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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 13

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miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway.
Riquelme I, Tapia O, Leal P, Sandoval A, Varga MG, Letelier P, Buchegger K, Bizama C, Espinoza JA, Peek RM, Araya JC, Roa JC
(2016) Cell Oncol (Dordr) 39: 23-33
MeSH Terms: Base Sequence, Cell Death, Cell Line, Tumor, Cell Movement, Cell Proliferation, Cell Survival, Class I Phosphatidylinositol 3-Kinases, Down-Regulation, Gene Expression Regulation, Neoplastic, Genes, Tumor Suppressor, Humans, MicroRNAs, Models, Biological, Molecular Sequence Data, Neoplasm Invasiveness, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Signal Transduction, Stomach Neoplasms, TOR Serine-Threonine Kinases, Transfection, Tuberous Sclerosis Complex 1 Protein, Tumor Stem Cell Assay, Tumor Suppressor Proteins
Added February 5, 2016
0 Communities
1 Members
0 Resources
24 MeSH Terms
The α₂β₁ integrin is a metastasis suppressor in mouse models and human cancer.
Ramirez NE, Zhang Z, Madamanchi A, Boyd KL, O'Rear LD, Nashabi A, Li Z, Dupont WD, Zijlstra A, Zutter MM
(2011) J Clin Invest 121: 226-37
MeSH Terms: Animals, Base Sequence, Biomarkers, Tumor, Breast Neoplasms, DNA Primers, Female, Genes, erbB-2, Humans, In Vitro Techniques, Integrin alpha2beta1, Kaplan-Meier Estimate, Male, Mammary Neoplasms, Experimental, Mice, Mice, Knockout, Mice, Transgenic, Neoplasm Invasiveness, Neoplasm Metastasis, Prognosis, Prostatic Neoplasms, Tumor Stem Cell Assay, Tumor Suppressor Proteins
Added February 16, 2014
2 Communities
4 Members
0 Resources
22 MeSH Terms
Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis.
Nagaraj NS, Smith JJ, Revetta F, Washington MK, Merchant NB
(2010) Mol Cancer Ther 9: 2322-32
MeSH Terms: Apoptosis, Cell Cycle, Cell Line, Tumor, Cell Proliferation, Dasatinib, Disease Progression, Humans, Neoplasm Metastasis, Pancreas, Pancreatic Neoplasms, Protein Kinase Inhibitors, Pyrimidines, Signal Transduction, Thiazoles, Tumor Stem Cell Assay, src-Family Kinases
Added June 14, 2013
0 Communities
3 Members
0 Resources
16 MeSH Terms
Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair.
Wiltshire TD, Lovejoy CA, Wang T, Xia F, O'Connor MJ, Cortez D
(2010) J Biol Chem 285: 14565-71
MeSH Terms: Blotting, Western, Bone Neoplasms, Cell Survival, DNA Breaks, Double-Stranded, DNA Repair, Fluorescent Antibody Technique, Humans, Intracellular Signaling Peptides and Proteins, Osteosarcoma, Phthalazines, Piperazines, Poly(ADP-ribose) Polymerase Inhibitors, Poly(ADP-ribose) Polymerases, RNA, Messenger, RNA, Small Interfering, Rad51 Recombinase, Radiation, Ionizing, Recombination, Genetic, Reverse Transcriptase Polymerase Chain Reaction, Thiolester Hydrolases, Tumor Cells, Cultured, Tumor Stem Cell Assay, Tumor Suppressor p53-Binding Protein 1
Added March 5, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Cytosolic phospholipase A2: targeting cancer through the tumor vasculature.
Linkous A, Geng L, Lyshchik A, Hallahan DE, Yazlovitskaya EM
(2009) Clin Cancer Res 15: 1635-44
MeSH Terms: Animals, Apoptosis, Arachidonic Acids, Blood Flow Velocity, Blotting, Western, Carcinoma, Large Cell, Carcinoma, Lewis Lung, Cell Movement, Collagen, Disease Models, Animal, Drug Combinations, Endothelium, Vascular, Enzyme Inhibitors, Laminin, Lung Neoplasms, Mice, Mice, Inbred C57BL, Mice, Nude, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Neovascularization, Pathologic, Phospholipases A2, Cytosolic, Phosphorylation, Proteoglycans, Proto-Oncogene Proteins c-akt, Radiation Dosage, Tumor Stem Cell Assay
Added August 21, 2013
0 Communities
1 Members
0 Resources
27 MeSH Terms
Increased efficiency for performing colony formation assays in 96-well plates: novel applications to combination therapies and high-throughput screening.
Katz D, Ito E, Lau KS, Mocanu JD, Bastianutto C, Schimmer AD, Liu FF
(2008) Biotechniques 44: ix-xiv
MeSH Terms: Cell Line, Tumor, Cisplatin, Combined Modality Therapy, Dose-Response Relationship, Drug, Dose-Response Relationship, Radiation, Humans, Reproducibility of Results, Small Molecule Libraries, Tumor Stem Cell Assay
Added November 15, 2013
0 Communities
1 Members
0 Resources
9 MeSH Terms
Drug-induced inactivation or gene silencing of class I histone deacetylases suppresses ovarian cancer cell growth: implications for therapy.
Khabele D, Son DS, Parl AK, Goldberg GL, Augenlicht LH, Mariadason JM, Rice VM
(2007) Cancer Biol Ther 6: 795-801
MeSH Terms: Acetylation, Adult, Aged, Antibiotics, Antineoplastic, Blotting, Western, Butyrates, Carcinoma, Papillary, Cell Proliferation, Cystadenocarcinoma, Serous, Depsipeptides, Disease Progression, Enzyme Inhibitors, Female, Gene Expression Regulation, Enzymologic, Gene Silencing, Histone Deacetylase 1, Histone Deacetylases, Humans, Hydroxamic Acids, Middle Aged, Ovarian Neoplasms, RNA, Small Interfering, Transcription, Genetic, Tumor Cells, Cultured, Tumor Stem Cell Assay, Vorinostat
Added March 5, 2014
0 Communities
1 Members
0 Resources
26 MeSH Terms
Raf and RhoA cooperate to transform intestinal epithelial cells and induce growth resistance to transforming growth factor beta.
Du J, Jiang B, Coffey RJ, Barnard J
(2004) Mol Cancer Res 2: 233-41
MeSH Terms: Alkyl and Aryl Transferases, Animals, Cell Division, Cell Line, Cell Transformation, Neoplastic, Enzyme Activation, Farnesyltranstransferase, Gene Expression Regulation, Neoplastic, Genes, Dominant, Intestinal Mucosa, Methionine, Mice, Mutation, Proto-Oncogene Proteins c-raf, Proto-Oncogene Proteins p21(ras), Rats, Transfection, Transforming Growth Factor beta, Tumor Stem Cell Assay, Xenograft Model Antitumor Assays, rhoA GTP-Binding Protein
Added August 12, 2010
1 Communities
1 Members
0 Resources
21 MeSH Terms
CRBP suppresses breast cancer cell survival and anchorage-independent growth.
Kuppumbatti YS, Rexer B, Nakajo S, Nakaya K, Mira-y-Lopez R
(2001) Oncogene 20: 7413-9
MeSH Terms: Agar, Apoptosis, Breast, Breast Neoplasms, Carrier Proteins, Cell Adhesion, Cell Division, Cell Line, Transformed, Cell Transformation, Viral, Chromones, Contact Inhibition, Enzyme Activation, Enzyme Inhibitors, Fatty Acid-Binding Protein 7, Fatty Acid-Binding Proteins, Female, Humans, Morpholines, Neoplasm Proteins, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Protein Serine-Threonine Kinases, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-akt, Receptors, Retinoic Acid, Retinol-Binding Proteins, Retinol-Binding Proteins, Cellular, Signal Transduction, Simian virus 40, Tretinoin, Tumor Stem Cell Assay, Tumor Suppressor Proteins, Vitamin A
Added March 10, 2014
0 Communities
1 Members
0 Resources
33 MeSH Terms
Radiopotentiation by the oral platinum agent, JM216: role of repair inhibition.
Amorino GP, Freeman ML, Carbone DP, Lebwohl DE, Choy H
(1999) Int J Radiat Oncol Biol Phys 44: 399-405
MeSH Terms: Administration, Oral, Animals, Antineoplastic Agents, Carboplatin, Cell Survival, Cisplatin, Combined Modality Therapy, Cricetinae, Cricetulus, DNA Damage, DNA Repair, DNA, Neoplasm, Dose-Response Relationship, Drug, Humans, Organoplatinum Compounds, Radiation Tolerance, Radiobiology, Tumor Cells, Cultured, Tumor Stem Cell Assay
Added March 5, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms