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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 51

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Apoptosis signal-regulating kinase 1 (ASK1) inhibition reduces endothelial cytokine production without improving permeability after toll-like receptor 4 (TLR4) challenge.
Miller MR, Koch SR, Choi H, Lamb FS, Stark RJ
(2021) Transl Res 235: 115-128
MeSH Terms: Cells, Cultured, Cytokines, Endothelial Cells, Humans, JNK Mitogen-Activated Protein Kinases, MAP Kinase Kinase Kinase 5, MAP Kinase Signaling System, Nitric Oxide Synthase Type III, Permeability, Toll-Like Receptor 4, p38 Mitogen-Activated Protein Kinases
Added April 16, 2021
0 Communities
1 Members
0 Resources
11 MeSH Terms
Immunobiology and application of toll-like receptor 4 agonists to augment host resistance to infection.
Hernandez A, Patil NK, Stothers CL, Luan L, McBride MA, Owen AM, Burelbach KR, Williams DL, Sherwood ER, Bohannon JK
(2019) Pharmacol Res 150: 104502
MeSH Terms: Adjuvants, Immunologic, Animals, Disease Resistance, Humans, Immunity, Innate, Infection Control, Infections, Toll-Like Receptor 4
Added December 1, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
S100 Proteins in the Innate Immune Response to Pathogens.
Kozlyuk N, Monteith AJ, Garcia V, Damo SM, Skaar EP, Chazin WJ
(2019) Methods Mol Biol 1929: 275-290
MeSH Terms: Calcium, Host-Pathogen Interactions, Humans, Immunity, Innate, Inflammation, Manganese, Models, Molecular, Protein Conformation, S100 Proteins, Toll-Like Receptor 4
Added March 26, 2019
0 Communities
2 Members
0 Resources
10 MeSH Terms
Graphene oxide polarizes iNKT cells for production of TGFβ and attenuates inflammation in an iNKT cell-mediated sepsis model.
Lee SW, Park HJ, Van Kaer L, Hong S, Hong S
(2018) Sci Rep 8: 10081
MeSH Terms: Animals, Antigens, CD1d, Cell Polarity, Dendritic Cells, Disease Models, Animal, Galactosylceramides, Graphite, Humans, Inflammation, Intraepithelial Lymphocytes, Lymphocyte Activation, Mice, Nanotubes, Carbon, Natural Killer T-Cells, Sepsis, Toll-Like Receptor 4, Transforming Growth Factor beta
Added March 26, 2019
0 Communities
1 Members
0 Resources
17 MeSH Terms
The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism.
Fensterheim BA, Young JD, Luan L, Kleinbard RR, Stothers CL, Patil NK, McAtee-Pereira AG, Guo Y, Trenary I, Hernandez A, Fults JB, Williams DL, Sherwood ER, Bohannon JK
(2018) J Immunol 200: 3777-3789
MeSH Terms: Adenosine Triphosphate, Animals, Candida albicans, Candidiasis, Glycolysis, Lipid A, Macrophages, Male, Mice, Mice, Inbred C57BL, Myeloid Differentiation Factor 88, Signal Transduction, Staphylococcal Infections, Staphylococcus aureus, TOR Serine-Threonine Kinases, Toll-Like Receptor 4
Added March 28, 2019
0 Communities
3 Members
0 Resources
16 MeSH Terms
Neuroinflammation Alters Integrative Properties of Rat Hippocampal Pyramidal Cells.
Frigerio F, Flynn C, Han Y, Lyman K, Lugo JN, Ravizza T, Ghestem A, Pitsch J, Becker A, Anderson AE, Vezzani A, Chetkovich D, Bernard C
(2018) Mol Neurobiol 55: 7500-7511
MeSH Terms: Animals, Dendrites, Down-Regulation, Hippocampus, Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels, Inflammation, Lipopolysaccharides, Male, Membrane Proteins, Microglia, Potassium Channels, Pyramidal Cells, Rats, Sprague-Dawley, Time Factors, Toll-Like Receptor 4
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Endothelial nitric oxide synthase modulates Toll-like receptor 4-mediated IL-6 production and permeability via nitric oxide-independent signaling.
Stark RJ, Koch SR, Choi H, Mace EH, Dikalov SI, Sherwood ER, Lamb FS
(2018) FASEB J 32: 945-956
MeSH Terms: Capillary Permeability, Cells, Cultured, Chronic Disease, Endothelial Cells, Gene Expression Regulation, Enzymologic, Humans, Imidazoles, Interleukin-6, Lipopolysaccharides, MAP Kinase Signaling System, Nitric Oxide, Nitric Oxide Synthase Type III, Pyridines, Toll-Like Receptor 4, Vasculitis, p38 Mitogen-Activated Protein Kinases
Added October 27, 2017
0 Communities
3 Members
0 Resources
16 MeSH Terms
Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus.
Karimy JK, Zhang J, Kurland DB, Theriault BC, Duran D, Stokum JA, Furey CG, Zhou X, Mansuri MS, Montejo J, Vera A, DiLuna ML, Delpire E, Alper SL, Gunel M, Gerzanich V, Medzhitov R, Simard JM, Kahle KT
(2017) Nat Med 23: 997-1003
MeSH Terms: Acetazolamide, Animals, Antioxidants, Blotting, Western, Bumetanide, Cerebral Hemorrhage, Cerebral Ventricles, Cerebrospinal Fluid, Choroid Plexus, Diuretics, Gene Knockdown Techniques, Gene Knockout Techniques, Hydrocephalus, Immunoblotting, Immunohistochemistry, Immunoprecipitation, Inflammation, NF-kappa B, Proline, Protein Serine-Threonine Kinases, Rats, Rats, Wistar, Salicylanilides, Solute Carrier Family 12, Member 2, Sulfonamides, Thiocarbamates, Toll-Like Receptor 4
Added April 3, 2018
0 Communities
1 Members
0 Resources
27 MeSH Terms
Comparative Transcriptome Profiles of Human Blood in Response to the Toll-like Receptor 4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A.
Luan L, Patil NK, Guo Y, Hernandez A, Bohannon JK, Fensterheim BA, Wang J, Xu Y, Enkhbaatar P, Stark R, Sherwood ER
(2017) Sci Rep 7: 40050
MeSH Terms: Adjuvants, Immunologic, Healthy Volunteers, Humans, Immunologic Factors, Leukocytes, Lipid A, Lipopolysaccharides, Microarray Analysis, Toll-Like Receptor 4, Transcriptome
Added April 6, 2017
0 Communities
3 Members
0 Resources
10 MeSH Terms
IRF3 promotes adipose inflammation and insulin resistance and represses browning.
Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, Tenen D, Roh HC, Kong X, Kazak L, Ahmad R, Rosen ED
(2016) J Clin Invest 126: 2839-54
MeSH Terms: 3T3-L1 Cells, Adipocytes, Adipose Tissue, Adiposity, Adult, Animals, Blood Glucose, Diet, Female, Gene Expression Regulation, Glucose Clamp Technique, Glucose Transporter Type 4, HEK293 Cells, Homeostasis, Humans, Inflammation, Insulin Resistance, Interferon Regulatory Factor-3, Male, Mice, Mice, Transgenic, Middle Aged, NF-kappa B, Obesity, Toll-Like Receptor 3, Toll-Like Receptor 4
Added May 16, 2019
0 Communities
1 Members
0 Resources
MeSH Terms