Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 28

Publication Record

Connections

Inactivation of in Abcg2 lineage-derived cells drives the appearance of polycystic lesions and fibrosis in the adult kidney.
Gewin LS, Summers ME, Harral JW, Gaskill CF, Khodo SN, Neelisetty S, Sullivan TM, Hopp K, Reese JJ, Klemm DJ, Kon V, Ess KC, Shi W, Majka SM
(2019) Am J Physiol Renal Physiol 317: F1201-F1210
MeSH Terms: ATP Binding Cassette Transporter, Subfamily G, Member 2, Animals, Cell Lineage, Female, Fibrosis, Kidney Tubules, Proximal, Male, Mice, Myofibroblasts, Polycystic Kidney Diseases, Selective Estrogen Receptor Modulators, Tamoxifen, Tuberous Sclerosis Complex 2 Protein
Added March 18, 2020
0 Communities
2 Members
0 Resources
13 MeSH Terms
Location-dependent maintenance of intrinsic susceptibility to mTORC1-driven tumorigenesis.
Rushing GV, Brockman AA, Bollig MK, Leelatian N, Mobley BC, Irish JM, Ess KC, Fu C, Ihrie RA
(2019) Life Sci Alliance 2:
MeSH Terms: Adolescent, Animals, Astrocytoma, Carcinogenesis, Cells, Cultured, Child, Child, Preschool, Disease Susceptibility, Female, Humans, Lateral Ventricles, Male, Mechanistic Target of Rapamycin Complex 1, Mice, Mice, Inbred C57BL, Neural Stem Cells, Signal Transduction, Thyroid Nuclear Factor 1, Tuberous Sclerosis
Added March 27, 2019
2 Communities
2 Members
0 Resources
19 MeSH Terms
Heterozygous loss of TSC2 alters p53 signaling and human stem cell reprogramming.
Armstrong LC, Westlake G, Snow JP, Cawthon B, Armour E, Bowman AB, Ess KC
(2017) Hum Mol Genet 26: 4629-4641
MeSH Terms: Adolescent, Adult, Alleles, Cellular Reprogramming, Child, Child, Preschool, Female, Fibroblasts, Genes, p53, Heterozygote, Humans, Induced Pluripotent Stem Cells, Infant, Loss of Heterozygosity, Male, Mutation, RNA, Small Interfering, Signal Transduction, TOR Serine-Threonine Kinases, Tuberous Sclerosis, Tuberous Sclerosis Complex 1 Protein, Tuberous Sclerosis Complex 2 Protein, Tumor Suppressor Protein p53, Tumor Suppressor Proteins
Added April 11, 2018
0 Communities
1 Members
0 Resources
24 MeSH Terms
miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway.
Riquelme I, Tapia O, Leal P, Sandoval A, Varga MG, Letelier P, Buchegger K, Bizama C, Espinoza JA, Peek RM, Araya JC, Roa JC
(2016) Cell Oncol (Dordr) 39: 23-33
MeSH Terms: Base Sequence, Cell Death, Cell Line, Tumor, Cell Movement, Cell Proliferation, Cell Survival, Class I Phosphatidylinositol 3-Kinases, Down-Regulation, Gene Expression Regulation, Neoplastic, Genes, Tumor Suppressor, Humans, MicroRNAs, Models, Biological, Molecular Sequence Data, Neoplasm Invasiveness, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Signal Transduction, Stomach Neoplasms, TOR Serine-Threonine Kinases, Transfection, Tuberous Sclerosis Complex 1 Protein, Tumor Stem Cell Assay, Tumor Suppressor Proteins
Added February 5, 2016
0 Communities
1 Members
0 Resources
24 MeSH Terms
Dynamic tubers in tuberous sclerosis complex: A window for intervention?
Ess KC, Chugani HT
(2015) Neurology 85: 1530-1
MeSH Terms: Brain, Female, Humans, Male, Tuberous Sclerosis, White Matter
Added February 16, 2016
0 Communities
1 Members
0 Resources
6 MeSH Terms
Evaluation of diffusion kurtosis imaging in ex vivo hypomyelinated mouse brains.
Kelm ND, West KL, Carson RP, Gochberg DF, Ess KC, Does MD
(2016) Neuroimage 124: 612-626
MeSH Terms: Animals, Axons, Brain, Carrier Proteins, Diffusion, Diffusion Tensor Imaging, Disease Models, Animal, Magnetic Resonance Imaging, Mice, Mice, Knockout, Myelin Sheath, Rapamycin-Insensitive Companion of mTOR Protein, Tuberous Sclerosis, Tuberous Sclerosis Complex 2 Protein, Tumor Suppressor Proteins, White Matter
Added February 16, 2016
0 Communities
1 Members
0 Resources
16 MeSH Terms
Tuberous sclerosis associated neuropsychiatric disorders (TAND) and the TAND Checklist.
de Vries PJ, Whittemore VH, Leclezio L, Byars AW, Dunn D, Ess KC, Hook D, King BH, Sahin M, Jansen A
(2015) Pediatr Neurol 52: 25-35
MeSH Terms: Adolescent, Adult, Brain Diseases, Checklist, Child, Child, Preschool, Humans, Infant, Mental Disorders, Pilot Projects, Terminology as Topic, Tuberous Sclerosis
Added February 16, 2016
0 Communities
1 Members
0 Resources
12 MeSH Terms
PIP4kγ is a substrate for mTORC1 that maintains basal mTORC1 signaling during starvation.
Mackey AM, Sarkes DA, Bettencourt I, Asara JM, Rameh LE
(2014) Sci Signal 7: ra104
MeSH Terms: Animals, Cytoplasm, Fibroblasts, HEK293 Cells, HeLa Cells, Humans, Mechanistic Target of Rapamycin Complex 1, Mice, Multiprotein Complexes, Mutation, Phosphorylation, Phosphotransferases (Alcohol Group Acceptor), Signal Transduction, TOR Serine-Threonine Kinases, Tuberous Sclerosis Complex 2 Protein, Tumor Suppressor Proteins
Added November 26, 2018
0 Communities
1 Members
0 Resources
16 MeSH Terms
Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish.
Kim SH, Kowalski ML, Carson RP, Bridges LR, Ess KC
(2013) Dis Model Mech 6: 925-33
MeSH Terms: Abdominal Neoplasms, Alleles, Animals, Blood Vessels, Cell Transformation, Neoplastic, Gene Silencing, Heterozygote, Intracellular Signaling Peptides and Proteins, Mechanistic Target of Rapamycin Complex 1, Mechanistic Target of Rapamycin Complex 2, Multiprotein Complexes, Mutation, Neovascularization, Pathologic, Proto-Oncogene Proteins c-akt, Signal Transduction, Sirolimus, TOR Serine-Threonine Kinases, Tuberous Sclerosis Complex 2 Protein, Tumor Suppressor Protein p53, Tumor Suppressor Proteins, Up-Regulation, Vascular Endothelial Growth Factor A, Zebrafish, Zebrafish Proteins
Added September 24, 2013
1 Communities
2 Members
0 Resources
24 MeSH Terms
Conditional and domain-specific inactivation of the Tsc2 gene in neural progenitor cells.
Fu C, Ess KC
(2013) Genesis 51: 284-92
MeSH Terms: Alleles, Animals, Brain, Exons, Founder Effect, Gene Deletion, Gene Knock-In Techniques, Homozygote, Mice, Mice, Transgenic, Neural Stem Cells, Protein Structure, Tertiary, TOR Serine-Threonine Kinases, Tuberous Sclerosis Complex 1 Protein, Tumor Suppressor Proteins
Added December 2, 2013
2 Communities
1 Members
0 Resources
15 MeSH Terms