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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 50

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Targeting MYCN-expressing triple-negative breast cancer with BET and MEK inhibitors.
Schafer JM, Lehmann BD, Gonzalez-Ericsson PI, Marshall CB, Beeler JS, Redman LN, Jin H, Sanchez V, Stubbs MC, Scherle P, Johnson KN, Sheng Q, Roland JT, Bauer JA, Shyr Y, Chakravarthy B, Mobley BC, Hiebert SW, Balko JM, Sanders ME, Liu PCC, Pietenpol JA
(2020) Sci Transl Med 12:
MeSH Terms: Animals, Cell Line, Tumor, Humans, Mitogen-Activated Protein Kinase Kinases, N-Myc Proto-Oncogene Protein, Neoplasm Recurrence, Local, Proteins, Triple Negative Breast Neoplasms, Xenograft Model Antitumor Assays
Added March 30, 2020
0 Communities
1 Members
0 Resources
9 MeSH Terms
TBCRC 032 IB/II Multicenter Study: Molecular Insights to AR Antagonist and PI3K Inhibitor Efficacy in Patients with AR Metastatic Triple-Negative Breast Cancer.
Lehmann BD, Abramson VG, Sanders ME, Mayer EL, Haddad TC, Nanda R, Van Poznak C, Storniolo AM, Nangia JR, Gonzalez-Ericsson PI, Sanchez V, Johnson KN, Abramson RG, Chen SC, Shyr Y, Arteaga CL, Wolff AC, Pietenpol JA, Translational Breast Cancer Research Consortium
(2020) Clin Cancer Res 26: 2111-2123
MeSH Terms: Androgen Receptor Antagonists, Antineoplastic Combined Chemotherapy Protocols, Benzamides, Class I Phosphatidylinositol 3-Kinases, Female, Humans, Imidazoles, Middle Aged, Neoplasm Metastasis, Nitriles, Oxazepines, Phenylthiohydantoin, Protein Kinase Inhibitors, Receptors, Androgen, Survival Rate, Triple Negative Breast Neoplasms
Added March 30, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
Combined CB2 receptor agonist and photodynamic therapy synergistically inhibit tumor growth in triple negative breast cancer.
Zhang J, Zhang S, Liu Y, Su M, Ling X, Liu F, Ge Y, Bai M
(2018) Photodiagnosis Photodyn Ther 24: 185-191
MeSH Terms: Acetamides, Animals, Apoptosis, Cell Line, Tumor, Cell Proliferation, Cell Survival, Combined Modality Therapy, Female, Gene Expression Regulation, Neoplastic, Humans, Indoles, Mice, Neoplasm Recurrence, Local, Phenyl Ethers, Photochemotherapy, Photosensitizing Agents, Quality of Life, Receptor, Cannabinoid, CB2, Receptors, GABA, Singlet Oxygen, Triple Negative Breast Neoplasms, Xenograft Model Antitumor Assays
Added April 2, 2019
0 Communities
1 Members
0 Resources
22 MeSH Terms
Genetic and Phenotypic Diversification of Heterogeneous Tumor Populations.
Elion DL, Cook RS
(2018) Trends Mol Med 24: 655-656
MeSH Terms: Antineoplastic Combined Chemotherapy Protocols, Drug Resistance, Neoplasm, Humans, Neoadjuvant Therapy, Triple Negative Breast Neoplasms
Added April 15, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Gene expression in triple-negative breast cancer in relation to survival.
Wang S, Beeghly-Fadiel A, Cai Q, Cai H, Guo X, Shi L, Wu J, Ye F, Qiu Q, Zheng Y, Zheng W, Bao PP, Shu XO
(2018) Breast Cancer Res Treat 171: 199-207
MeSH Terms: Adult, Aged, Biomarkers, Tumor, Female, Gene Expression, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Humans, Middle Aged, Neoplasm Grading, Neoplasm Staging, Population Surveillance, Prognosis, Registries, Survival Analysis, Triple Negative Breast Neoplasms
Added December 6, 2018
0 Communities
1 Members
0 Resources
16 MeSH Terms
Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival.
Werfel TA, Wang S, Jackson MA, Kavanaugh TE, Joly MM, Lee LH, Hicks DJ, Sanchez V, Ericsson PG, Kilchrist KV, Dimobi SC, Sarett SM, Brantley-Sieders DM, Cook RS, Duvall CL
(2018) Cancer Res 78: 1845-1858
MeSH Terms: Animals, Antineoplastic Agents, Cell Proliferation, Cell Survival, Disease Models, Animal, Female, Humans, Lapatinib, Mechanistic Target of Rapamycin Complex 2, Mice, Mice, Inbred BALB C, Mice, Nude, Nanoparticles, Protein Kinase Inhibitors, RNA, Small Interfering, Rapamycin-Insensitive Companion of mTOR Protein, Receptor, ErbB-2, Triple Negative Breast Neoplasms, Xenograft Model Antitumor Assays
Added March 14, 2018
0 Communities
2 Members
0 Resources
19 MeSH Terms
Biomarkers for assessing the effectiveness of immunotherapy in breast cancer.
Nixon MJ, Balko JM
(2018) Biomark Med 12: 97-100
MeSH Terms: B7-H1 Antigen, Biomarkers, Tumor, Breast Neoplasms, CTLA-4 Antigen, Female, Humans, Immunotherapy, Ipilimumab, Triple Negative Breast Neoplasms
Added March 14, 2018
0 Communities
1 Members
0 Resources
9 MeSH Terms
MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation.
Lee KM, Giltnane JM, Balko JM, Schwarz LJ, Guerrero-Zotano AL, Hutchinson KE, Nixon MJ, Estrada MV, Sánchez V, Sanders ME, Lee T, Gómez H, Lluch A, Pérez-Fidalgo JA, Wolf MM, Andrejeva G, Rathmell JC, Fesik SW, Arteaga CL
(2017) Cell Metab 26: 633-647.e7
MeSH Terms: Animals, Cell Line, Tumor, Drug Resistance, Neoplasm, Female, Humans, Mice, Nude, Mitochondria, Myeloid Cell Leukemia Sequence 1 Protein, Neoplastic Stem Cells, Oxidative Phosphorylation, Proto-Oncogene Proteins c-myc, Reactive Oxygen Species, Triple Negative Breast Neoplasms
Added March 14, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer.
Dushyanthen S, Teo ZL, Caramia F, Savas P, Mintoff CP, Virassamy B, Henderson MA, Luen SJ, Mansour M, Kershaw MH, Trapani JA, Neeson PJ, Salgado R, McArthur GA, Balko JM, Beavis PA, Darcy PK, Loi S
(2017) Nat Commun 8: 606
MeSH Terms: 4-1BB Ligand, Animals, Breast Neoplasms, Cell Line, Tumor, Cell Proliferation, Female, Humans, Immunotherapy, Lymphocytes, Tumor-Infiltrating, MAP Kinase Kinase 1, MAP Kinase Kinase 2, MAP Kinase Signaling System, Mammary Neoplasms, Animal, Mice, OX40 Ligand, Protein Kinase Inhibitors, Pyridones, Pyrimidinones, T-Lymphocyte Subsets, T-Lymphocytes, Triple Negative Breast Neoplasms
Added March 14, 2018
0 Communities
1 Members
0 Resources
21 MeSH Terms
A Predictive Mathematical Modeling Approach for the Study of Doxorubicin Treatment in Triple Negative Breast Cancer.
McKenna MT, Weis JA, Barnes SL, Tyson DR, Miga MI, Quaranta V, Yankeelov TE
(2017) Sci Rep 7: 5725
MeSH Terms: Antibiotics, Antineoplastic, Biostatistics, Cell Line, Tumor, Doxorubicin, Humans, Longitudinal Studies, Models, Biological, Models, Theoretical, Treatment Outcome, Triple Negative Breast Neoplasms
Added July 23, 2018
0 Communities
1 Members
0 Resources
10 MeSH Terms