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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 13

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Perilipin-5 is regulated by statins and controls triglyceride contents in the hepatocyte.
Langhi C, Marquart TJ, Allen RM, Baldán A
(2014) J Hepatol 61: 358-65
MeSH Terms: Animals, Hepatocytes, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Intracellular Signaling Peptides and Proteins, Lipid Droplets, Male, Mice, Mice, Inbred C57BL, Muscle Proteins, Sterol Regulatory Element Binding Protein 2, Triglycerides
Added February 12, 2016
0 Communities
1 Members
0 Resources
11 MeSH Terms
Control of very low-density lipoprotein secretion by N-ethylmaleimide-sensitive factor and miR-33.
Allen RM, Marquart TJ, Jesse JJ, Baldán A
(2014) Circ Res 115: 10-22
MeSH Terms: Animals, Apolipoprotein B-100, Apolipoproteins B, Carrier Proteins, Hepatocytes, Lipoproteins, VLDL, Male, Mice, Mice, Inbred C57BL, MicroRNAs, N-Ethylmaleimide-Sensitive Proteins, Receptors, LDL, Sterol Regulatory Element Binding Protein 2, Triglycerides
Added February 12, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice.
Li Y, Xu S, Mihaylova MM, Zheng B, Hou X, Jiang B, Park O, Luo Z, Lefai E, Shyy JY, Gao B, Wierzbicki M, Verbeuren TJ, Shaw RJ, Cohen RA, Zang M
(2011) Cell Metab 13: 376-388
MeSH Terms: AMP-Activated Protein Kinases, Animals, Atherosclerosis, Benzopyrans, Dietary Fats, Disease Models, Animal, Fatty Liver, Humans, Insulin Resistance, Lipogenesis, Male, Metformin, Mice, Phosphorylation, Receptors, LDL, Sterol Regulatory Element Binding Protein 1, Sterol Regulatory Element Binding Protein 2, Transcription, Genetic
Added July 21, 2014
1 Communities
0 Members
0 Resources
18 MeSH Terms
miR-33 links SREBP-2 induction to repression of sterol transporters.
Marquart TJ, Allen RM, Ory DS, Baldán A
(2010) Proc Natl Acad Sci U S A 107: 12228-32
MeSH Terms: 5' Untranslated Regions, ATP Binding Cassette Transporter 1, ATP Binding Cassette Transporter, Subfamily G, Member 1, ATP-Binding Cassette Transporters, Animals, Base Sequence, Cell Line, Cholesterol, Cholesterol, HDL, Gene Expression Regulation, Humans, Lipoproteins, LDL, Male, Mice, Mice, Inbred C57BL, MicroRNAs, Molecular Sequence Data, RNA, Messenger, Receptors, LDL, Response Elements, Reverse Transcriptase Polymerase Chain Reaction, Sterol Regulatory Element Binding Protein 2, Transcriptional Activation, Transfection
Added February 12, 2016
0 Communities
1 Members
0 Resources
24 MeSH Terms
Hypoxia and the metabolic phenotype of prostate cancer cells.
Higgins LH, Withers HG, Garbens A, Love HD, Magnoni L, Hayward SW, Moyes CD
(2009) Biochim Biophys Acta 1787: 1433-43
MeSH Terms: Animals, Cell Hypoxia, Cell Line, Tumor, Gene Expression, Glycolysis, Humans, Lipids, Male, Mice, Mice, SCID, Mitochondria, Phenotype, Prostatic Neoplasms, Sterol Regulatory Element Binding Protein 2
Added May 27, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Molecular consequences of altered neuronal cholesterol biosynthesis.
Korade Z, Kenworthy AK, Mirnics K
(2009) J Neurosci Res 87: 866-75
MeSH Terms: Animals, Blotting, Northern, Cell Line, Cholesterol, Down-Regulation, Farnesyl-Diphosphate Farnesyltransferase, Fatty Acid Synthases, Fatty Acids, Gene Expression, Gene Expression Profiling, Intracellular Signaling Peptides and Proteins, Mice, Neurons, Oxidoreductases Acting on CH-CH Group Donors, Polymerase Chain Reaction, Proprotein Convertases, RNA, Small Interfering, Serine Endopeptidases, Sterol Regulatory Element Binding Protein 2, Sterols, Transfection, Vesicular Transport Proteins
Added December 10, 2013
0 Communities
2 Members
0 Resources
22 MeSH Terms
The sterol response element binding protein regulates cyclooxygenase-2 gene expression in endothelial cells.
Smith LH, Petrie MS, Morrow JD, Oates JA, Vaughan DE
(2005) J Lipid Res 46: 862-71
MeSH Terms: Animals, Base Sequence, CCAAT-Enhancer-Binding Proteins, Cattle, Cells, Cultured, Cyclooxygenase 2, DNA Primers, DNA-Binding Proteins, Endothelium, Vascular, Epoprostenol, Gene Expression Regulation, Enzymologic, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Lovastatin, Membrane Proteins, Promoter Regions, Genetic, Prostaglandin-Endoperoxide Synthases, Reverse Transcriptase Polymerase Chain Reaction, Sterol Regulatory Element Binding Protein 1, Sterol Regulatory Element Binding Protein 2, Transcription Factors
Added December 10, 2013
0 Communities
1 Members
0 Resources
21 MeSH Terms
Lanosterol metabolism and sterol regulatory element binding protein (SREBP) expression in male germ cell maturation.
Fon Tacer K, Kalanj-Bognar S, Waterman MR, Rozman D
(2003) J Steroid Biochem Mol Biol 85: 429-38
MeSH Terms: Animals, CCAAT-Enhancer-Binding Proteins, DNA-Binding Proteins, Gene Expression Regulation, Lanosterol, Liver, Male, Mice, Mice, Inbred CBA, RNA, Messenger, Reverse Transcriptase Polymerase Chain Reaction, Sexual Maturation, Spermatogenesis, Sterol Regulatory Element Binding Protein 1, Sterol Regulatory Element Binding Protein 2, Testis, Transcription Factors
Added February 12, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes.
Amemiya-Kudo M, Shimano H, Hasty AH, Yahagi N, Yoshikawa T, Matsuzaka T, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Sato R, Kimura S, Ishibashi S, Yamada N
(2002) J Lipid Res 43: 1220-35
MeSH Terms: ATP Citrate (pro-S)-Lyase, Animals, Base Sequence, CCAAT-Enhancer-Binding Proteins, Cholesterol, DNA Primers, DNA-Binding Proteins, Enhancer Elements, Genetic, Fatty Acid Synthases, Glucokinase, Glucosephosphate Dehydrogenase, Humans, Lipids, Malate Dehydrogenase, Mice, Mice, Transgenic, Promoter Regions, Genetic, Pyruvate Kinase, Sterol Regulatory Element Binding Protein 1, Sterol Regulatory Element Binding Protein 2, Transcription Factors, Transcription, Genetic, Tumor Cells, Cultured
Added March 27, 2013
0 Communities
1 Members
0 Resources
23 MeSH Terms
Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs.
Matsuzaka T, Shimano H, Yahagi N, Yoshikawa T, Amemiya-Kudo M, Hasty AH, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Takahashi A, Yato S, Sone H, Ishibashi S, Yamada N
(2002) J Lipid Res 43: 911-20
MeSH Terms: Acyl Coenzyme A, Amino Acid Sequence, Animals, Base Sequence, CCAAT-Enhancer-Binding Proteins, Cell Line, Cloning, Molecular, DNA, Complementary, DNA-Binding Proteins, Fatty Acids, Unsaturated, Gene Expression Regulation, Enzymologic, Humans, Ligands, Liver, Mice, Mice, Transgenic, Molecular Sequence Data, Nutritional Physiological Phenomena, Sequence Alignment, Sterol Regulatory Element Binding Protein 1, Sterol Regulatory Element Binding Protein 2, Substrate Specificity, Tissue Distribution, Transcription Factors
Added March 27, 2013
0 Communities
1 Members
0 Resources
24 MeSH Terms