Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 12

Publication Record

Connections

Bcl2-Expressing Quiescent Type B Neural Stem Cells in the Ventricular-Subventricular Zone Are Resistant to Concurrent Temozolomide/X-Irradiation.
Cameron BD, Traver G, Roland JT, Brockman AA, Dean D, Johnson L, Boyd K, Ihrie RA, Freeman ML
(2019) Stem Cells 37: 1629-1639
MeSH Terms: Animals, Antineoplastic Agents, Alkylating, Apoptosis, Chemoradiotherapy, DNA Breaks, Double-Stranded, DNA Repair, Disease Models, Animal, Drug Resistance, Female, Glioblastoma, Lateral Ventricles, Male, Mice, Mice, Inbred C57BL, Neural Stem Cells, Neurogenesis, Proto-Oncogene Proteins c-bcl-2, Temozolomide, X-Ray Therapy
Added March 3, 2020
0 Communities
2 Members
0 Resources
19 MeSH Terms
Effect of selumetinib vs chemotherapy on progression-free survival in uveal melanoma: a randomized clinical trial.
Carvajal RD, Sosman JA, Quevedo JF, Milhem MM, Joshua AM, Kudchadkar RR, Linette GP, Gajewski TF, Lutzky J, Lawson DH, Lao CD, Flynn PJ, Albertini MR, Sato T, Lewis K, Doyle A, Ancell K, Panageas KS, Bluth M, Hedvat C, Erinjeri J, Ambrosini G, Marr B, Abramson DH, Dickson MA, Wolchok JD, Chapman PB, Schwartz GK
(2014) JAMA 311: 2397-405
MeSH Terms: Adult, Aged, Aged, 80 and over, Antineoplastic Agents, Alkylating, Benzimidazoles, Dacarbazine, Disease Progression, Female, Humans, Male, Melanoma, Middle Aged, Survival Analysis, Temozolomide, Treatment Outcome, Uveal Neoplasms
Added June 27, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Phase II, open-label, randomized trial of the MEK1/2 inhibitor selumetinib as monotherapy versus temozolomide in patients with advanced melanoma.
Kirkwood JM, Bastholt L, Robert C, Sosman J, Larkin J, Hersey P, Middleton M, Cantarini M, Zazulina V, Kemsley K, Dummer R
(2012) Clin Cancer Res 18: 555-67
MeSH Terms: Adult, Aged, Aged, 80 and over, Antineoplastic Agents, Alkylating, Benzimidazoles, DNA Mutational Analysis, Dacarbazine, Disease-Free Survival, Drug Substitution, Female, Humans, Kaplan-Meier Estimate, MAP Kinase Kinase 1, MAP Kinase Kinase 2, Male, Melanoma, Middle Aged, Mutation, Neoplasm Staging, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins p21(ras), Temozolomide, Treatment Outcome, Young Adult
Added March 20, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
A phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets.
Su Y, Amiri KI, Horton LW, Yu Y, Ayers GD, Koehler E, Kelley MC, Puzanov I, Richmond A, Sosman JA
(2010) Clin Cancer Res 16: 348-57
MeSH Terms: Adult, Aged, Antineoplastic Combined Chemotherapy Protocols, Boronic Acids, Bortezomib, Chemokines, Dacarbazine, Drug Administration Schedule, Female, Humans, Male, Melanoma, Middle Aged, NF-kappa B, Proteasome Endopeptidase Complex, Proteasome Inhibitors, Pyrazines, Skin Neoplasms, Temozolomide, Treatment Outcome
Added June 14, 2013
2 Communities
5 Members
0 Resources
20 MeSH Terms
Phase 2 trial of combination thalidomide plus temozolomide in patients with metastatic malignant melanoma: Southwest Oncology Group S0508.
Clark JI, Moon J, Hutchins LF, Sosman JA, Kast WM, Da Silva DM, Liu PY, Thompson JA, Flaherty LE, Sondak VK
(2010) Cancer 116: 424-31
MeSH Terms: Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols, Dacarbazine, Female, Humans, Male, Melanoma, Middle Aged, Neoplasm Metastasis, Skin Neoplasms, Temozolomide, Thalidomide
Added March 20, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Molecular determinants of melanoma malignancy: selecting targets for improved efficacy of chemotherapy.
Yang J, Zaja-Milatovic S, Thu YM, Lee F, Smykla R, Richmond A
(2009) Mol Cancer Ther 8: 636-47
MeSH Terms: Animals, Antineoplastic Agents, Benzenesulfonates, Biomarkers, Tumor, Dacarbazine, Drug Delivery Systems, Drug Synergism, Female, Gene Expression Regulation, Neoplastic, Humans, Imidazoles, Melanoma, Mice, Mice, Inbred BALB C, Mice, Nude, Models, Biological, Niacinamide, Phenylurea Compounds, Pyridines, Quinoxalines, Skin Neoplasms, Sorafenib, Substrate Specificity, Temozolomide, Treatment Outcome, Tumor Cells, Cultured, Xenograft Model Antitumor Assays
Added June 14, 2013
2 Communities
2 Members
0 Resources
27 MeSH Terms
Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: a phase II Cytokine Working Group study.
Atkins MB, Sosman JA, Agarwala S, Logan T, Clark JI, Ernstoff MS, Lawson D, Dutcher JP, Weiss G, Curti B, Margolin KA
(2008) Cancer 113: 2139-45
MeSH Terms: Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols, Brain Neoplasms, Combined Modality Therapy, Cranial Irradiation, Dacarbazine, Female, Humans, Male, Melanoma, Middle Aged, Temozolomide, Thalidomide
Added March 20, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Temozolomide-associated organizing pneumonitis.
Maldonado F, Limper AH, Lim KG, Aubrey MC
(2007) Mayo Clin Proc 82: 771-3
MeSH Terms: Aged, 80 and over, Antineoplastic Agents, Alkylating, Dacarbazine, Glioblastoma, Humans, Male, Pneumocystis carinii, Pneumonia, Pneumocystis, Temozolomide
Added February 1, 2016
0 Communities
1 Members
0 Resources
9 MeSH Terms
Hypoxia-inducible factor-1 inhibition in combination with temozolomide treatment exhibits robust antitumor efficacy in vivo.
Li L, Lin X, Shoemaker AR, Albert DH, Fesik SW, Shen Y
(2006) Clin Cancer Res 12: 4747-54
MeSH Terms: Administration, Oral, Angiogenesis Inhibitors, Animals, Antineoplastic Agents, Aryl Hydrocarbon Receptor Nuclear Translocator, Caspases, Cell Death, Cell Line, Tumor, Cell Proliferation, Dacarbazine, Disease Models, Animal, Dose-Response Relationship, Drug, Glucose, Humans, Hypoxia, Indazoles, Mice, Mice, SCID, Phenylurea Compounds, Structure-Activity Relationship, Temozolomide, Transplantation, Heterologous, Xenograft Model Antitumor Assays
Added March 5, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Augmenting chemosensitivity of malignant melanoma tumors via proteasome inhibition: implication for bortezomib (VELCADE, PS-341) as a therapeutic agent for malignant melanoma.
Amiri KI, Horton LW, LaFleur BJ, Sosman JA, Richmond A
(2004) Cancer Res 64: 4912-8
MeSH Terms: Active Transport, Cell Nucleus, Animals, Antineoplastic Agents, Antineoplastic Combined Chemotherapy Protocols, Apoptosis, Boronic Acids, Bortezomib, Cell Division, Cell Line, Tumor, Dacarbazine, Drug Synergism, Female, Gene Expression, Humans, Melanoma, Mice, Mice, Inbred BALB C, NF-kappa B, Neovascularization, Pathologic, Protease Inhibitors, Pyrazines, Temozolomide
Added June 14, 2013
2 Communities
3 Members
0 Resources
22 MeSH Terms