phospholipase C beta, Potassium, Signal Transduction, Thrombin, Time Factors, Tissue Plasminogen Activator, Type C Phospholipases, Umbilical Veins
Added December 10, 2013
0 Communities
1 Members
0 Resources
22 MeSH Terms
Mitochondrial calcium transport is regulated by P2Y1- and P2Y2-like mitochondrial receptors.
Belous AE, Jones CM, Wakata A, Knox CD, Nicoud IB, Pierce J, Chari RS
(2006) J Cell Biochem 99: 1165-74
MeSH Terms: Adenosine Diphosphate, Adenylyl Imidodiphosphate, Animals, Calcium, Calcium Signaling, Ion Transport, Ligands, Male, Mitochondria, Mitochondrial Proteins, Models, Biological, Purinergic P2 Receptor Agonists, Rats, Rats, Sprague-Dawley, Receptors, Purinergic P2, Receptors, Purinergic P2Y1, Receptors, Purinergic P2Y2, Type C Phospholipases
Added January 10, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Inhibition of phospholipase C attenuates liver mitochondrial calcium overload following cold ischemia.
Knox CD, Pierce JM, Nicoud IB, Belous AE, Jones CM, Anderson CD, Chari RS
(2006) Transplantation 81: 567-72
MeSH Terms: Adenosine Triphosphate, Animals, Biological Transport, Calcium, Ischemia, Liver, Male, Mitochondria, Liver, Rats, Rats, Sprague-Dawley, Type C Phospholipases
Added January 10, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
RACK1 binds to a signal transfer region of G betagamma and inhibits phospholipase C beta2 activation.
Chen S, Lin F, Hamm HE
(2005) J Biol Chem 280: 33445-52
MeSH Terms: Amino Acid Sequence, Animals, Binding Sites, Binding, Competitive, Carrier Proteins, Conserved Sequence, Enzyme Activation, Escherichia coli, GTP-Binding Protein beta Subunits, GTP-Binding Protein gamma Subunits, Glutathione Transferase, Isoenzymes, Maltose-Binding Proteins, Mice, Models, Molecular, Molecular Sequence Data, Mutagenesis, Site-Directed, Mutation, Neuropeptides, Phospholipase C beta, Protein Binding, Protein Isoforms, Receptors for Activated C Kinase, Recombinant Fusion Proteins, Sequence Homology, Amino Acid, Spectrometry, Fluorescence, Spodoptera, Type C Phospholipases
Added January 20, 2015
0 Communities
1 Members
0 Resources
28 MeSH Terms
Regulation of xanthine oxidoreductase protein expression by hydrogen peroxide and calcium.
McNally JS, Saxena A, Cai H, Dikalov S, Harrison DG
(2005) Arterioscler Thromb Vasc Biol 25: 1623-8
MeSH Terms: Animals, Calcimycin, Calcium, Cattle, Cells, Cultured, Endothelial Cells, Hydrogen Peroxide, Ionophores, Nitric Oxide, Oxidants, Superoxides, Type C Phospholipases, Xanthine Dehydrogenase, Xanthine Oxidase
Added February 17, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
Integrin-dependent PLC-gamma1 phosphorylation mediates fibronectin-dependent adhesion.
Tvorogov D, Wang XJ, Zent R, Carpenter G
(2005) J Cell Sci 118: 601-10
MeSH Terms: Animals, Cell Adhesion, Cell Line, Cell Movement, Fibroblasts, Fibronectins, Focal Adhesion Kinase 1, Focal Adhesion Protein-Tyrosine Kinases, Integrin beta1, Integrins, Mice, Mice, Knockout, Phospholipase C gamma, Phosphorylation, Protein Binding, Protein-Tyrosine Kinases, Type C Phospholipases, Tyrosine, src-Family Kinases
Added December 10, 2013
1 Communities
1 Members
0 Resources
19 MeSH Terms