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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 7 of 7

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The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10.
Paulson CN, John K, Baxley RM, Kurniawan F, Orellana K, Francis R, Sobeck A, Eichman BF, Chazin WJ, Aihara H, Georg GI, Hawkinson JE, Bielinsky AK
(2019) Open Biol 9: 190117
MeSH Terms: Animals, Cell Survival, DNA Replication, DNA-Binding Proteins, Drug Discovery, Enzyme Inhibitors, Gene Expression, High-Throughput Nucleotide Sequencing, Humans, Kinetics, Minichromosome Maintenance Proteins, Molecular Structure, Protein Binding, Suramin, Xenopus
Added August 26, 2019
0 Communities
2 Members
0 Resources
15 MeSH Terms
The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells.
Wilson S, Greer B, Hooper J, Zijlstra A, Walker B, Quigley J, Hawthorne S
(2005) Biochem J 388: 967-72
MeSH Terms: Boron Compounds, Calcium, Catalysis, Cell Line, Tumor, Humans, Male, Prostatic Neoplasms, RNA, Messenger, Receptor, PAR-2, Recombinant Proteins, Serine Endopeptidases, Serine Proteinase Inhibitors, Signal Transduction, Substrate Specificity, Suramin
Added December 30, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms
Recent advances in drug-induced neuropathies.
Peltier AC, Russell JW
(2002) Curr Opin Neurol 15: 633-8
MeSH Terms: Animals, Antineoplastic Agents, Cisplatin, Humans, Immunosuppressive Agents, Paclitaxel, Peripheral Nervous System Diseases, Reverse Transcriptase Inhibitors, Suramin, Vincristine
Added December 10, 2013
0 Communities
1 Members
0 Resources
10 MeSH Terms
Suramin inhibition of growth factor receptor binding and mitogenicity in AKR-2B cells.
Coffey RJ, Leof EB, Shipley GD, Moses HL
(1987) J Cell Physiol 132: 143-8
MeSH Terms: Agar, Animals, Blood, Cell Line, Cells, Cultured, DNA Replication, Dose-Response Relationship, Drug, Epidermal Growth Factor, Fibroblast Growth Factor 2, Growth Substances, Heparin, Male, Mice, Mitosis, Peptides, Receptors, Somatotropin, Suramin, Transforming Growth Factors
Added March 28, 2014
1 Communities
1 Members
0 Resources
18 MeSH Terms
Inhibition of prostatic tumor cell proliferation by suramin: alterations in TGF alpha-mediated autocrine growth regulation and cell cycle distribution.
Kim JH, Sherwood ER, Sutkowski DM, Lee C, Kozlowski JM
(1991) J Urol 146: 171-6
MeSH Terms: Antineoplastic Agents, Cell Cycle, Cell Division, Cell Line, Depression, Chemical, Dose-Response Relationship, Drug, Drug Screening Assays, Antitumor, ErbB Receptors, Humans, Male, Prostatic Neoplasms, Suramin, Transforming Growth Factor alpha, Tumor Cells, Cultured
Added October 18, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Inhibitory effects of suramin on a human renal cell carcinoma line, causing nephrogenic hepatic dysfunction.
Chang SY, Yu DS, Sherwood ER, Kozlowski JM, Lee C
(1992) J Urol 147: 1147-50
MeSH Terms: Animals, Carcinoma, Renal Cell, Cell Division, Chemical and Drug Induced Liver Injury, Combined Modality Therapy, Dose-Response Relationship, Drug, Humans, Interferon-gamma, Kidney Neoplasms, Mice, Mice, Nude, Suramin, Tumor Cells, Cultured, Tumor Necrosis Factor-alpha
Added October 18, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Phenotypic alterations in fibroblasts and fibrosarcoma cells that overexpress latent transforming growth factor-beta 1.
Beauchamp RD, Sheng HM, Bascom CC, Miller DA, Lyons RM, Torre-Amione G, Moses HL
(1992) Endocrinology 130: 2476-86
MeSH Terms: Animals, Blotting, Northern, Cell Line, Embryo, Mammalian, Fibroblasts, Fibrosarcoma, Gene Expression, Kinetics, Mice, Mice, Inbred C3H, Phenotype, Plasmids, Poly A, RNA, RNA, Messenger, Receptors, Cell Surface, Receptors, Transforming Growth Factor beta, Sarcoma, Experimental, Suramin, Transfection, Transforming Growth Factor beta
Added May 3, 2013
0 Communities
1 Members
0 Resources
21 MeSH Terms