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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 11

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Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP.
Byndloss MX, Tsai AY, Walker GT, Miller CN, Young BM, English BC, Seyffert N, Kerrinnes T, de Jong MF, Atluri VL, Winter MG, Celli J, Tsolis RM
(2019) mBio 10:
MeSH Terms: Animals, Brucella abortus, Cell Death, Endoplasmic Reticulum Stress, Female, Mice, Mice, Inbred C57BL, Nod1 Signaling Adaptor Protein, Nod2 Signaling Adaptor Protein, Placenta, Pregnancy, Transcription Factor CHOP, Trophoblasts, Type IV Secretion Systems, Unfolded Protein Response
Added March 30, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation.
He K, Zheng X, Li M, Zhang L, Yu J
(2016) Oncogene 35: 148-57
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Antineoplastic Agents, Apoptosis, Cell Cycle Proteins, Cell Line, Tumor, Colonic Neoplasms, Everolimus, Female, Humans, Mice, Nude, Phosphoproteins, Phosphorylation, Protein Kinase Inhibitors, Receptors, TNF-Related Apoptosis-Inducing Ligand, Sirolimus, TOR Serine-Threonine Kinases, Transcription Factor CHOP, Xenograft Model Antitumor Assays
Added July 28, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Trafficking-deficient mutant GABRG2 subunit amount may modify epilepsy phenotype.
Kang JQ, Shen W, Macdonald RL
(2013) Ann Neurol 74: 547-59
MeSH Terms: Animals, Cell Line, Transformed, Codon, Nonsense, Disease Models, Animal, Endoplasmic Reticulum, Epilepsy, Gene Expression Regulation, Genotype, Glycosylation, Humans, Mice, Mice, Transgenic, Models, Molecular, Mutagenesis, Phenotype, Protein Subunits, Protein Transport, Receptors, GABA-A, Transcription Factor CHOP, Transfection, Ubiquitin
Added January 24, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling.
Oh YT, Yue P, Zhou W, Balko JM, Black EP, Owonikoko TK, Khuri FR, Sun SY
(2012) J Biol Chem 287: 257-267
MeSH Terms: Cell Line, Tumor, Extracellular Signal-Regulated MAP Kinases, Gene Expression Regulation, Neoplastic, Humans, JNK Mitogen-Activated Protein Kinases, Mutation, Promoter Regions, Genetic, Proto-Oncogene Proteins B-raf, Receptors, TNF-Related Apoptosis-Inducing Ligand, Ribosomal Protein S6 Kinases, Signal Transduction, Transcription Factor CHOP, Transcription, Genetic, ets-Domain Protein Elk-1, ras Proteins
Added March 10, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eIF2a-mediated decrease in type 2 deiodinase synthesis.
Arrojo E Drigo R, Fonseca TL, Castillo M, Salathe M, Simovic G, Mohácsik P, Gereben B, Bianco AC
(2011) Mol Endocrinol 25: 2065-75
MeSH Terms: Animals, Cell Line, Cystic Fibrosis, Down-Regulation, Endoplasmic Reticulum Stress, Epithelial Cells, Eukaryotic Initiation Factor-2, Gene Expression, Humans, Iodide Peroxidase, Mice, Proteasome Endopeptidase Complex, Protein Stability, Proteolysis, Respiratory Mucosa, Signal Transduction, Thapsigargin, Thyroxine, Transcription Factor CHOP, Triiodothyronine, Tunicamycin
Added April 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Phosphatidylethanolamines modified by γ-ketoaldehyde (γKA) induce endoplasmic reticulum stress and endothelial activation.
Guo L, Chen Z, Cox BE, Amarnath V, Epand RF, Epand RM, Davies SS
(2011) J Biol Chem 286: 18170-80
MeSH Terms: Cell Adhesion Molecules, Cell Line, Cell Membrane, Chemokine CCL2, Endoplasmic Reticulum, Endothelial Cells, Heat-Shock Proteins, Humans, Interleukin-8, Lipid Bilayers, Lipid Peroxidation, Phosphatidylethanolamines, Transcription Factor CHOP, Unfolded Protein Response
Added June 1, 2013
1 Communities
1 Members
0 Resources
14 MeSH Terms
Ecteinascidin 743 interferes with the activity of EWS-FLI1 in Ewing sarcoma cells.
Grohar PJ, Griffin LB, Yeung C, Chen QR, Pommier Y, Khanna C, Khan J, Helman LJ
(2011) Neoplasia 13: 145-53
MeSH Terms: Antineoplastic Agents, Alkylating, Bone Neoplasms, Cell Line, Tumor, Child, DAX-1 Orphan Nuclear Receptor, Dioxoles, Europe, Gene Expression Regulation, Neoplastic, Humans, Oncogene Proteins, Fusion, Promoter Regions, Genetic, Proto-Oncogene Protein c-fli-1, RNA-Binding Protein EWS, RNA-Binding Protein FUS, Sarcoma, Sarcoma, Ewing, Tetrahydroisoquinolines, Trabectedin, Transcription Factor CHOP
Added September 3, 2013
0 Communities
2 Members
0 Resources
19 MeSH Terms
Myc-mediated transcriptional repression by recruitment of histone deacetylase.
Kurland JF, Tansey WP
(2008) Cancer Res 68: 3624-9
MeSH Terms: Animals, Apoptosis, Cell Cycle Proteins, Cell Proliferation, Chromatin Immunoprecipitation, Gene Expression Regulation, Neoplastic, Histone Deacetylases, Inhibitor of Differentiation Protein 2, Models, Biological, Protein Structure, Tertiary, Proto-Oncogene Proteins c-myc, Rats, Transcription Factor CHOP, Transcription, Genetic
Added March 10, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response.
Jiang HY, Wek SA, McGrath BC, Lu D, Hai T, Harding HP, Wang X, Ron D, Cavener DR, Wek RC
(2004) Mol Cell Biol 24: 1365-77
MeSH Terms: Activating Transcription Factor 3, Activating Transcription Factor 4, Animals, CCAAT-Enhancer-Binding Proteins, Eukaryotic Initiation Factor-2, Mice, Phosphorylation, Phosphotransferases, Protein Kinases, Protein-Serine-Threonine Kinases, RNA, Messenger, Transcription Factor CHOP, Transcription Factors, eIF-2 Kinase
Added August 13, 2010
1 Communities
0 Members
0 Resources
14 MeSH Terms
Induction of the C/EBP homologous protein (CHOP) by amino acid deprivation requires insulin-like growth factor I, phosphatidylinositol 3-kinase, and mammalian target of rapamycin signaling.
Entingh AJ, Law BK, Moses HL
(2001) Endocrinology 142: 221-8
MeSH Terms: 3T3 Cells, Amino Acids, Androstadienes, Animals, Arsenites, CCAAT-Enhancer-Binding Proteins, Calcimycin, Cell Line, Chromones, Culture Media, Dimerization, Enzyme Inhibitors, Gene Expression Regulation, Hydrogen Peroxide, Insulin-Like Growth Factor I, Mammals, Mice, Morpholines, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Signal Transduction, Sirolimus, Sodium Compounds, Transcription Factor CHOP, Transcription Factors, Transcription, Genetic, Wortmannin
Added February 17, 2014
0 Communities
1 Members
0 Resources
27 MeSH Terms