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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 160

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An analysis of genetically regulated gene expression and the role of co-expression networks across 16 psychiatric and substance use phenotypes.
Gerring ZF, Thorp JG, Gamazon ER, Derks EM
(2022) Eur J Hum Genet 30: 560-566
MeSH Terms: Autism Spectrum Disorder, Child, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Phenotype, Polymorphism, Single Nucleotide, Substance-Related Disorders, Transcriptome
Added March 21, 2022
0 Communities
1 Members
0 Resources
9 MeSH Terms
A transcriptome-wide association study identifies novel candidate susceptibility genes for prostate cancer risk.
Liu D, Zhu J, Zhou D, Nikas EG, Mitanis NT, Sun Y, Wu C, Mancuso N, Cox NJ, Wang L, Freedland SJ, Haiman CA, Gamazon ER, Nikas JB, Wu L
(2022) Int J Cancer 150: 80-90
MeSH Terms: Biomarkers, Tumor, Case-Control Studies, DNA Methylation, Epigenesis, Genetic, Follow-Up Studies, Gene Expression Regulation, Neoplastic, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Male, Polymorphism, Single Nucleotide, Prognosis, Prostatic Neoplasms, Quantitative Trait Loci, Transcriptome, United States
Added October 8, 2021
0 Communities
1 Members
0 Resources
16 MeSH Terms
A transcriptome-wide association study of Alzheimer's disease using prediction models of relevant tissues identifies novel candidate susceptibility genes.
Sun Y, Zhu J, Zhou D, Canchi S, Wu C, Cox NJ, Rissman RA, Gamazon ER, Wu L
(2021) Genome Med 13: 141
MeSH Terms: Alleles, Alzheimer Disease, Chromosome Mapping, Computational Biology, Databases, Genetic, Gene Expression Profiling, Gene Expression Regulation, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Models, Biological, Organ Specificity, Polymorphism, Single Nucleotide, Prognosis, Resorcinols, Signal Transduction, Transcriptome
Added October 8, 2021
0 Communities
1 Members
0 Resources
17 MeSH Terms
A transcriptome-wide association study identifies novel blood-based gene biomarker candidates for Alzheimer's disease risk.
Sun Y, Zhou D, Rahman MR, Zhu J, Ghoneim D, Cox NJ, Beach TG, Wu C, Gamazon ER, Wu L
(2021) Hum Mol Genet 31: 289-299
MeSH Terms: Alzheimer Disease, Genetic Markers, Genome-Wide Association Study, Humans, Polymorphism, Single Nucleotide, Quality of Life, Transcriptome
Added October 8, 2021
0 Communities
1 Members
0 Resources
7 MeSH Terms
Metabolic alterations mediated by STAT3 promotes drug persistence in CML.
Patel SB, Nemkov T, Stefanoni D, Benavides GA, Bassal MA, Crown BL, Matkins VR, Camacho V, Kuznetsova V, Hoang AT, Tenen DE, Wolock SL, Park J, Ying L, Yue Z, Chen JY, Yang H, Tenen DG, Ferrell PB, Lu R, Darley-Usmar V, D'Alessandro A, Bhatia R, Welner RS
(2021) Leukemia 35: 3371-3382
MeSH Terms: Animals, Apoptosis, Drug Resistance, Neoplasm, Female, Glycolysis, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Male, Metabolome, Mice, Neoplastic Stem Cells, Protein Kinase Inhibitors, STAT3 Transcription Factor, Small Molecule Libraries, Transcriptome
Added September 1, 2022
0 Communities
1 Members
0 Resources
MeSH Terms
KCNK3 Mutation Causes Altered Immune Function in Pulmonary Arterial Hypertension Patients and Mouse Models.
West JD, Austin ED, Rizzi EM, Yan L, Tanjore H, Crabtree AL, Moore CS, Muthian G, Carrier EJ, Jacobson DA, Hamid R, Kendall PL, Majka S, Rathinasabapathy A
(2021) Int J Mol Sci 22:
MeSH Terms: Animals, Biomarkers, Case-Control Studies, Cytokines, Disease Models, Animal, Disease Susceptibility, Gene Expression Profiling, Genetic Predisposition to Disease, Humans, Hypoxia, Immunomodulation, Lymphocytes, Mice, Mice, Knockout, Models, Biological, Monocytes, Mutation, Nerve Tissue Proteins, Potassium Channels, Tandem Pore Domain, Pulmonary Arterial Hypertension, Transcriptome
Added June 14, 2021
0 Communities
1 Members
0 Resources
21 MeSH Terms
Multilayer modelling of the human transcriptome and biological mechanisms of complex diseases and traits.
Azevedo T, Dimitri GM, Lió P, Gamazon ER
(2021) NPJ Syst Biol Appl 7: 24
MeSH Terms: Gene Regulatory Networks, Genomics, Humans, Organ Specificity, Phenotype, Transcriptome
Added May 30, 2021
0 Communities
1 Members
0 Resources
6 MeSH Terms
Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease.
de Goede OM, Nachun DC, Ferraro NM, Gloudemans MJ, Rao AS, Smail C, Eulalio TY, Aguet F, Ng B, Xu J, Barbeira AN, Castel SE, Kim-Hellmuth S, Park Y, Scott AJ, Strober BJ, GTEx Consortium, Brown CD, Wen X, Hall IM, Battle A, Lappalainen T, Im HK, Ardlie KG, Mostafavi S, Quertermous T, Kirkegaard K, Montgomery SB
(2021) Cell 184: 2633-2648.e19
MeSH Terms: Coronary Artery Disease, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Disease, Gene Expression Profiling, Genetic Variation, Humans, Inflammatory Bowel Diseases, Multifactorial Inheritance, Organ Specificity, Population, Quantitative Trait Loci, RNA, Long Noncoding, Transcriptome
Added April 18, 2021
0 Communities
1 Members
0 Resources
14 MeSH Terms
Exploiting the GTEx resources to decipher the mechanisms at GWAS loci.
Barbeira AN, Bonazzola R, Gamazon ER, Liang Y, Park Y, Kim-Hellmuth S, Wang G, Jiang Z, Zhou D, Hormozdiari F, Liu B, Rao A, Hamel AR, Pividori MD, Aguet F, GTEx GWAS Working Group, Bastarache L, Jordan DM, Verbanck M, Do R, GTEx Consortium, Stephens M, Ardlie K, McCarthy M, Montgomery SB, Segrè AV, Brown CD, Lappalainen T, Wen X, Im HK
(2021) Genome Biol 22: 49
MeSH Terms: Gene Expression, Genes, Genetic Predisposition to Disease, Genome-Wide Association Study, Genotype, Humans, Multifactorial Inheritance, Transcriptome
Added February 3, 2021
0 Communities
1 Members
0 Resources
8 MeSH Terms
Neoadjuvant pazopanib and molecular analysis of tissue response in renal cell carcinoma.
Wood CG, Ferguson JE, Parker JS, Moore DT, Whisenant JG, Maygarden SJ, Wallen EM, Kim WY, Milowsky MI, Beckermann KE, Davis NB, Haake SM, Karam JA, Bortone DS, Vincent BG, Powles T, Rathmell WK
(2020) JCI Insight 5:
MeSH Terms: Adult, Aged, Angiogenesis Inhibitors, Biomarkers, Tumor, Carcinoma, Renal Cell, Case-Control Studies, Female, Follow-Up Studies, Humans, Indazoles, Kidney Neoplasms, Male, Middle Aged, Neoadjuvant Therapy, Prognosis, Pyrimidines, Retrospective Studies, Sulfonamides, Survival Rate, Transcriptome
Added April 27, 2021
0 Communities
1 Members
0 Resources
20 MeSH Terms