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Results: 1 to 10 of 160

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Specificity and affinity of the N-terminal residues in staphylocoagulase in binding to prothrombin.
Maddur AA, Kroh HK, Aschenbrenner ME, Gibson BHY, Panizzi P, Sheehan JH, Meiler J, Bock PE, Verhamme IM
(2020) J Biol Chem 295: 5614-5625
MeSH Terms: Bacterial Proteins, Binding Sites, Coagulase, Humans, Models, Molecular, Protein Binding, Prothrombin, Staphylococcal Infections, Staphylococcus aureus, Substrate Specificity
Added March 21, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms
Staphylococcus aureus Osteomyelitis: Bone, Bugs, and Surgery.
Urish KL, Cassat JE
(2020) Infect Immun 88:
MeSH Terms: Animals, Biopsy, Combined Modality Therapy, Disease Management, Disease Susceptibility, Humans, Osteomyelitis, Research, Staphylococcal Infections, Staphylococcus aureus, Symptom Assessment
Added March 25, 2020
0 Communities
1 Members
0 Resources
11 MeSH Terms
Human Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.
Bennett MR, Dong J, Bombardi RG, Soto C, Parrington HM, Nargi RS, Schoeder CT, Nagel MB, Schey KL, Meiler J, Skaar EP, Crowe JE
(2019) mBio 10:
MeSH Terms: Adaptive Immunity, Antibodies, Monoclonal, Crystallography, X-Ray, Humans, Immunity, Humoral, Proteomics, Staphylococcus aureus
Added March 21, 2020
0 Communities
2 Members
0 Resources
7 MeSH Terms
Staphylococcus aureus Infects Osteoclasts and Replicates Intracellularly.
Krauss JL, Roper PM, Ballard A, Shih CC, Fitzpatrick JAJ, Cassat JE, Ng PY, Pavlos NJ, Veis DJ
(2019) mBio 10:
MeSH Terms: Animals, Bacterial Proteins, Cell Differentiation, Cells, Cultured, Female, Macrophages, Male, Mice, Osteoblasts, Osteoclasts, Osteomyelitis, Phagosomes, RANK Ligand, Staphylococcus aureus
Added March 25, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
exhibits heterogeneous siderophore production within the vertebrate host.
Perry WJ, Spraggins JM, Sheldon JR, Grunenwald CM, Heinrichs DE, Cassat JE, Skaar EP, Caprioli RM
(2019) Proc Natl Acad Sci U S A 116: 21980-21982
MeSH Terms: Abscess, Animals, Citrates, Host-Pathogen Interactions, Iron, Mice, Ornithine, Siderophores, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Staphylococcal Infections, Staphylococcus aureus
Added January 22, 2020
0 Communities
3 Members
0 Resources
11 MeSH Terms
Arachidonic Acid Kills Staphylococcus aureus through a Lipid Peroxidation Mechanism.
Beavers WN, Monteith AJ, Amarnath V, Mernaugh RL, Roberts LJ, Chazin WJ, Davies SS, Skaar EP
(2019) mBio 10:
MeSH Terms: Animals, Anti-Bacterial Agents, Arachidonic Acid, Brain, Dose-Response Relationship, Drug, Drug Resistance, Bacterial, Female, Kidney, Lipid Peroxidation, Lipids, Mice, Mice, Inbred BALB C, Microbial Sensitivity Tests, Mutation, Neutrophils, Oxidative Stress, Reactive Oxygen Species, Spleen, Staphylococcal Infections, Staphylococcus aureus, Teichoic Acids
Added March 11, 2020
0 Communities
1 Members
0 Resources
21 MeSH Terms
Identification of Virulence Determinants During Host-Pathogen Interaction Using Tn-Seq Technology.
Peek CT, Ibberson CB, Cassat JE
(2020) Methods Mol Biol 2069: 155-175
MeSH Terms: Animals, DNA Transposable Elements, Gene Library, High-Throughput Nucleotide Sequencing, Mice, Staphylococcal Infections, Staphylococcus aureus, Virulence Factors
Added March 25, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
MicroLESA: Integrating Autofluorescence Microscopy, In Situ Micro-Digestions, and Liquid Extraction Surface Analysis for High Spatial Resolution Targeted Proteomic Studies.
Ryan DJ, Patterson NH, Putnam NE, Wilde AD, Weiss A, Perry WJ, Cassat JE, Skaar EP, Caprioli RM, Spraggins JM
(2019) Anal Chem 91: 7578-7585
MeSH Terms: Animals, Fluorescent Dyes, Kidney, Liquid-Liquid Extraction, Mice, Microscopy, Fluorescence, Peptides, Proteins, Proteomics, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Staphylococcus aureus, Trypsin
Added January 22, 2020
0 Communities
3 Members
0 Resources
12 MeSH Terms
MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis.
Putnam NE, Fulbright LE, Curry JM, Ford CA, Petronglo JR, Hendrix AS, Cassat JE
(2019) PLoS Pathog 15: e1007744
MeSH Terms: Animals, Bone Resorption, Cell Differentiation, Cells, Cultured, Female, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Myeloid Differentiation Factor 88, Osteoclasts, Osteomyelitis, Receptors, Interleukin-1 Type I, Signal Transduction, Staphylococcal Infections, Staphylococcus aureus
Added April 15, 2019
0 Communities
1 Members
0 Resources
16 MeSH Terms
Manganese Detoxification by MntE Is Critical for Resistance to Oxidative Stress and Virulence of .
Grunenwald CM, Choby JE, Juttukonda LJ, Beavers WN, Weiss A, Torres VJ, Skaar EP
(2019) mBio 10:
MeSH Terms: Animals, Cation Transport Proteins, Disease Models, Animal, Gene Expression Regulation, Bacterial, Homeostasis, Iron, Manganese, Mice, Inbred BALB C, Microbial Viability, Oxidative Stress, Staphylococcal Infections, Staphylococcus aureus, Transcription Factors, Transcription, Genetic, Virulence
Added April 2, 2019
0 Communities
1 Members
0 Resources
15 MeSH Terms