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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 76

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Oxidation of 7-dehydrocholesterol and desmosterol by human cytochrome P450 46A1.
Goyal S, Xiao Y, Porter NA, Xu L, Guengerich FP
(2014) J Lipid Res 55: 1933-43
MeSH Terms: Cholesterol 24-Hydroxylase, Dehydrocholesterols, Desmosterol, Humans, Kinetics, Oxidation-Reduction, Protein Binding, Steroid Hydroxylases
Added January 20, 2015
0 Communities
1 Members
0 Resources
8 MeSH Terms
Mechanism-based inhibition profiles of erythromycin and clarithromycin with cytochrome P450 3A4 genetic variants.
Akiyoshi T, Ito M, Murase S, Miyazaki M, Guengerich FP, Nakamura K, Yamamoto K, Ohtani H
(2013) Drug Metab Pharmacokinet 28: 411-5
MeSH Terms: Clarithromycin, Cytochrome P-450 CYP3A, Erythromycin, Steroid Hydroxylases
Added March 7, 2014
0 Communities
1 Members
0 Resources
4 MeSH Terms
CYP24A1 and CYP27B1 polymorphisms modulate vitamin D metabolism in colon cancer cells.
Jacobs ET, Van Pelt C, Forster RE, Zaidi W, Hibler EA, Galligan MA, Haussler MR, Jurutka PW
(2013) Cancer Res 73: 2563-73
MeSH Terms: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase, Cell Line, Tumor, Colonic Neoplasms, Enzyme Activation, Humans, Polymorphism, Single Nucleotide, Steroid Hydroxylases, Transcription, Genetic, Vitamin D, Vitamin D3 24-Hydroxylase
Added December 29, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes.
Levin GP, Robinson-Cohen C, de Boer IH, Houston DK, Lohman K, Liu Y, Kritchevsky SB, Cauley JA, Tanaka T, Ferrucci L, Bandinelli S, Patel KV, Hagström E, Michaëlsson K, Melhus H, Wang T, Wolf M, Psaty BM, Siscovick D, Kestenbaum B
(2012) JAMA 308: 1898-905
MeSH Terms: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase, Aged, Chronic Disease, Cohort Studies, Female, Genetic Variation, Genotype, Hip Fractures, Humans, Low Density Lipoprotein Receptor-Related Protein-2, Male, Meta-Analysis as Topic, Myocardial Infarction, Neoplasms, Polymorphism, Single Nucleotide, Receptors, Calcitriol, Receptors, Cell Surface, Risk, Steroid Hydroxylases, Vitamin D, Vitamin D3 24-Hydroxylase
Added September 19, 2017
0 Communities
1 Members
0 Resources
21 MeSH Terms
The serum 24,25-dihydroxyvitamin D concentration, a marker of vitamin D catabolism, is reduced in chronic kidney disease.
Bosworth CR, Levin G, Robinson-Cohen C, Hoofnagle AN, Ruzinski J, Young B, Schwartz SM, Himmelfarb J, Kestenbaum B, de Boer IH
(2012) Kidney Int 82: 693-700
MeSH Terms: African Americans, Aged, Biomarkers, Comorbidity, Cross-Sectional Studies, Down-Regulation, Female, Glomerular Filtration Rate, Humans, Hyperparathyroidism, Secondary, Kaplan-Meier Estimate, Kidney, Linear Models, Male, Mass Spectrometry, Middle Aged, Multivariate Analysis, Parathyroid Hormone, Prognosis, Proportional Hazards Models, Renal Insufficiency, Chronic, Risk Assessment, Risk Factors, Steroid Hydroxylases, Vitamin D, Vitamin D3 24-Hydroxylase, Washington
Added September 19, 2017
0 Communities
1 Members
0 Resources
27 MeSH Terms
Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice.
Morgan JA, Cheepala SB, Wang Y, Neale G, Adachi M, Nachagari D, Leggas M, Zhao W, Boyd K, Venkataramanan R, Schuetz JD
(2012) J Biol Chem 287: 14456-66
MeSH Terms: Animals, Aryl Hydrocarbon Hydroxylases, Cyclic AMP, Cyclic AMP Response Element-Binding Protein, Cytochrome P450 Family 2, Gene Expression Regulation, Enzymologic, Humans, Leydig Cells, Liver, Male, Mice, Mice, Knockout, Multidrug Resistance-Associated Proteins, Receptors, LH, Spermatogenesis, Steroid Hydroxylases, Testosterone, Up-Regulation
Added March 20, 2014
1 Communities
1 Members
0 Resources
18 MeSH Terms
Common variation in vitamin D pathway genes predicts circulating 25-hydroxyvitamin D Levels among African Americans.
Signorello LB, Shi J, Cai Q, Zheng W, Williams SM, Long J, Cohen SS, Li G, Hollis BW, Smith JR, Blot WJ
(2011) PLoS One 6: e28623
MeSH Terms: Adult, African Americans, Aged, Complement System Proteins, Female, Genotype, Humans, Male, Middle Aged, Polymorphism, Single Nucleotide, Receptors, Calcitriol, Signal Transduction, Steroid Hydroxylases, Vitamin D
Added March 18, 2014
0 Communities
3 Members
0 Resources
14 MeSH Terms
Common genetic variants in the vitamin D pathway including genome-wide associated variants are not associated with breast cancer risk among Chinese women.
Dorjgochoo T, Delahanty R, Lu W, Long J, Cai Q, Zheng Y, Gu K, Gao YT, Zheng W, Shu XO
(2011) Cancer Epidemiol Biomarkers Prev 20: 2313-6
MeSH Terms: Adult, Aged, Breast Neoplasms, Case-Control Studies, China, Clinical Trials, Phase I as Topic, Clinical Trials, Phase II as Topic, Female, Follow-Up Studies, Genome-Wide Association Study, Humans, Middle Aged, Polymorphism, Single Nucleotide, Prognosis, Receptors, Calcitriol, Risk Factors, Signal Transduction, Steroid Hydroxylases, Vitamin D, Vitamin D3 24-Hydroxylase
Added December 10, 2013
0 Communities
2 Members
0 Resources
20 MeSH Terms
Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification.
Shen H, Bielak LF, Ferguson JF, Streeten EA, Yerges-Armstrong LM, Liu J, Post W, O'Connell JR, Hixson JE, Kardia SL, Sun YV, Jhun MA, Wang X, Mehta NN, Li M, Koller DL, Hakonarson H, Keating BJ, Rader DJ, Shuldiner AR, Peyser PA, Reilly MP, Mitchell BD
(2010) Arterioscler Thromb Vasc Biol 30: 2648-54
MeSH Terms: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase, Adult, Aged, Calcinosis, Coronary Artery Disease, Female, Gene Frequency, Genetic Predisposition to Disease, Haplotypes, Humans, Linkage Disequilibrium, Male, Middle Aged, Models, Statistical, Phenotype, Polymorphism, Single Nucleotide, Receptors, Calcitriol, Risk Assessment, Risk Factors, Steroid Hydroxylases, United States, Vitamin D, Vitamin D3 24-Hydroxylase, Whites
Added January 20, 2015
0 Communities
1 Members
0 Resources
24 MeSH Terms
Involvement of human cytochrome P450 2B6 in the omega- and 4-hydroxylation of the anesthetic agent propofol.
Murayama N, Minoshima M, Shimizu M, Guengerich FP, Yamazaki H
(2007) Xenobiotica 37: 717-24
MeSH Terms: Anesthetics, Intravenous, Aryl Hydrocarbon Hydroxylases, Humans, Hydroxylation, Microsomes, Liver, Propofol, Steroid Hydroxylases
Added March 26, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms