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Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples.
Yamazaki H, Inoue K, Shaw PM, Checovich WJ, Guengerich FP, Shimada T
(1997) J Pharmacol Exp Ther 283: 434-42
MeSH Terms: Animals, Anti-Ulcer Agents, Aryl Hydrocarbon Hydroxylases, Cytochrome P-450 CYP2C19, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System, Fluvoxamine, Humans, Hydroxylation, Ketoconazole, Microsomes, Liver, Mixed Function Oxygenases, Omeprazole, Rabbits, Recombinant Proteins, Sulfaphenazole
Added May 26, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae.
Brian WR, Srivastava PK, Umbenhauer DR, Lloyd RS, Guengerich FP
(1989) Biochemistry 28: 4993-9
MeSH Terms: Catalysis, Cytochrome P-450 Enzyme Inhibitors, Cytochrome P-450 Enzyme System, DNA, Electrophoresis, Gene Expression Regulation, Genetic Vectors, Hexobarbital, Humans, Liver, Mephenytoin, Mixed Function Oxygenases, Oxidation-Reduction, Plasmids, Saccharomyces cerevisiae, Spectrophotometry, Ultraviolet, Sulfaphenazole, Tolbutamide
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Roles of human liver cytochrome P4502C and 3A enzymes in the 3-hydroxylation of benzo(a)pyrene.
Yun CH, Shimada T, Guengerich FP
(1992) Cancer Res 52: 1868-74
MeSH Terms: Antibodies, Benzo(a)pyrene, Benzoflavones, Cytochrome P-450 Enzyme System, Gene Expression, Humans, Hydroxylation, Isoenzymes, Kinetics, Liver, Microsomes, Liver, Norpregnenes, Recombinant Proteins, Saccharomyces cerevisiae, Sulfaphenazole
Added March 5, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms