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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 8 of 8

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TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis.
Fang J, Muto T, Kleppe M, Bolanos LC, Hueneman KM, Walker CS, Sampson L, Wellendorf AM, Chetal K, Choi K, Salomonis N, Choi Y, Zheng Y, Cancelas JA, Levine RL, Starczynowski DT
(2018) Cell Rep 22: 1250-1262
MeSH Terms: Animals, Enzyme Activation, Hematopoiesis, Hematopoietic Stem Cells, Homeostasis, I-kappa B Kinase, Mice, Mice, Transgenic, NF-kappa B, Signal Transduction, TNF Receptor-Associated Factor 6
Added February 26, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms
SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer.
Lu W, Liu S, Li B, Xie Y, Izban MG, Ballard BR, Sathyanarayana SA, Adunyah SE, Matusik RJ, Chen Z
(2017) Oncogene 36: 1364-1373
MeSH Terms: Animals, Cell Line, Tumor, Disease Models, Animal, Enhancer of Zeste Homolog 2 Protein, Gene Knockout Techniques, Histones, Humans, Lysine, Male, Mice, PTEN Phosphohydrolase, Prostate, Prostatic Neoplasms, Protein Stability, S-Phase Kinase-Associated Proteins, TNF Receptor-Associated Factor 6, Tumor Suppressor Protein p53, Ubiquitination
Added April 18, 2017
0 Communities
1 Members
0 Resources
18 MeSH Terms
Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt.
Yazlovitskaya EM, Tseng HY, Viquez O, Tu T, Mernaugh G, McKee KK, Riggins K, Quaranta V, Pathak A, Carter BD, Yurchenco P, Sonnenberg A, Böttcher RT, Pozzi A, Zent R
(2015) Mol Biol Cell 26: 1857-74
MeSH Terms: Animals, Integrin alpha3beta1, Kidney Tubules, Collecting, Mice, Mice, Knockout, Morphogenesis, Proto-Oncogene Proteins c-akt, Signal Transduction, TNF Receptor-Associated Factor 6, Ubiquitination
Added February 4, 2016
1 Communities
4 Members
0 Resources
10 MeSH Terms
Helicobacter pylori CagA activates NF-kappaB by targeting TAK1 for TRAF6-mediated Lys 63 ubiquitination.
Lamb A, Yang XD, Tsang YH, Li JD, Higashi H, Hatakeyama M, Peek RM, Blanke SR, Chen LF
(2009) EMBO Rep 10: 1242-9
MeSH Terms: Animals, Antigens, Bacterial, Bacterial Proteins, Cell Line, Cytokines, Gene Expression Regulation, Humans, Inflammation, Lysine, MAP Kinase Kinase Kinases, Mice, NF-kappa B, TNF Receptor-Associated Factor 6, Ubiquitin
Added March 5, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor.
Vilar M, Charalampopoulos I, Kenchappa RS, Reversi A, Klos-Applequist JM, Karaca E, Simi A, Spuch C, Choi S, Friedman WJ, Ericson J, Schiavo G, Carter BD, Ibáñez CF
(2009) J Cell Sci 122: 3351-7
MeSH Terms: Amino Acid Sequence, Animals, Axons, COS Cells, Caspase 3, Cell Death, Chlorocebus aethiops, Cross-Linking Reagents, Disulfides, Humans, Intracellular Signaling Peptides and Proteins, JNK Mitogen-Activated Protein Kinases, Ligands, Molecular Sequence Data, Mutant Proteins, NF-kappa B, Nerve Growth Factors, Protein Multimerization, Protein Transport, Rats, Receptor, Nerve Growth Factor, Receptor-Interacting Protein Serine-Threonine Kinase 2, Signal Transduction, TNF Receptor-Associated Factor 6
Added March 5, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor.
Geetha T, Kenchappa RS, Wooten MW, Carter BD
(2005) EMBO J 24: 3859-68
MeSH Terms: Active Transport, Cell Nucleus, Animals, Apoptosis, Brain, Cell Line, DNA-Binding Proteins, Humans, Intracellular Signaling Peptides and Proteins, Ligands, Lysine, Mice, Mice, Knockout, Neurons, Polyubiquitin, Protein Binding, Receptor, Nerve Growth Factor, TNF Receptor-Associated Factor 6, Transcription Factor TFIIH, Transcription Factors
Added March 5, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Neurotrophin signaling through the p75 receptor is deficient in traf6-/- mice.
Yeiser EC, Rutkoski NJ, Naito A, Inoue J, Carter BD
(2004) J Neurosci 24: 10521-9
MeSH Terms: Animals, Animals, Newborn, Apoptosis, Brain-Derived Neurotrophic Factor, Cells, Cultured, Genes, Reporter, JNK Mitogen-Activated Protein Kinases, Mice, Mice, Knockout, NF-kappa B, Nerve Growth Factor, Nerve Growth Factors, Receptor, Nerve Growth Factor, Schwann Cells, Signal Transduction, Superior Cervical Ganglion, TNF Receptor-Associated Factor 6
Added March 5, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
A functional interaction between the p75 neurotrophin receptor interacting factors, TRAF6 and NRIF.
Gentry JJ, Rutkoski NJ, Burke TL, Carter BD
(2004) J Biol Chem 279: 16646-56
MeSH Terms: Animals, Carrier Proteins, Cell Line, DNA-Binding Proteins, Humans, Intracellular Signaling Peptides and Proteins, Protein Binding, Protein Transport, Proteins, Receptor, Nerve Growth Factor, Receptors, Nerve Growth Factor, Signal Transduction, TNF Receptor-Associated Factor 6
Added March 5, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms