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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 78

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RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT.
Kryshtal DO, Blackwell DJ, Egly CL, Smith AN, Batiste SM, Johnston JN, Laver DR, Knollmann BC
(2021) Circ Res 128: 321-331
MeSH Terms: Action Potentials, Animals, Anti-Arrhythmia Agents, Calcium Channel Blockers, Calcium Signaling, Calsequestrin, Disease Models, Animal, Female, Flecainide, HEK293 Cells, Heart Rate, Humans, Male, Mice, Knockout, Myocytes, Cardiac, Phosphorylation, Ryanodine Receptor Calcium Release Channel, Sarcoplasmic Reticulum, Sheep, Domestic, Tachycardia, Ventricular, Voltage-Gated Sodium Channel Blockers
Added December 21, 2020
1 Communities
0 Members
0 Resources
21 MeSH Terms
Calmodulin Mutations Associated with Heart Arrhythmia: A Status Report.
Chazin WJ, Johnson CN
(2020) Int J Mol Sci 21:
MeSH Terms: Arrhythmias, Cardiac, Calcium Signaling, Calmodulin, Humans, Ion Channels, Long QT Syndrome, Myocytes, Cardiac, Ryanodine Receptor Calcium Release Channel, Tachycardia, Ventricular
Added March 11, 2020
0 Communities
1 Members
0 Resources
9 MeSH Terms
Atropine-induced sinus tachycardia protects against exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia.
Kannankeril PJ, Shoemaker MB, Gayle KA, Fountain D, Roden DM, Knollmann BC
(2020) Europace 22: 643-648
MeSH Terms: Animals, Atropine, Humans, Mice, Prospective Studies, Ryanodine Receptor Calcium Release Channel, Tachycardia, Sinus, Tachycardia, Ventricular
Added March 24, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
Heart failure and atrial tachyarrhythmia on abiraterone: A pharmacovigilance study.
Bretagne M, Lebrun-Vignes B, Pariente A, Shaffer CM, Malouf GG, Dureau P, Potey C, Funck-Brentano C, Roden DM, Moslehi JJ, Salem JE
(2020) Arch Cardiovasc Dis 113: 9-21
MeSH Terms: Adverse Drug Reaction Reporting Systems, Aged, Aged, 80 and over, Androgen Antagonists, Androstenes, Antineoplastic Agents, Hormonal, Cardiotoxicity, Databases, Factual, Heart Failure, Humans, Male, Middle Aged, Pharmacovigilance, Phenylthiohydantoin, Prostatic Neoplasms, Retrospective Studies, Risk Assessment, Risk Factors, Tachycardia, Supraventricular, Time Factors
Added November 12, 2019
0 Communities
2 Members
0 Resources
20 MeSH Terms
Calmodulin Mutants Linked to Catecholaminergic Polymorphic Ventricular Tachycardia Fail to Inhibit Human RyR2 Channels.
Walweel K, Gomez-Hurtado N, Oo YW, Beard NA, Dos Remedios C, Johnson CN, Chazin WJ, van Helden DF, Knollmann BC, Laver DR
(2017) J Am Coll Cardiol 70: 115-117
MeSH Terms: Calmodulin, Heart Ventricles, Humans, In Vitro Techniques, Mutation, Phosphorylation, Ryanodine Receptor Calcium Release Channel, Tachycardia, Ventricular
Added March 24, 2018
0 Communities
1 Members
0 Resources
8 MeSH Terms
Efficacy of Flecainide in the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia: A Randomized Clinical Trial.
Kannankeril PJ, Moore JP, Cerrone M, Priori SG, Kertesz NJ, Ro PS, Batra AS, Kaufman ES, Fairbrother DL, Saarel EV, Etheridge SP, Kanter RJ, Carboni MP, Dzurik MV, Fountain D, Chen H, Ely EW, Roden DM, Knollmann BC
(2017) JAMA Cardiol 2: 759-766
MeSH Terms: Adolescent, Adrenergic beta-Antagonists, Anti-Arrhythmia Agents, Cross-Over Studies, Death, Sudden, Cardiac, Defibrillators, Implantable, Drug Therapy, Combination, Exercise, Exercise Test, Female, Flecainide, Humans, Male, Maximum Tolerated Dose, Single-Blind Method, Tachycardia, Ventricular, Young Adult
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Novel CPVT-Associated Calmodulin Mutation in CALM3 (CALM3-A103V) Activates Arrhythmogenic Ca Waves and Sparks.
Gomez-Hurtado N, Boczek NJ, Kryshtal DO, Johnson CN, Sun J, Nitu FR, Cornea RL, Chazin WJ, Calvert ML, Tester DJ, Ackerman MJ, Knollmann BC
(2016) Circ Arrhythm Electrophysiol 9:
MeSH Terms: Action Potentials, Adult, Animals, Calmodulin, DNA Mutational Analysis, Electrocardiography, Exercise Test, Female, Genotype, Humans, Long QT Syndrome, Male, Mice, Phenotype, Ryanodine, Tachycardia, Ventricular
Added April 18, 2017
0 Communities
1 Members
0 Resources
16 MeSH Terms
Overactive bladder and autonomic dysfunction: Lower urinary tract symptoms in females with postural tachycardia syndrome.
Kaufman MR, Chang-Kit L, Raj SR, Black BK, Milam DF, Reynolds WS, Biaggioni I, Robertson D, Dmochowski RR
(2017) Neurourol Urodyn 36: 610-613
MeSH Terms: Adult, Female, Humans, Lower Urinary Tract Symptoms, Pilot Projects, Postural Orthostatic Tachycardia Syndrome, Quality of Life, Surveys and Questionnaires, Urinary Bladder, Overactive
Added September 16, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Association between perioperative dexmedetomidine and arrhythmias after surgery for congenital heart disease.
Shuplock JM, Smith AH, Owen J, Van Driest SL, Marshall M, Saville B, Xu M, Radbill AE, Fish FA, Kannankeril PJ
(2015) Circ Arrhythm Electrophysiol 8: 643-50
MeSH Terms: Adrenergic alpha-2 Receptor Agonists, Arrhythmias, Cardiac, Bradycardia, Cardiac Surgical Procedures, Chi-Square Distribution, Child, Child, Preschool, Dexmedetomidine, Female, Heart Defects, Congenital, Humans, Incidence, Infant, Infant, Newborn, Logistic Models, Male, Multivariate Analysis, Odds Ratio, Propensity Score, Retrospective Studies, Risk Factors, Tachycardia, Tennessee, Time Factors, Treatment Outcome
Added April 11, 2017
0 Communities
1 Members
0 Resources
25 MeSH Terms
Common genetic variants and response to atrial fibrillation ablation.
Shoemaker MB, Bollmann A, Lubitz SA, Ueberham L, Saini H, Montgomery J, Edwards T, Yoneda Z, Sinner MF, Arya A, Sommer P, Delaney J, Goyal SK, Saavedra P, Kanagasundram A, Whalen SP, Roden DM, Hindricks G, Ellis CR, Ellinor PT, Darbar D, Husser D
(2015) Circ Arrhythm Electrophysiol 8: 296-302
MeSH Terms: Aged, Atrial Fibrillation, Atrial Flutter, Boston, Catheter Ablation, Chi-Square Distribution, Chromosomes, Human, Pair 1, Chromosomes, Human, Pair 16, Chromosomes, Human, Pair 4, Female, Gene Frequency, Genetic Association Studies, Genetic Predisposition to Disease, Germany, Humans, Male, Middle Aged, Multivariate Analysis, Odds Ratio, Phenotype, Polymorphism, Single Nucleotide, Proportional Hazards Models, Recurrence, Risk Factors, Tachycardia, Supraventricular, Tennessee, Time Factors, Treatment Outcome
Added February 22, 2016
0 Communities
3 Members
0 Resources
28 MeSH Terms