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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 28

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Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes.
Navarro G, Allard C, Morford JJ, Xu W, Liu S, Molinas AJ, Butcher SM, Fine NH, Blandino-Rosano M, Sure VN, Yu S, Zhang R, Münzberg H, Jacobson DA, Katakam PV, Hodson DJ, Bernal-Mizrachi E, Zsombok A, Mauvais-Jarvis F
(2018) JCI Insight 3:
MeSH Terms: Androgens, Animals, Diabetes Mellitus, Type 2, Diet, Western, Dihydrotestosterone, Female, Glucose, Humans, Hyperinsulinism, Hypothalamus, Insulin Resistance, Insulin-Secreting Cells, Mice, Mice, Inbred C57BL, Mice, Knockout, Mitochondria, Neurons, Receptors, Androgen, Streptozocin
Added June 28, 2018
0 Communities
1 Members
0 Resources
19 MeSH Terms
A specific phosphorylation regulates the protective role of αA-crystallin in diabetes.
Ruebsam A, Dulle JE, Myers AM, Sakrikar D, Green KM, Khan NW, Schey K, Fort PE
(2018) JCI Insight 3:
MeSH Terms: Aged, Animals, Cell Line, Crystallins, Diabetes Mellitus, Experimental, Diabetic Retinopathy, Electroretinography, Ependymoglial Cells, Female, Humans, Male, Mice, Mice, Knockout, Neurons, Phosphorylation, Rats, Rats, Sprague-Dawley, Recombinant Proteins, Retina, Streptozocin, Transfection, alpha-Crystallin A Chain, alpha-Crystallin B Chain
Added April 3, 2018
0 Communities
1 Members
0 Resources
23 MeSH Terms
Imbalance between HDAC and HAT activities drives aberrant STAT1/MyD88 expression in macrophages from type 1 diabetic mice.
Filgueiras LR, Brandt SL, Ramalho TR, Jancar S, Serezani CH
(2017) J Diabetes Complications 31: 334-339
MeSH Terms: Acetylation, Animals, Bone Marrow Cells, Cells, Cultured, Diabetes Mellitus, Type 1, Enzyme Inhibitors, Epigenesis, Genetic, Gene Expression Regulation, Glucose, Histone Acetyltransferases, Histone Deacetylases, Histones, Macrophages, Macrophages, Peritoneal, Male, Mice, Inbred C57BL, Myeloid Differentiation Factor 88, Osmolar Concentration, Promoter Regions, Genetic, Protein Processing, Post-Translational, STAT1 Transcription Factor, Streptozocin
Added May 4, 2017
0 Communities
1 Members
0 Resources
22 MeSH Terms
Loss of tumour suppressor PTEN expression in renal injury initiates SMAD3- and p53-dependent fibrotic responses.
Samarakoon R, Helo S, Dobberfuhl AD, Khakoo NS, Falke L, Overstreet JM, Goldschmeding R, Higgins PJ
(2015) J Pathol 236: 421-32
MeSH Terms: Animals, Apoptosis, Aristolochic Acids, Cell Cycle Checkpoints, Cell Line, Cell Proliferation, Disease Models, Animal, Enzyme Inhibitors, Fibrosis, Gene Expression Regulation, Humans, Kidney Diseases, Kidney Tubules, Male, Mice, Inbred C57BL, PTEN Phosphohydrolase, Plasminogen Activator Inhibitor 1, RNA Interference, Signal Transduction, Smad3 Protein, Streptozocin, Transfection, Transforming Growth Factor beta1, Tumor Suppressor Protein p53, Ureteral Obstruction
Added April 19, 2016
0 Communities
1 Members
0 Resources
25 MeSH Terms
Activated FoxM1 attenuates streptozotocin-mediated β-cell death.
Golson ML, Maulis MF, Dunn JC, Poffenberger G, Schug J, Kaestner KH, Gannon MA
(2014) Mol Endocrinol 28: 1435-47
MeSH Terms: Animals, Cell Cycle, Cell Death, Cell Proliferation, Cell Survival, Diabetes Mellitus, Female, Forkhead Box Protein M1, Forkhead Transcription Factors, Immune System, Insulin-Secreting Cells, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Regeneration, Sequence Analysis, RNA, Streptozocin
Added November 25, 2014
1 Communities
1 Members
0 Resources
18 MeSH Terms
Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes.
Al-Hasani K, Pfeifer A, Courtney M, Ben-Othman N, Gjernes E, Vieira A, Druelle N, Avolio F, Ravassard P, Leuckx G, Lacas-Gervais S, Ambrosetti D, Benizri E, Hecksher-Sorensen J, Gounon P, Ferrer J, Gradwohl G, Heimberg H, Mansouri A, Collombat P
(2013) Dev Cell 26: 86-100
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Blood Glucose, Cell Differentiation, Cell Lineage, Cell Movement, Cellular Reprogramming, Diabetes Mellitus, Experimental, Epithelial-Mesenchymal Transition, Gene Expression Regulation, Glucagon-Secreting Cells, Homeodomain Proteins, Hypertrophy, Insulin-Secreting Cells, Mice, Nerve Tissue Proteins, Paired Box Transcription Factors, Pancreatic Ducts, Streptozocin
Added August 14, 2013
0 Communities
0 Members
1 Resources
19 MeSH Terms
Identification of cross-species shared transcriptional networks of diabetic nephropathy in human and mouse glomeruli.
Hodgin JB, Nair V, Zhang H, Randolph A, Harris RC, Nelson RG, Weil EJ, Cavalcoli JD, Patel JM, Brosius FC, Kretzler M
(2013) Diabetes 62: 299-308
MeSH Terms: Adult, Animals, Diabetes Mellitus, Experimental, Diabetic Nephropathies, Gene Regulatory Networks, Humans, Janus Kinases, Kidney Glomerulus, Mice, Mice, Inbred C57BL, Mice, Inbred DBA, Middle Aged, Real-Time Polymerase Chain Reaction, STAT Transcription Factors, Species Specificity, Streptozocin
Added January 28, 2014
1 Communities
1 Members
0 Resources
16 MeSH Terms
Generation of functional insulin-producing cells in the gut by Foxo1 ablation.
Talchai C, Xuan S, Kitamura T, DePinho RA, Accili D
(2012) Nat Genet 44: 406-12, S1
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, C-Peptide, Cell Differentiation, Diabetes Mellitus, Experimental, Enteroendocrine Cells, Forkhead Box Protein O1, Forkhead Transcription Factors, Gastrointestinal Tract, Glucose, Hyperglycemia, Insulin, Insulin Secretion, Insulin-Secreting Cells, Mice, Mice, Transgenic, Nerve Tissue Proteins, Neuroendocrine Cells, Stem Cells, Streptozocin, Sulfonylurea Compounds, Wnt Signaling Pathway
Added April 13, 2012
0 Communities
0 Members
1 Resources
22 MeSH Terms
Reversal of type 1 diabetes in mice by brown adipose tissue transplant.
Gunawardana SC, Piston DW
(2012) Diabetes 61: 674-82
MeSH Terms: Adipose Tissue, Brown, Animals, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 1, Female, Glucose, Homeostasis, Insulin, Interleukin-6, Ion Channels, Mice, Mice, Inbred C57BL, Mitochondrial Proteins, Receptor, Insulin, Streptozocin, Tumor Necrosis Factor-alpha, Uncoupling Protein 1, Weight Gain
Added December 5, 2013
2 Communities
2 Members
0 Resources
18 MeSH Terms
Central insulin resistance and synaptic dysfunction in intracerebroventricular-streptozotocin injected rodents.
Shonesy BC, Thiruchelvam K, Parameshwaran K, Rahman EA, Karuppagounder SS, Huggins KW, Pinkert CA, Amin R, Dhanasekaran M, Suppiramaniam V
(2012) Neurobiol Aging 33: 430.e5-18
MeSH Terms: Alzheimer Disease, Animals, Brain, Humans, Injections, Intraventricular, Insulin Resistance, Long-Term Potentiation, Male, Rats, Rats, Wistar, Receptors, Glutamate, Streptozocin, Synapses, Synaptic Transmission
Added July 2, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms