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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 31

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Substrate stiffness heterogeneities disrupt endothelial barrier integrity in a micropillar model of heterogeneous vascular stiffening.
VanderBurgh JA, Hotchkiss H, Potharazu A, Taufalele PV, Reinhart-King CA
(2018) Integr Biol (Camb) 10: 734-746
MeSH Terms: Adherens Junctions, Animals, Aorta, Atherosclerosis, Cattle, Cell Adhesion, Cell Communication, Cell Movement, Dimethylpolysiloxanes, Endothelial Cells, Endothelium, Vascular, Focal Adhesions, Human Umbilical Vein Endothelial Cells, Humans, Leukocytes, Materials Testing, Neutrophils, Phenotype, Tunica Intima, Vascular Stiffness, Vinculin
Added April 10, 2019
0 Communities
1 Members
0 Resources
21 MeSH Terms
The Role of Age-Related Intimal Remodeling and Stiffening in Atherosclerosis.
VanderBurgh JA, Reinhart-King CA
(2018) Adv Pharmacol 81: 365-391
MeSH Terms: Aging, Animals, Atherosclerosis, Extracellular Matrix, Humans, Tunica Intima, Vascular Remodeling, Vascular Stiffness
Added April 10, 2019
0 Communities
1 Members
0 Resources
8 MeSH Terms
MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia.
Evans BC, Hocking KM, Osgood MJ, Voskresensky I, Dmowska J, Kilchrist KV, Brophy CM, Duvall CL
(2015) Sci Transl Med 7: 291ra95
MeSH Terms: Animals, Endocytosis, Endosomes, Humans, Hyperplasia, Intracellular Signaling Peptides and Proteins, Lysosomes, Male, Myocytes, Smooth Muscle, Nanoparticles, Peptides, Phenotype, Phosphorylation, Protein Kinase Inhibitors, Protein Serine-Threonine Kinases, Rabbits, Saphenous Vein, Treatment Outcome, Tunica Intima, Vascular Grafting
Added March 14, 2018
0 Communities
1 Members
0 Resources
20 MeSH Terms
Differential role of an NF-κB transcriptional response element in endothelial versus intimal cell VCAM-1 expression.
Milstone DS, Ilyama M, Chen M, O'Donnell P, Davis VM, Plutzky J, Brown JD, Haldar SM, Siu A, Lau AC, Zhu SN, Basheer MF, Collins T, Jongstra-Bilen J, Cybulsky MI
(2015) Circ Res 117: 166-77
MeSH Terms: 5' Untranslated Regions, Animals, Atherosclerosis, Carotid Artery Injuries, Cells, Cultured, Chemotaxis, Leukocyte, Cholesterol, Dietary, E-Selectin, Endothelial Cells, Endothelium, Vascular, Humans, Mice, Mice, Inbred C57BL, Mice, Knockout, Promoter Regions, Genetic, Protein Interaction Mapping, RNA Polymerase II, Receptors, LDL, Response Elements, Transcription Factor RelA, Transcription, Genetic, Tunica Intima, Vascular Cell Adhesion Molecule-1
Added September 6, 2016
0 Communities
1 Members
0 Resources
23 MeSH Terms
Systemic delivery of microRNA-181b inhibits nuclear factor-κB activation, vascular inflammation, and atherosclerosis in apolipoprotein E-deficient mice.
Sun X, He S, Wara AKM, Icli B, Shvartz E, Tesmenitsky Y, Belkin N, Li D, Blackwell TS, Sukhova GK, Croce K, Feinberg MW
(2014) Circ Res 114: 32-40
MeSH Terms: Animals, Aorta, Apolipoproteins E, Atherosclerosis, CD4-Positive T-Lymphocytes, Diet, High-Fat, Human Umbilical Vein Endothelial Cells, Humans, Inflammation, Karyopherins, Macrophages, Mice, Mice, Inbred C57BL, MicroRNAs, NF-kappa B, Tunica Intima
Added March 7, 2014
1 Communities
1 Members
0 Resources
16 MeSH Terms
Surgical vein graft preparation promotes cellular dysfunction, oxidative stress, and intimal hyperplasia in human saphenous vein.
Osgood MJ, Hocking KM, Voskresensky IV, Li FD, Komalavilas P, Cheung-Flynn J, Brophy CM
(2014) J Vasc Surg 60: 202-11
MeSH Terms: Aged, Endothelium, Vascular, Female, Humans, Hydrogen Peroxide, Hyperplasia, Male, Middle Aged, Muscle, Smooth, Vascular, Nitric Oxide Synthase, Organ Culture Techniques, Oxidative Stress, Platelet Endothelial Cell Adhesion Molecule-1, Reactive Oxygen Species, Saphenous Vein, Time Factors, Tunica Intima, Vascular Surgical Procedures, Warm Ischemia
Added March 9, 2015
0 Communities
2 Members
0 Resources
19 MeSH Terms
Variants in adiponectin signaling pathway genes show little association with subclinical CVD in the diabetes heart study.
Cox AJ, Lambird JE, An SS, Register TC, Langefeld CD, Carr JJ, Freedman BI, Bowden DW
(2013) Obesity (Silver Spring) 21: E456-62
MeSH Terms: Adaptor Proteins, Signal Transducing, Adiponectin, Aged, Cardiovascular Diseases, Diabetes Complications, Diabetes Mellitus, Type 2, Female, Genotype, Humans, Inflammation, Lipids, Male, Middle Aged, Muramidase, Obesity, Phenotype, Plaque, Atherosclerotic, Polymorphism, Single Nucleotide, Receptors, Adiponectin, Signal Transduction, Tunica Intima, Tunica Media, Vascular Calcification, Whites
Added February 15, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
Intimal thickness associated with endothelial dysfunction in human vein grafts.
Li FD, Sexton KW, Hocking KM, Osgood MJ, Eagle S, Cheung-Flynn J, Brophy CM, Komalavilas P
(2013) J Surg Res 180: e55-62
MeSH Terms: Endothelium, Vascular, Humans, Hyperplasia, Organ Culture Techniques, Saphenous Vein, Tunica Intima, Vasodilation
Added March 9, 2015
0 Communities
2 Members
0 Resources
7 MeSH Terms
Inhibition of Mitogen Activated Protein Kinase Activated Protein Kinase II with MMI-0100 reduces intimal hyperplasia ex vivo and in vivo.
Muto A, Panitch A, Kim N, Park K, Komalavilas P, Brophy CM, Dardik A
(2012) Vascul Pharmacol 56: 47-55
MeSH Terms: Amino Acid Sequence, Animals, Anti-Inflammatory Agents, Cell Proliferation, Cells, Cultured, Endothelial Cells, Fibrosis, Graft Occlusion, Vascular, Humans, Hyperplasia, Interleukin-6, Interleukin-8, Intracellular Signaling Peptides and Proteins, Mice, Molecular Sequence Data, Myocytes, Smooth Muscle, Nitroprusside, Peptides, Protein Kinase Inhibitors, Protein Serine-Threonine Kinases, Saphenous Vein, Tunica Intima, Vasodilation
Added March 9, 2015
0 Communities
1 Members
0 Resources
23 MeSH Terms
A novel cell permeant peptide inhibitor of MAPKAP kinase II inhibits intimal hyperplasia in a human saphenous vein organ culture model.
Lopes LB, Brophy CM, Flynn CR, Yi Z, Bowen BP, Smoke C, Seal B, Panitch A, Komalavilas P
(2010) J Vasc Surg 52: 1596-607
MeSH Terms: Animals, Aorta, Arsenites, Cell Movement, Cells, Cultured, Collagen, Connective Tissue Growth Factor, Enzyme Inhibitors, Fibronectins, HSP27 Heat-Shock Proteins, Heat-Shock Proteins, Humans, Hyperplasia, Intracellular Signaling Peptides and Proteins, Lysophospholipids, Microscopy, Confocal, Molecular Chaperones, Muscle, Smooth, Vascular, Peptides, Phosphorylation, Protein Array Analysis, Protein Serine-Threonine Kinases, Rats, Saphenous Vein, Sodium Compounds, Tissue Culture Techniques, Tunica Intima, p38 Mitogen-Activated Protein Kinases
Added March 9, 2015
0 Communities
2 Members
0 Resources
28 MeSH Terms