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T-B Lymphocyte Interactions Promote Type 1 Diabetes Independently of SLAM-Associated Protein.
Bonami RH, Nyhoff LE, McNitt DH, Hulbert C, Felton JL, Kendall PL, Thomas JW
(2020) J Immunol 205: 3263-3276
MeSH Terms: Animals, Autoantibodies, B-Lymphocytes, Cell Communication, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 1, Mice, Mice, Inbred NOD, Mice, Transgenic, Signaling Lymphocytic Activation Molecule Associated Protein, Th1 Cells
Added December 1, 2020
1 Communities
0 Members
0 Resources
11 MeSH Terms
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, Newcomb DC, Wells AD, Restifo NP, Rathmell WK, Locasale JW, Davila ML, Blazar BR, Rathmell JC
(2018) Cell 175: 1780-1795.e19
MeSH Terms: Animals, CD8-Positive T-Lymphocytes, Cell Differentiation, Glutaminase, Lymphocyte Activation, Male, Mice, Mice, Transgenic, Th1 Cells, Th17 Cells
Added October 30, 2019
0 Communities
2 Members
0 Resources
MeSH Terms
mPGES1-Dependent Prostaglandin E (PGE) Controls Antigen-Specific Th17 and Th1 Responses by Regulating T Autocrine and Paracrine PGE Production.
Maseda D, Johnson EM, Nyhoff LE, Baron B, Kojima F, Wilhelm AJ, Ward MR, Woodward JG, Brand DD, Crofford LJ
(2018) J Immunol 200: 725-736
MeSH Terms: Animals, Autocrine Communication, Dinoprostone, Epitopes, T-Lymphocyte, Gene Expression Regulation, Immunization, Immunomodulation, Lymphocyte Activation, Mice, Paracrine Communication, Phenotype, Prostaglandin-E Synthases, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Prostaglandin E, EP4 Subtype, Th1 Cells, Th17 Cells
Added March 25, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
In Utero Exposure to Histological Chorioamnionitis Primes the Exometabolomic Profiles of Preterm CD4 T Lymphocytes.
Matta P, Sherrod SD, Marasco CC, Moore DJ, McLean JA, Weitkamp JH
(2017) J Immunol 199: 3074-3085
MeSH Terms: Biomarkers, Chorioamnionitis, Enterotoxins, Female, Humans, Infant, Newborn, Infant, Premature, Male, Pregnancy, Th1 Cells
Added September 28, 2017
1 Communities
3 Members
0 Resources
10 MeSH Terms
Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4+ T Cell Responses.
da Silva Antunes R, Paul S, Sidney J, Weiskopf D, Dan JM, Phillips E, Mallal S, Crotty S, Sette A, Lindestam Arlehamn CS
(2017) PLoS One 12: e0169086
MeSH Terms: Adult, Epitope Mapping, Epitopes, T-Lymphocyte, Female, Humans, Immunoassay, Immunologic Memory, Male, Tetanus Toxoid, Th1 Cells, Th2 Cells
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection.
Hardbower DM, Asim M, Murray-Stewart T, Casero RA, Verriere T, Lewis ND, Chaturvedi R, Piazuelo MB, Wilson KT
(2016) Amino Acids 48: 2375-88
MeSH Terms: Animals, Arginase, Biogenic Polyamines, Helicobacter Infections, Helicobacter pylori, Immune Evasion, Macrophage Activation, Macrophages, Mice, Mice, Knockout, Nitric Oxide Synthase Type II, Stomach, Th1 Cells, Th17 Cells
Added April 22, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
Early Th1 immunity promotes immune tolerance and may impair graft-versus-leukemia effect after allogeneic hematopoietic cell transplantation.
Engelhardt BG, Paczesny S, Jung DK, Daguindau E, Jagasia M, Savani BN, Chinratanalab W, Cornell RF, Goodman S, Greer JP, Kassim AA, Sengsayadeth S, Yoder SM, Rock MT, Crowe JE
(2016) Haematologica 101: e204-8
MeSH Terms: Adult, Aged, Allografts, Female, Graft vs Leukemia Effect, Hematopoietic Stem Cell Transplantation, Humans, Immune Tolerance, Immunity, Cellular, Leukemia, Male, Middle Aged, Th1 Cells
Added February 4, 2016
0 Communities
2 Members
0 Resources
13 MeSH Terms
Mycobacterium tuberculosis TlyA Protein Negatively Regulates T Helper (Th) 1 and Th17 Differentiation and Promotes Tuberculosis Pathogenesis.
Rahman MA, Sobia P, Dwivedi VP, Bhawsar A, Singh DK, Sharma P, Moodley P, Van Kaer L, Bishai WR, Das G
(2015) J Biol Chem 290: 14407-17
MeSH Terms: Animals, Bacterial Proteins, Host-Pathogen Interactions, Interleukin-10, Interleukin-12, Lung, Macrophages, Mice, Inbred BALB C, Mice, Inbred C57BL, Mutation, Mycobacterium tuberculosis, Th1 Cells, Th17 Cells, Tuberculosis, Virulence Factors
Added September 28, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Regulation of the Th1 genomic locus from Ifng through Tmevpg1 by T-bet.
Collier SP, Henderson MA, Tossberg JT, Aune TM
(2014) J Immunol 193: 3959-65
MeSH Terms: Animals, Cell Lineage, Enhancer Elements, Genetic, Epigenesis, Genetic, Genetic Loci, Interferon-gamma, Mice, Mice, Inbred BALB C, Proto-Oncogene Protein c-ets-1, RNA, Long Noncoding, Regulatory Sequences, Nucleic Acid, T-Box Domain Proteins, Th1 Cells, Transcription Factor RelA
Added December 8, 2014
1 Communities
2 Members
0 Resources
14 MeSH Terms
Heme oxygenase-1 dysregulates macrophage polarization and the immune response to Helicobacter pylori.
Gobert AP, Verriere T, Asim M, Barry DP, Piazuelo MB, de Sablet T, Delgado AG, Bravo LE, Correa P, Peek RM, Chaturvedi R, Wilson KT
(2014) J Immunol 193: 3013-22
MeSH Terms: Animals, Antigens, Bacterial, Bacterial Proteins, Cell Line, Enzyme Inhibitors, Gastric Mucosa, Gastritis, Helicobacter Infections, Helicobacter pylori, Heme Oxygenase-1, Humans, Imidazoles, Inflammation, Interleukin-10, MAP Kinase Signaling System, Macrophages, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Knockout, NF-E2-Related Factor 2, Nitric Oxide Synthase Type II, Phagocytosis, Phosphorylation, Pyridines, Signal Transduction, Stomach, Th1 Cells, Th17 Cells, p38 Mitogen-Activated Protein Kinases
Added January 20, 2015
0 Communities
3 Members
0 Resources
30 MeSH Terms