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Glutamine-451 Confers Sensitivity to Oxidative Inhibition and Heme-Thiolate Sulfenylation of Cytochrome P450 4B1.
Albertolle ME, Song HD, Wilkey CJ, Segrest JP, Guengerich FP
(2019) Chem Res Toxicol 32: 484-492
MeSH Terms: Animals, Aryl Hydrocarbon Hydroxylases, Glutamine, Heme, Molecular Dynamics Simulation, Mutagenesis, Site-Directed, Oxidation-Reduction, Rabbits, Sulfenic Acids, Sulfhydryl Compounds
Added March 26, 2019
0 Communities
1 Members
0 Resources
10 MeSH Terms
Sulfenylation of Human Liver and Kidney Microsomal Cytochromes P450 and Other Drug-Metabolizing Enzymes as a Response to Redox Alteration.
Albertolle ME, Phan TTN, Pozzi A, Guengerich FP
(2018) Mol Cell Proteomics 17: 889-900
MeSH Terms: Animals, Biocatalysis, Cysteine, Cytochrome P-450 Enzyme System, Humans, Hydrogen Peroxide, Kidney, Mice, Transgenic, Microsomes, Liver, Oxidation-Reduction, Pharmaceutical Preparations, Recombinant Proteins, Staining and Labeling, Sulfenic Acids, Sulfhydryl Compounds
Added March 14, 2018
1 Communities
1 Members
0 Resources
15 MeSH Terms
Trapping redox partnerships in oxidant-sensitive proteins with a small, thiol-reactive cross-linker.
Allan KM, Loberg MA, Chepngeno J, Hurtig JE, Tripathi S, Kang MG, Allotey JK, Widdershins AH, Pilat JM, Sizek HJ, Murphy WJ, Naticchia MR, David JB, Morano KA, West JD
(2016) Free Radic Biol Med 101: 356-366
MeSH Terms: Cross-Linking Reagents, Disulfides, Glutathione Peroxidase, Methionine Sulfoxide Reductases, Oxidants, Oxidation-Reduction, Oxidative Stress, Oxidoreductases Acting on Sulfur Group Donors, Peroxiredoxins, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Sulfhydryl Compounds, Sulfones, Thioredoxins, tert-Butylhydroperoxide
Added April 24, 2017
0 Communities
1 Members
0 Resources
15 MeSH Terms
Nanoscale phase segregation of mixed thiolates on gold nanoparticles.
Harkness KM, Balinski A, McLean JA, Cliffel DE
(2011) Angew Chem Int Ed Engl 50: 10554-9
MeSH Terms: Gold, Metal Nanoparticles, Organogold Compounds, Sulfhydryl Compounds
Added January 20, 2015
0 Communities
1 Members
0 Resources
4 MeSH Terms
ReCLIP (reversible cross-link immuno-precipitation): an efficient method for interrogation of labile protein complexes.
Smith AL, Friedman DB, Yu H, Carnahan RH, Reynolds AB
(2011) PLoS One 6: e16206
MeSH Terms: Cross-Linking Reagents, Immunoprecipitation, Methods, Multiprotein Complexes, Protein Stability, Sulfhydryl Compounds
Added December 12, 2013
2 Communities
2 Members
0 Resources
6 MeSH Terms
A structural mass spectrometry strategy for the relative quantitation of ligands on mixed monolayer-protected gold nanoparticles.
Harkness KM, Hixson BC, Fenn LS, Turner BN, Rape AC, Simpson CA, Huffman BJ, Okoli TC, McLean JA, Cliffel DE
(2010) Anal Chem 82: 9268-74
MeSH Terms: Glutathione, Gold, Hydrophobic and Hydrophilic Interactions, Ligands, Magnetic Resonance Spectroscopy, Mass Spectrometry, Metal Nanoparticles, Polyethylene Glycols, Sulfhydryl Compounds, Surface Properties, Tiopronin
Added January 20, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Unexpected toxicity of monolayer protected gold clusters eliminated by PEG-thiol place exchange reactions.
Simpson CA, Huffman BJ, Gerdon AE, Cliffel DE
(2010) Chem Res Toxicol 23: 1608-16
MeSH Terms: Animals, Female, Gold, Kidney Tubules, Leukocytes, Metal Nanoparticles, Mice, Mice, Inbred BALB C, Polyethylene Glycols, Sulfhydryl Compounds, Water
Added January 20, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Thiol-based, site-specific and covalent immobilization of biomolecules for single-molecule experiments.
Zimmermann JL, Nicolaus T, Neuert G, Blank K
(2010) Nat Protoc 5: 975-85
MeSH Terms: Binding Sites, Enzymes, Immobilized, Fluorescence, Immobilized Proteins, Maleimides, Microscopy, Atomic Force, Nucleic Acids, Polyethylene Glycols, Succinimides, Sulfhydryl Compounds
Added June 2, 2013
0 Communities
1 Members
0 Resources
10 MeSH Terms
Characterization of thiolate-protected gold nanoparticles by mass spectrometry.
Harkness KM, Cliffel DE, McLean JA
(2010) Analyst 135: 868-74
MeSH Terms: Gold, Mass Spectrometry, Metal Nanoparticles, Spectrometry, Mass, Electrospray Ionization, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Sulfhydryl Compounds
Added January 20, 2015
0 Communities
1 Members
0 Resources
6 MeSH Terms
Surface fragmentation of complexes from thiolate protected gold nanoparticles by ion mobility-mass spectrometry.
Harkness KM, Fenn LS, Cliffel DE, McLean JA
(2010) Anal Chem 82: 3061-6
MeSH Terms: Gold, Metal Nanoparticles, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Sulfhydryl Compounds
Added January 20, 2015
0 Communities
1 Members
0 Resources
4 MeSH Terms