Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 7 of 7

Publication Record

Connections

An orthogonal methods assessment of topical drug concentrations in skin and the impact for risk assessment in the viable epidermis.
Hollingshead BD, Tomlinson L, Finley J, Doshna C, Ritenour C, Barricklow J, Oppenheimer SR, O'Neil SP, Moore JL, Patterson NH, Nicholson SP, Norris JL, Caprioli RM, Beaumont K, King-Ahmad AJ, Vispute S, Cook JC, Radi Z, Schuler M
(2021) Regul Toxicol Pharmacol 123: 104934
MeSH Terms: Animals, Epidermis, Humans, Mass Spectrometry, Pharmaceutical Preparations, Risk Assessment, Skin, Skin Absorption, Swine, Swine, Miniature
Added November 20, 2021
0 Communities
1 Members
0 Resources
10 MeSH Terms
Localized low-dose rhBMP-2 is effective at promoting bone regeneration in mandibular segmental defects.
Carlisle P, Guda T, Silliman DT, Burdette AJ, Talley AD, Alvarez R, Tucker D, Hale RG, Guelcher SA, BrownBaer PR
(2019) J Biomed Mater Res B Appl Biomater 107: 1491-1503
MeSH Terms: Animals, Bone Morphogenetic Protein 2, Bone Regeneration, Calcium Phosphates, Drug Delivery Systems, Durapatite, Humans, Mandible, Mandibular Injuries, Recombinant Proteins, Swine, Swine, Miniature, Tomography, X-Ray Computed
Added March 20, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In Vivo.
Blobaum AL, Byers FW, Bridges TM, Locuson CW, Conn PJ, Lindsley CW, Daniels JS
(2015) Drug Metab Dispos 43: 1718-26
MeSH Terms: Androgen Receptor Antagonists, Animals, Cytochrome P-450 CYP3A, Drug Evaluation, Preclinical, Enzyme Activators, Female, Flutamide, Guinea Pigs, Humans, Male, Mice, Microsomes, Liver, Rats, Rats, Sprague-Dawley, Swine, Swine, Miniature
Added February 18, 2016
0 Communities
1 Members
0 Resources
16 MeSH Terms
Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs.
Vaclavikova R, Soucek P, Svobodova L, Anzenbacher P, Simek P, Guengerich FP, Gut I
(2004) Drug Metab Dispos 32: 666-74
MeSH Terms: Adolescent, Adult, Animals, Antineoplastic Agents, Phytogenic, Cytochrome P-450 Enzyme System, Docetaxel, Enzyme Inhibitors, Flavonoids, Flavonols, Humans, In Vitro Techniques, Isoenzymes, Kinetics, Male, Microsomes, Liver, Paclitaxel, Rats, Rats, Wistar, Species Specificity, Swine, Swine, Miniature, Taxoids, Troleandomycin
Added May 26, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Simplified laparoscopic radical cystectomy with orthotopic ileal neobladder creation in a porcine model.
Baldwin DD, Herrell SD, Dunbar JA, Jung C, Nunnally AH, Roberts RL, Leach JR, Parekh DJ, McDougall EM
(2003) J Endourol 17: 307-12
MeSH Terms: Anastomosis, Surgical, Animals, Cystectomy, Disease Models, Animal, Female, Ileum, Laparoscopy, Minimally Invasive Surgical Procedures, Recovery of Function, Swine, Miniature, Treatment Outcome, Urinary Reservoirs, Continent, Urodynamics
Added March 15, 2017
0 Communities
1 Members
0 Resources
13 MeSH Terms
Pig and minipig cytochromes P450.
Anzenbacher P, Anzerbacherová E, Zuber R, Soucek P, Guengerich F
(2002) Drug Metab Dispos 30: 100-2
MeSH Terms: Animals, Cytochrome P-450 Enzyme System, Enzyme Induction, Isoenzymes, Microsomes, Liver, Swine, Swine, Miniature
Added May 26, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs.
Soucek P, Zuber R, Anzenbacherová E, Anzenbacher P, Guengerich FP
(2001) BMC Pharmacol 1: 11
MeSH Terms: Animals, Aryl Hydrocarbon Hydroxylases, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System, Humans, Microsomes, Liver, Sequence Analysis, Protein, Species Specificity, Steroid Hydroxylases, Substrate Specificity, Swine, Miniature
Added May 26, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms