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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 83

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Protein kinase A-mediated phosphorylation of naked cuticle homolog 2 stimulates cell-surface delivery of transforming growth factor-α for epidermal growth factor receptor transactivation.
Cao Z, Singh B, Li C, Markham NO, Carrington LJ, Franklin JL, Graves-Deal R, Kennedy EJ, Goldenring JR, Coffey RJ
(2019) Traffic 20: 357-368
MeSH Terms: A Kinase Anchor Proteins, Adaptor Proteins, Signal Transducing, Animals, Caco-2 Cells, Calcium-Binding Proteins, Cell Cycle Proteins, Cell Membrane, Cyclic AMP-Dependent Protein Kinases, Dinoprostone, Dogs, ErbB Receptors, HEK293 Cells, Humans, Madin Darby Canine Kidney Cells, Protein Transport, Signal Transduction, Transforming Growth Factor alpha, Vasoactive Intestinal Peptide
Added March 3, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
Inhibition of Epidermal Growth Factor Receptor Activation Is Associated With Improved Diabetic Nephropathy and Insulin Resistance in Type 2 Diabetes.
Li Z, Li Y, Overstreet JM, Chung S, Niu A, Fan X, Wang S, Wang Y, Zhang MZ, Harris RC
(2018) Diabetes 67: 1847-1857
MeSH Terms: Albuminuria, Animals, Biomarkers, Crosses, Genetic, Cytokines, Diabetes Mellitus, Type 2, Diabetic Nephropathies, ErbB Receptors, Erlotinib Hydrochloride, Fibrosis, Glomerulonephritis, Hypoglycemic Agents, Insulin Resistance, Kidney, Macrophages, Membrane Transport Modulators, Mice, Knockout, Mice, Mutant Strains, Nitric Oxide Synthase Type III, Oxidative Stress, Protein Kinase Inhibitors, T-Lymphocytes, Transforming Growth Factor alpha
Added November 9, 2018
1 Communities
0 Members
0 Resources
23 MeSH Terms
Altered TGF-α/β signaling drives cooperation between breast cancer cell populations.
Franco OE, Tyson DR, Konvinse KC, Udyavar AR, Estrada L, Quaranta V, Crawford SE, Hayward SW
(2016) FASEB J 30: 3441-3452
MeSH Terms: Animals, Breast Neoplasms, Cell Line, Tumor, Cell Movement, Cell Transformation, Neoplastic, Epithelium, Humans, Mice, SCID, Signal Transduction, Transforming Growth Factor alpha, Transforming Growth Factor beta
Added May 5, 2017
1 Communities
1 Members
0 Resources
11 MeSH Terms
MiR-374a suppresses lung adenocarcinoma cell proliferation and invasion by targeting TGFA gene expression.
Wu H, Liu Y, Shu XO, Cai Q
(2016) Carcinogenesis 37: 567-75
MeSH Terms: 3' Untranslated Regions, Adenocarcinoma, Adenocarcinoma of Lung, Antibodies, Neutralizing, Cell Line, Tumor, Cell Movement, Cell Proliferation, Gene Expression Regulation, Neoplastic, Humans, Lung, Lung Neoplasms, MicroRNAs, Transforming Growth Factor alpha
Added April 3, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
TGFβ loss activates ADAMTS-1-mediated EGF-dependent invasion in a model of esophageal cell invasion.
Le Bras GF, Taylor C, Koumangoye RB, Revetta F, Loomans HA, Andl CD
(2015) Exp Cell Res 330: 29-42
MeSH Terms: ADAM Proteins, ADAMTS1 Protein, Carcinoma, Squamous Cell, Cell Line, Tumor, Cell Movement, Cell Proliferation, Esophageal Neoplasms, Fibroblasts, Heparin-binding EGF-like Growth Factor, Humans, Interleukin-1, Keratinocytes, Nerve Tissue Proteins, Receptors, Immunologic, Receptors, Transforming Growth Factor beta, Transforming Growth Factor alpha, Transforming Growth Factor beta
Added October 13, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
From wavy hair to naked proteins: the role of transforming growth factor alpha in health and disease.
Singh B, Coffey RJ
(2014) Semin Cell Dev Biol 28: 12-21
MeSH Terms: Animals, EGF Family of Proteins, Epidermal Growth Factor, Epithelial Cells, Hair, Humans, Signal Transduction, Transforming Growth Factor alpha
Added March 27, 2014
1 Communities
2 Members
0 Resources
8 MeSH Terms
Novel mechanistic insights into ectodomain shedding of EGFR Ligands Amphiregulin and TGF-α: impact on gastrointestinal cancers driven by secondary bile acids.
Nagathihalli NS, Beesetty Y, Lee W, Washington MK, Chen X, Lockhart AC, Merchant NB
(2014) Cancer Res 74: 2062-72
MeSH Terms: ADAM Proteins, ADAM17 Protein, Amphiregulin, Bile Acids and Salts, Cyclin D1, Deoxycholic Acid, EGF Family of Proteins, ErbB Receptors, Gastrointestinal Neoplasms, Glycoproteins, HCT116 Cells, Humans, Intercellular Signaling Peptides and Proteins, Pancreas, Phosphorylation, Receptors, G-Protein-Coupled, STAT3 Transcription Factor, Transforming Growth Factor alpha, src-Family Kinases
Added February 14, 2014
0 Communities
3 Members
0 Resources
19 MeSH Terms
A Lactobacillus rhamnosus GG-derived soluble protein, p40, stimulates ligand release from intestinal epithelial cells to transactivate epidermal growth factor receptor.
Yan F, Liu L, Dempsey PJ, Tsai YH, Raines EW, Wilson CL, Cao H, Cao Z, Liu L, Polk DB
(2013) J Biol Chem 288: 30742-30751
MeSH Terms: ADAM Proteins, ADAM17 Protein, Animals, Bacterial Proteins, Cell Line, Tumor, Enzyme Activation, Epithelial Cells, ErbB Receptors, Gene Expression Regulation, Enzymologic, Gene Knockdown Techniques, Heparin-binding EGF-like Growth Factor, Humans, Intercellular Signaling Peptides and Proteins, Intestinal Mucosa, Lactobacillus rhamnosus, Mice, Mice, Knockout, Probiotics, Proto-Oncogene Proteins c-akt, Transcriptional Activation, Transforming Growth Factor alpha, Up-Regulation
Added May 19, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Pierre Ménétrier and his disease.
Coffey RJ, Tanksley J
(2012) Trans Am Clin Climatol Assoc 123: 126-33; discussion 133-4
MeSH Terms: ErbB Receptors, France, Gastritis, Hypertrophic, History, 19th Century, History, 20th Century, History, 21st Century, Transforming Growth Factor alpha
Added March 7, 2014
1 Communities
1 Members
0 Resources
7 MeSH Terms
Amphiregulin exosomes increase cancer cell invasion.
Higginbotham JN, Demory Beckler M, Gephart JD, Franklin JL, Bogatcheva G, Kremers GJ, Piston DW, Ayers GD, McConnell RE, Tyska MJ, Coffey RJ
(2011) Curr Biol 21: 779-86
MeSH Terms: Amphiregulin, Animals, Cell Line, Tumor, Centrifugation, Dogs, EGF Family of Proteins, Electrophoresis, Polyacrylamide Gel, Enzyme-Linked Immunosorbent Assay, ErbB Receptors, Exosomes, Glycoproteins, Heparin-binding EGF-like Growth Factor, Humans, Immunoblotting, Intercellular Signaling Peptides and Proteins, Microscopy, Electron, Neoplasm Invasiveness, Signal Transduction, Transforming Growth Factor alpha
Added December 6, 2012
2 Communities
5 Members
0 Resources
19 MeSH Terms