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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 10

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Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain.
Cooley CB, Ryno LM, Plate L, Morgan GJ, Hulleman JD, Kelly JW, Wiseman RL
(2014) Proc Natl Acad Sci U S A 111: 13046-51
MeSH Terms: Activating Transcription Factor 6, Amyloid, DNA-Binding Proteins, Extracellular Space, Genes, Reporter, HEK293 Cells, Humans, Immunoglobulin Light Chains, Luciferases, Protein Aggregates, Protein Stability, Proteolysis, Regulatory Factor X Transcription Factors, Stress, Physiological, Thapsigargin, Transcription Factors, Unfolded Protein Response, X-Box Binding Protein 1
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eIF2a-mediated decrease in type 2 deiodinase synthesis.
Arrojo E Drigo R, Fonseca TL, Castillo M, Salathe M, Simovic G, Mohácsik P, Gereben B, Bianco AC
(2011) Mol Endocrinol 25: 2065-75
MeSH Terms: Animals, Cell Line, Cystic Fibrosis, Down-Regulation, Endoplasmic Reticulum Stress, Epithelial Cells, Eukaryotic Initiation Factor-2, Gene Expression, Humans, Iodide Peroxidase, Mice, Proteasome Endopeptidase Complex, Protein Stability, Proteolysis, Respiratory Mucosa, Signal Transduction, Thapsigargin, Thyroxine, Transcription Factor CHOP, Triiodothyronine, Tunicamycin
Added April 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Ionic mechanisms of pacemaker activity in spontaneously contracting atrial HL-1 cells.
Yang Z, Murray KT
(2011) J Cardiovasc Pharmacol 57: 28-36
MeSH Terms: Action Potentials, Biological Clocks, Calcium, Cell Line, Transformed, Diastole, Heart Atria, Humans, Ions, Myocytes, Cardiac, Ryanodine, Sarcolemma, Sarcoplasmic Reticulum, Sinoatrial Node, Thapsigargin
Added January 20, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
The effects of cellular contraction on aortic valve leaflet flexural stiffness.
Merryman WD, Huang HY, Schoen FJ, Sacks MS
(2006) J Biomech 39: 88-96
MeSH Terms: Animals, Aortic Valve, Fibroblasts, In Vitro Techniques, Myocardial Contraction, Myocytes, Smooth Muscle, Potassium Chloride, Stress, Mechanical, Swine, Thapsigargin
Added February 12, 2015
0 Communities
1 Members
0 Resources
10 MeSH Terms
Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses.
Jiang HY, Wek SA, McGrath BC, Scheuner D, Kaufman RJ, Cavener DR, Wek RC
(2003) Mol Cell Biol 23: 5651-63
MeSH Terms: Animals, Apoptosis, Cell Nucleus, Cells, Cultured, Cycloheximide, Dactinomycin, Dose-Response Relationship, Drug, Endoplasmic Reticulum, Enzyme Activation, Eukaryotic Initiation Factor-2, Heterozygote, Immunoblotting, Luciferases, Mice, Microscopy, Confocal, Microscopy, Fluorescence, NF-kappa B, Phosphorylation, Protein Biosynthesis, Protein Synthesis Inhibitors, Protein Transport, Thapsigargin, Transcription, Genetic, Transcriptional Activation
Added August 13, 2010
1 Communities
0 Members
0 Resources
24 MeSH Terms
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs.
Ye J, Rawson RB, Komuro R, Chen X, Davé UP, Prywes R, Brown MS, Goldstein JL
(2000) Mol Cell 6: 1355-64
MeSH Terms: Activating Transcription Factor 6, Amino Acid Motifs, Amino Acid Sequence, Animals, CCAAT-Enhancer-Binding Proteins, Carrier Proteins, Cell Line, DNA-Binding Proteins, Endopeptidases, Endoplasmic Reticulum, Endoplasmic Reticulum Chaperone BiP, Heat-Shock Proteins, Humans, Immunoblotting, Intracellular Membranes, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Molecular Chaperones, Molecular Sequence Data, Mutation, Proprotein Convertases, Protein Binding, Protein Processing, Post-Translational, RNA, Messenger, Sequence Alignment, Serine Endopeptidases, Sterol Regulatory Element Binding Protein 1, Thapsigargin, Transcription Factors, Transcription, Genetic, Tunicamycin
Added March 5, 2014
0 Communities
1 Members
0 Resources
31 MeSH Terms
Protein kinase C activator PMA reduces the Ca(2+) response to antigen stimulation of adherent RBL-2H3 mucosal mast cells by inhibiting depletion of intracellular Ca(2+) stores.
Kuchtey J, Fewtrell C
(1999) J Cell Physiol 181: 113-23
MeSH Terms: Antigens, Calcium, Cell Adhesion, Cell Line, Enzyme Activation, Fluorescent Dyes, Fura-2, Logistic Models, Mast Cells, Patch-Clamp Techniques, Protein Kinase C, Stimulation, Chemical, Tetradecanoylphorbol Acetate, Thapsigargin
Added February 19, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Heterogeneous responses of cell Ca2+ in human airway epithelium.
Paradiso AM, Brown HA, Ye H, Harden TK, Boucher RC
(1999) Exp Lung Res 25: 277-90
MeSH Terms: Adenosine Triphosphate, Adult, Bradykinin, Calcium, Calcium-Transporting ATPases, Cells, Cultured, Epithelial Cells, Female, Fluorescent Antibody Technique, Indirect, Fura-2, Histamine, Humans, Keratins, Male, Nasal Mucosa, Receptors, Purinergic P2, Thapsigargin
Added March 21, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Acute regulation of norepinephrine transport: I. protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells.
Apparsundaram S, Galli A, DeFelice LJ, Hartzell HC, Blakely RD
(1998) J Pharmacol Exp Ther 287: 733-43
MeSH Terms: Biological Transport, Carrier Proteins, Cell Line, Cell Membrane, Egtazic Acid, Enzyme Activation, Methacholine Chloride, Norepinephrine, Norepinephrine Plasma Membrane Transport Proteins, Protein Kinase C, Receptors, Muscarinic, Symporters, Thapsigargin
Added December 10, 2013
1 Communities
2 Members
0 Resources
13 MeSH Terms
Metabotropic glutamate receptor (mGluR)-mediated potentiation of cyclic AMP responses does not require phosphoinositide hydrolysis: mediation by a group II-like mGluR.
Winder DG, Conn PJ
(1995) J Neurochem 64: 592-9
MeSH Terms: Animals, Brain, Calcium, Calcium-Transporting ATPases, Cyclic AMP, Cycloleucine, Glycine, Hydrolysis, In Vitro Techniques, Intracellular Membranes, Neurotoxins, Phosphatidylinositols, Protein Kinase C, Rats, Receptors, Metabotropic Glutamate, Resorcinols, Terpenes, Thapsigargin
Added May 19, 2014
0 Communities
2 Members
0 Resources
18 MeSH Terms