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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 41

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Suboptimal inhibition of platelet cyclooxygenase 1 by aspirin in systemic lupus erythematosus: association with metabolic syndrome.
Kawai VK, Avalos I, Oeser A, Oates JA, Milne GL, Solus JF, Chung CP, Stein CM
(2014) Arthritis Care Res (Hoboken) 66: 285-92
MeSH Terms: Adult, Aspirin, Biomarkers, Blood Platelets, C-Reactive Protein, Chi-Square Distribution, Cyclooxygenase 1, Cyclooxygenase Inhibitors, Female, Humans, Lupus Erythematosus, Systemic, Male, Metabolic Syndrome, Middle Aged, Obesity, Prospective Studies, Thromboxane B2, Time Factors, Treatment Outcome
Added March 7, 2014
2 Communities
1 Members
0 Resources
19 MeSH Terms
Suboptimal inhibition of platelet cyclooxygenase-1 by aspirin in metabolic syndrome.
Smith JP, Haddad EV, Taylor MB, Oram D, Blakemore D, Chen Q, Boutaud O, Oates JA
(2012) Hypertension 59: 719-25
MeSH Terms: Aged, Aspirin, Blood Platelets, Cardiovascular Diseases, Cyclooxygenase 1, Cyclooxygenase Inhibitors, Dose-Response Relationship, Drug, Female, Follow-Up Studies, Gas Chromatography-Mass Spectrometry, Humans, Male, Metabolic Syndrome, Middle Aged, Platelet Aggregation, Prospective Studies, Thromboxane B2, Treatment Outcome
Added March 27, 2014
1 Communities
2 Members
0 Resources
18 MeSH Terms
Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes.
Boutaud O, Oates JA
(2010) Methods Mol Biol 644: 67-90
MeSH Terms: Acetaminophen, Animals, Arachidonic Acid, Aspirin, Blood Platelets, Cell Line, Tumor, Cyclooxygenase Inhibitors, Dinoprostone, Gas Chromatography-Mass Spectrometry, Humans, Hydrogen Peroxide, Mice, Oxidation-Reduction, Prostaglandin-Endoperoxide Synthases, Salicylic Acid, Thromboxane B2
Added March 7, 2014
1 Communities
2 Members
0 Resources
16 MeSH Terms
Elevated ratio of urinary metabolites of thromboxane and prostacyclin is associated with adverse cardiovascular events in ADAPT.
Montine TJ, Sonnen JA, Milne G, Baker LD, Breitner JC
(2010) PLoS One 5: e9340
MeSH Terms: 6-Ketoprostaglandin F1 alpha, Aged, Aged, 80 and over, Alzheimer Disease, Anti-Inflammatory Agents, Non-Steroidal, Aspirin, Cardiovascular Diseases, Celecoxib, Drug Therapy, Combination, F2-Isoprostanes, Female, Humans, Male, Naproxen, Pyrazoles, Sulfonamides, Thromboxane B2, Treatment Outcome
Added March 26, 2014
1 Communities
1 Members
0 Resources
18 MeSH Terms
Low concentrations of reactive gamma-ketoaldehydes prime thromboxane-dependent human platelet aggregation via p38-MAPK activation.
Bernoud-Hubac N, Alam DA, Lefils J, Davies SS, Amarnath V, Guichardant M, Roberts LJ, Lagarde M
(2009) Biochim Biophys Acta 1791: 307-13
MeSH Terms: Blood Platelets, Blotting, Western, Collagen, Cytosol, Humans, Isoprostanes, MAP Kinase Kinase Kinases, Phospholipases A2, Phosphorylation, Platelet Activation, Platelet Aggregation, Prostaglandins E, Proto-Oncogene Proteins, Pyridoxamine, Thromboxane B2, Vitamin B Complex
Added June 1, 2013
1 Communities
1 Members
0 Resources
16 MeSH Terms
Hyperacute lung rejection in the pig-to-human model. III. Platelet receptor inhibitors synergistically modulate complement activation and lung injury.
Pfeiffer S, Zorn GL, Zhang JP, Giorgio TD, Robson SC, Azimzadeh AM, Pierson RN
(2003) Transplantation 75: 953-9
MeSH Terms: Acute Disease, Animals, Aurintricarboxylic Acid, Blood Physiological Phenomena, Blood Platelets, Complement Activation, Dipeptides, Drug Synergism, Graft Rejection, Graft Survival, Hematocrit, Histamine, Humans, Lung, Lung Transplantation, Platelet Glycoprotein GPIIb-IIIa Complex, Platelet Glycoprotein GPIb-IX Complex, Platelet Membrane Glycoproteins, Swine, Thrombin, Thromboxane B2, Transplantation, Heterologous
Added March 20, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Inhibition of endogenous nitric oxide during endotoxemia in awake sheep - effects of Nomega-nitro-l-arginine on the distribution of pulmonary vascular resistance and prostanoid products.
Koizumi T, Johnston D, Bjertnaes LJ, Banerjee MR, Newman JH
(2002) Exp Lung Res 28: 473-84
MeSH Terms: 6-Ketoprostaglandin F1 alpha, Animals, Endotoxemia, Enzyme Inhibitors, Hemodynamics, Nitric Oxide, Nitroarginine, Oxygen, Partial Pressure, Prostaglandins, Pulmonary Circulation, Sheep, Thromboxane B2, Vascular Resistance
Added March 5, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice.
Burleigh ME, Babaev VR, Oates JA, Harris RC, Gautam S, Riendeau D, Marnett LJ, Morrow JD, Fazio S, Linton MF
(2002) Circulation 105: 1816-23
MeSH Terms: Animals, Arteriosclerosis, Blood Platelets, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors, Female, Indomethacin, Isoenzymes, Kinetics, Lactones, Lipids, Liver Transplantation, Macrophages, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Prostaglandin-Endoperoxide Synthases, Prostaglandins, RNA, Messenger, Receptors, LDL, Sulfones, Thromboxane B2
Added December 10, 2013
1 Communities
4 Members
0 Resources
24 MeSH Terms
Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study.
Mills JL, DerSimonian R, Raymond E, Morrow JD, Roberts LJ, Clemens JD, Hauth JC, Catalano P, Sibai B, Curet LB, Levine RJ
(1999) JAMA 282: 356-62
MeSH Terms: 6-Ketoprostaglandin F1 alpha, Adult, Biomarkers, Epoprostenol, Female, Humans, Pre-Eclampsia, Pregnancy, Prospective Studies, Randomized Controlled Trials as Topic, Thromboxane A2, Thromboxane B2
Added December 10, 2013
0 Communities
1 Members
0 Resources
12 MeSH Terms
Increased formation of thromboxane in vivo in humans with mastocytosis.
Morrow JD, Oates JA, Roberts LJ, Zackert WE, Mitchell TA, Lazarus G, Guzzo C
(1999) J Invest Dermatol 113: 93-7
MeSH Terms: 6-Ketoprostaglandin F1 alpha, Adult, Aged, Aspirin, Cyclooxygenase Inhibitors, Female, Humans, Male, Methylhistamines, Middle Aged, Platelet Factor 4, Prostaglandins D, Thromboxane B2, Urticaria Pigmentosa, beta-Thromboglobulin
Added December 10, 2013
0 Communities
2 Members
0 Resources
15 MeSH Terms