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Results: 1 to 10 of 16

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The TAL1/SCL transcription factor regulates cell cycle progression and proliferation in differentiating murine bone marrow monocyte precursors.
Dey S, Curtis DJ, Jane SM, Brandt SJ
(2010) Mol Cell Biol 30: 2181-92
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Cycle, Cell Differentiation, Cell Line, Cell Proliferation, Cell Survival, Cyclin-Dependent Kinase Inhibitor p16, DNA, GATA2 Transcription Factor, Gene Expression Regulation, Gene Knockout Techniques, Introns, Leukopoiesis, Mice, Mice, Knockout, Monocytes, Protein Binding, Proto-Oncogene Proteins, RNA, Messenger, Stem Cells, T-Cell Acute Lymphocytic Leukemia Protein 1, beta-Galactosidase
Added March 5, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors.
Cai Y, Xu Z, Xie J, Ham AJ, Koury MJ, Hiebert SW, Brandt SJ
(2009) Biochem Biophys Res Commun 390: 295-301
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Line, Tumor, Erythroid Precursor Cells, Mice, Nuclear Proteins, Proto-Oncogene Proteins, Repressor Proteins, T-Cell Acute Lymphocytic Leukemia Protein 1, Transcription Factors
Added March 5, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Expression of the TAL1/SCL transcription factor in physiological and pathological vascular processes.
Tang T, Shi Y, Opalenik SR, Brantley-Sieders DM, Chen J, Davidson JM, Brandt SJ
(2006) J Pathol 210: 121-9
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Line, Tumor, Endothelial Cells, Endothelium, Vascular, Female, Gonadotropins, Hematopoietic Stem Cells, Immunohistochemistry, Islets of Langerhans, Lymphangiogenesis, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Transgenic, Microcirculation, Models, Animal, Neovascularization, Pathologic, Neovascularization, Physiologic, Ovary, Ovulation, Proto-Oncogene Proteins, T-Cell Acute Lymphocytic Leukemia Protein 1, Uterus, Vascular Endothelial Growth Factor Receptor-2, Wound Healing
Added December 10, 2013
0 Communities
2 Members
0 Resources
26 MeSH Terms
Transcriptional link between blood and bone: the stem cell leukemia gene and its +19 stem cell enhancer are active in bone cells.
Pimanda JE, Silberstein L, Dominici M, Dekel B, Bowen M, Oldham S, Kallianpur A, Brandt SJ, Tannahill D, Gƶttgens B, Green AR
(2006) Mol Cell Biol 26: 2615-25
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Blood, Bone and Bones, Cell Differentiation, Cells, Cultured, DNA-Binding Proteins, Enhancer Elements, Genetic, GATA2 Transcription Factor, Gene Expression Regulation, Developmental, Genes, Reporter, Mice, Mice, Transgenic, Muscle, Smooth, Vascular, Nuclear Proteins, Osteogenesis, Proto-Oncogene Protein c-fli-1, Proto-Oncogene Proteins, Skeleton, Stem Cells, T-Cell Acute Lymphocytic Leukemia Protein 1, Transcription Factors, Transcription, Genetic
Added March 5, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Tal1/SCL binding to pericentromeric DNA represses transcription.
Wen J, Huang S, Pack SD, Yu X, Brandt SJ, Noguchi CT
(2005) J Biol Chem 280: 12956-66
MeSH Terms: Amino Acid Motifs, Base Sequence, Basic Helix-Loop-Helix Transcription Factors, Binding Sites, Cell Nucleus, Chromatin, Chromatin Immunoprecipitation, Chromosomes, DNA, DNA Methylation, DNA Primers, DNA-Binding Proteins, Genes, Reporter, HeLa Cells, Heterochromatin, Histones, Humans, Hydroxamic Acids, Image Processing, Computer-Assisted, In Situ Hybridization, Fluorescence, K562 Cells, Leukocytes, Male, Models, Genetic, Molecular Sequence Data, Plasmids, Protein Binding, Proto-Oncogene Proteins, Reverse Transcriptase Polymerase Chain Reaction, Sequence Homology, Nucleic Acid, T-Cell Acute Lymphocytic Leukemia Protein 1, Transcription Factors, Transcription, Genetic
Added March 5, 2014
0 Communities
1 Members
0 Resources
33 MeSH Terms
Identification of a TAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 in erythroid gene expression and differentiation.
Xu Z, Huang S, Chang LS, Agulnick AD, Brandt SJ
(2003) Mol Cell Biol 23: 7585-99
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Blood Proteins, Cell Differentiation, Cytoskeletal Proteins, DNA-Binding Proteins, Erythrocytes, Erythroid-Specific DNA-Binding Factors, GATA1 Transcription Factor, Gene Expression Regulation, Genes, Regulator, Helix-Loop-Helix Motifs, LIM Domain Proteins, Leukemia, Erythroblastic, Acute, Membrane Proteins, Mice, Promoter Regions, Genetic, Proto-Oncogene Proteins, T-Cell Acute Lymphocytic Leukemia Protein 1, Transcription Factors, Transcription, Genetic, Tumor Cells, Cultured
Added March 5, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development.
Takahashi T, Takahashi K, St John PL, Fleming PA, Tomemori T, Watanabe T, Abrahamson DR, Drake CJ, Shirasawa T, Daniel TO
(2003) Mol Cell Biol 23: 1817-31
MeSH Terms: Alleles, Animals, Basic Helix-Loop-Helix Transcription Factors, Blotting, Northern, Blotting, Western, Catalysis, Catalytic Domain, Cell Division, Cytoplasm, DNA-Binding Proteins, Endothelium, Vascular, Ephrin-B2, Green Fluorescent Proteins, Homozygote, Kidney, Luminescent Proteins, Mice, Microscopy, Electron, Models, Genetic, Mutation, Myocardium, Platelet Endothelial Cell Adhesion Molecule-1, Precipitin Tests, Protein Tyrosine Phosphatases, Proto-Oncogene Proteins, Receptor Protein-Tyrosine Kinases, Receptor, TIE-2, Receptor-Like Protein Tyrosine Phosphatases, Class 3, Recombinant Fusion Proteins, Recombination, Genetic, Reverse Transcriptase Polymerase Chain Reaction, T-Cell Acute Lymphocytic Leukemia Protein 1, Time Factors, Transcription Factors, Tyrosine, Vascular Endothelial Growth Factor Receptor-2
Added August 27, 2013
1 Communities
1 Members
0 Resources
36 MeSH Terms
Phosphorylation by mitogen-activated protein kinase mediates the hypoxia-induced turnover of the TAL1/SCL transcription factor in endothelial cells.
Tang T, Arbiser JL, Brandt SJ
(2002) J Biol Chem 277: 18365-72
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Catalysis, Cell Hypoxia, Cell Line, Cell Line, Transformed, Cysteine Endopeptidases, DNA-Binding Proteins, Endothelium, Vascular, Humans, Hydrolysis, Mice, Mitogen-Activated Protein Kinases, Multienzyme Complexes, Phosphorylation, Proteasome Endopeptidase Complex, Proto-Oncogene Proteins, Serine, T-Cell Acute Lymphocytic Leukemia Protein 1, Transcription Factors
Added March 5, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL.
Huang S, Qiu Y, Shi Y, Xu Z, Brandt SJ
(2000) EMBO J 19: 6792-803
MeSH Terms: Acetylation, Acetyltransferases, Animals, Basic Helix-Loop-Helix Transcription Factors, Binding Sites, Cell Cycle Proteins, Cell Differentiation, Conserved Sequence, DNA-Binding Proteins, HeLa Cells, Helix-Loop-Helix Motifs, Histone Acetyltransferases, Humans, Leukemia, Erythroblastic, Acute, Lysine, Mice, Protein Biosynthesis, Proto-Oncogene Proteins, Recombinant Proteins, T-Cell Acute Lymphocytic Leukemia Protein 1, Transcription Factors, Transfection, Tumor Cells, Cultured, p300-CBP Transcription Factors
Added March 5, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor.
Huang S, Brandt SJ
(2000) Mol Cell Biol 20: 2248-59
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Differentiation, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Humans, Leukemia, Erythroblastic, Acute, Mice, Proto-Oncogene Proteins, Repressor Proteins, Signal Transduction, Sin3 Histone Deacetylase and Corepressor Complex, T-Cell Acute Lymphocytic Leukemia Protein 1, Transcription Factors, Tumor Cells, Cultured
Added March 5, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms