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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 302

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An orthogonal methods assessment of topical drug concentrations in skin and the impact for risk assessment in the viable epidermis.
Hollingshead BD, Tomlinson L, Finley J, Doshna C, Ritenour C, Barricklow J, Oppenheimer SR, O'Neil SP, Moore JL, Patterson NH, Nicholson SP, Norris JL, Caprioli RM, Beaumont K, King-Ahmad AJ, Vispute S, Cook JC, Radi Z, Schuler M
(2021) Regul Toxicol Pharmacol 123: 104934
MeSH Terms: Animals, Epidermis, Humans, Mass Spectrometry, Pharmaceutical Preparations, Risk Assessment, Skin, Skin Absorption, Swine, Swine, Miniature
Added November 20, 2021
0 Communities
1 Members
0 Resources
10 MeSH Terms
Heart slice culture system reliably demonstrates clinical drug-related cardiotoxicity.
Miller JM, Meki MH, Ou Q, George SA, Gams A, Abouleisa RRE, Tang XL, Ahern BM, Giridharan GA, El-Baz A, Hill BG, Satin J, Conklin DJ, Moslehi J, Bolli R, Ribeiro AJS, Efimov IR, Mohamed TMA
(2020) Toxicol Appl Pharmacol 406: 115213
MeSH Terms: Adult, Aged, Animals, Antineoplastic Agents, Apoptosis, Cardiotoxicity, Cardiotoxins, Doxorubicin, Female, Heart, Humans, Induced Pluripotent Stem Cells, Male, Middle Aged, Models, Biological, Swine, Tissue Culture Techniques, Trastuzumab
Added September 29, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
Delineating the Molecular Basis of the Calmodulin‒bMunc13-2 Interaction by Cross-Linking/Mass Spectrometry-Evidence for a Novel CaM Binding Motif in bMunc13-2.
Piotrowski C, Moretti R, Ihling CH, Haedicke A, Liepold T, Lipstein N, Meiler J, Jahn O, Sinz A
(2020) Cells 9:
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Animals, Binding Sites, Calmodulin, Cattle, Cross-Linking Reagents, Hydrophobic and Hydrophilic Interactions, Mass Spectrometry, Models, Molecular, Nerve Tissue Proteins, Protein Binding, Protein Domains, Rats, Swine
Added March 21, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Tolerance of porcine pancreatic enzymes despite positive skin testing in alpha-gal allergy.
Stone CA, Choudhary S, Patterson MF, Rukasin CRF, Coleman DT, Phillips EJ, Commins SP
(2020) J Allergy Clin Immunol Pract 8: 1728-1732.e1
MeSH Terms: Animals, Disaccharides, Food Hypersensitivity, Humans, Immunoglobulin E, Swine
Added March 30, 2020
0 Communities
1 Members
0 Resources
6 MeSH Terms
Normal Saline solutions cause endothelial dysfunction through loss of membrane integrity, ATP release, and inflammatory responses mediated by P2X7R/p38 MAPK/MK2 signaling pathways.
Cheung-Flynn J, Alvis BD, Hocking KM, Guth CM, Luo W, McCallister R, Chadalavada K, Polcz M, Komalavilas P, Brophy CM
(2019) PLoS One 14: e0220893
MeSH Terms: Adenosine Triphosphate, Animals, Aorta, Cell Membrane, Endothelial Cells, Humans, Inflammation, Intracellular Signaling Peptides and Proteins, Phosphorylation, Protein Serine-Threonine Kinases, Rats, Receptors, Purinergic P2X7, Saline Solution, Saphenous Vein, Signal Transduction, Swine, p38 Mitogen-Activated Protein Kinases
Added March 3, 2020
0 Communities
1 Members
0 Resources
17 MeSH Terms
Cyclin G1 and TASCC regulate kidney epithelial cell G-M arrest and fibrotic maladaptive repair.
Canaud G, Brooks CR, Kishi S, Taguchi K, Nishimura K, Magassa S, Scott A, Hsiao LL, Ichimura T, Terzi F, Yang L, Bonventre JV
(2019) Sci Transl Med 11:
MeSH Terms: Animals, Autophagy, Cell Compartmentation, Cell Cycle Checkpoints, Cell Dedifferentiation, Cyclin G1, Disease Models, Animal, Disease Progression, Epithelial Cells, Fibrosis, Humans, Kidney, Kidney Tubules, Proximal, LLC-PK1 Cells, Male, Mice, Renal Insufficiency, Chronic, Swine, TOR Serine-Threonine Kinases, Wound Healing
Added March 14, 2019
0 Communities
1 Members
0 Resources
20 MeSH Terms
Localized low-dose rhBMP-2 is effective at promoting bone regeneration in mandibular segmental defects.
Carlisle P, Guda T, Silliman DT, Burdette AJ, Talley AD, Alvarez R, Tucker D, Hale RG, Guelcher SA, BrownBaer PR
(2019) J Biomed Mater Res B Appl Biomater 107: 1491-1503
MeSH Terms: Animals, Bone Morphogenetic Protein 2, Bone Regeneration, Calcium Phosphates, Drug Delivery Systems, Durapatite, Humans, Mandible, Mandibular Injuries, Recombinant Proteins, Swine, Swine, Miniature, Tomography, X-Ray Computed
Added March 20, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension.
Hemnes AR, Rathinasabapathy A, Austin EA, Brittain EL, Carrier EJ, Chen X, Fessel JP, Fike CD, Fong P, Fortune N, Gerszten RE, Johnson JA, Kaplowitz M, Newman JH, Piana R, Pugh ME, Rice TW, Robbins IM, Wheeler L, Yu C, Loyd JE, West J
(2018) Eur Respir J 51:
MeSH Terms: Adult, Aged, Angiotensin-Converting Enzyme 2, Animals, Biomarkers, Cytokines, Female, Gene Expression, Humans, Hypertension, Pulmonary, Male, Middle Aged, Peptidyl-Dipeptidase A, Pilot Projects, Proof of Concept Study, Proto-Oncogene Mas, Proto-Oncogene Proteins, Pulmonary Artery, Receptors, G-Protein-Coupled, Superoxide Dismutase, Swine, Vascular Resistance
Added March 26, 2019
0 Communities
3 Members
0 Resources
22 MeSH Terms
Selective Activation of N,N'-Diacyl Rhodamine Pro-fluorophores Paired with Releasing Enzyme, Porcine Liver Esterase (PLE).
Abney KK, Ramos-Hunter SJ, Romaine IM, Goodwin JS, Sulikowski GA, Weaver CD
(2018) Chemistry 24: 8985-8988
MeSH Terms: Animals, Esterases, HEK293 Cells, Humans, Liver, Microscopy, Confocal, Rhodamines, Spectrometry, Fluorescence, Swine
Added April 10, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Limiting Injury During Saphenous Vein Graft Preparation For Coronary Arterial Bypass Prevents Metabolic Decompensation.
Cheung-Flynn J, Song J, Voskresensky I, Wise ES, Liu Y, Xiong Y, Eagle SS, Brophy CM, Flynn CR
(2017) Sci Rep 7: 14179
MeSH Terms: Animals, Coronary Artery Bypass, Energy Metabolism, Homeostasis, Humans, Hydrolysis, Metabolomics, Oxidation-Reduction, Oxidative Stress, Phospholipids, Pressure, Saphenous Vein, Swine, Vascular Grafting
Added May 14, 2018
0 Communities
2 Members
0 Resources
14 MeSH Terms