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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 21

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DNA methyltransferase 3a and mitogen-activated protein kinase signaling regulate the expression of fibroblast growth factor-inducible 14 (Fn14) during denervation-induced skeletal muscle atrophy.
Tajrishi MM, Shin J, Hetman M, Kumar A
(2014) J Biol Chem 289: 19985-99
MeSH Terms: Animals, Base Sequence, Conserved Sequence, CpG Islands, DNA, DNA (Cytosine-5-)-Methyltransferases, DNA Methylation, Gene Expression, Gene Knockdown Techniques, MAP Kinase Signaling System, Mice, Mice, Inbred C57BL, Models, Biological, Molecular Sequence Data, Muscle Denervation, Muscle, Skeletal, Muscular Atrophy, Promoter Regions, Genetic, RNA, Small Interfering, Receptors, Tumor Necrosis Factor, Sequence Homology, Nucleic Acid, Sp1 Transcription Factor, TWEAK Receptor, Transcription Factor AP-1
Added October 30, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin.
Goswami S, Yee SW, Stocker S, Mosley JD, Kubo M, Castro R, Mefford JA, Wen C, Liang X, Witte J, Brett C, Maeda S, Simpson MD, Hedderson MM, Davis RL, Roden DM, Giacomini KM, Savic RM
(2014) Clin Pharmacol Ther 96: 370-9
MeSH Terms: Adult, Aged, Aged, 80 and over, Biomarkers, Diabetes Mellitus, Type 2, Female, Genome-Wide Association Study, Glycated Hemoglobin A, Hepatocyte Nuclear Factor 4, Homozygote, Humans, Hypoglycemic Agents, Male, Metformin, Middle Aged, Models, Biological, Multivariate Analysis, PPAR alpha, Pharmacogenetics, Phenotype, Polymorphism, Single Nucleotide, Retrospective Studies, Sp1 Transcription Factor, Transcription Factors, Treatment Outcome, United States, Young Adult
Added June 26, 2014
0 Communities
1 Members
0 Resources
27 MeSH Terms
NADPH oxidase deficiency results in reduced alveolar macrophage 5-lipoxygenase expression and decreased leukotriene synthesis.
Coffey MJ, Serezani CH, Phare SM, Flamand N, Peters-Golden M
(2007) J Leukoc Biol 82: 1585-91
MeSH Terms: Animals, Arachidonate 5-Lipoxygenase, Arachidonic Acid, Cells, Cultured, Culture Media, Conditioned, Early Growth Response Protein 1, Leukotrienes, Macrophages, Alveolar, Mice, Mice, Inbred C57BL, Mice, Knockout, NADPH Oxidases, Onium Compounds, Rats, Reactive Oxygen Species, Sp1 Transcription Factor
Added May 4, 2017
0 Communities
1 Members
0 Resources
16 MeSH Terms
Functional zinc finger/sleeping beauty transposase chimeras exhibit attenuated overproduction inhibition.
Wilson MH, Kaminski JM, George AL
(2005) FEBS Lett 579: 6205-9
MeSH Terms: Carrier Proteins, Gene Transfer Techniques, Humans, Mutation, Recombinant Fusion Proteins, Repressor Proteins, Sp1 Transcription Factor, Transposases, Zinc Fingers
Added March 14, 2018
0 Communities
1 Members
0 Resources
9 MeSH Terms
A G/C element mediates repression of the SM22alpha promoter within phenotypically modulated smooth muscle cells in experimental atherosclerosis.
Wamhoff BR, Hoofnagle MH, Burns A, Sinha S, McDonald OG, Owens GK
(2004) Circ Res 95: 981-8
MeSH Terms: Animals, Aorta, Apolipoproteins E, Arteriosclerosis, Becaplermin, Cell Differentiation, Cells, Cultured, Crosses, Genetic, Extracellular Matrix Proteins, Gene Silencing, Genes, Reporter, Hypercholesterolemia, Lac Operon, Mice, Mice, Inbred CBA, Mice, Transgenic, Microfilament Proteins, Muscle Proteins, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, Phenotype, Platelet-Derived Growth Factor, Promoter Regions, Genetic, Protein Binding, Proto-Oncogene Proteins c-sis, Rats, Recombinant Fusion Proteins, Regulatory Sequences, Nucleic Acid, Serum Response Element, Sp1 Transcription Factor
Added May 5, 2016
0 Communities
1 Members
0 Resources
30 MeSH Terms
Common variants at the PCOL2 and Sp1 binding sites of the COL1A1 gene and their interactive effect influence bone mineral density in Caucasians.
Liu PY, Lu Y, Long JR, Xu FH, Shen H, Recker RR, Deng HW
(2004) J Med Genet 41: 752-7
MeSH Terms: Binding Sites, Bone Density, Bone and Bones, Collagen Type I, European Continental Ancestry Group, Female, Genetic Variation, Genotype, Humans, Male, Middle Aged, Polymorphism, Single Nucleotide, Response Elements, Sp1 Transcription Factor
Added December 10, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
TGF-beta1 induction of the adenine nucleotide translocator 1 in astrocytes occurs through Smads and Sp1 transcription factors.
Law AK, Gupta D, Levy S, Wallace DC, McKeon RJ, Buck CR
(2004) BMC Neurosci 5: 1
MeSH Terms: Adenine Nucleotide Translocator 1, Animals, Astrocytes, Binding Sites, Cells, Cultured, Cerebral Cortex, Collodion, DNA-Binding Proteins, Electrophoretic Mobility Shift Assay, Gene Expression Regulation, Implants, Experimental, Mice, Mutagenesis, Site-Directed, Promoter Regions, Genetic, Response Elements, Sequence Deletion, Signal Transduction, Smad2 Protein, Smad3 Protein, Smad4 Protein, Sp1 Transcription Factor, Trans-Activators, Transforming Growth Factor beta, Transforming Growth Factor beta1
Added February 28, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
High glucose and insulin promote O-GlcNAc modification of proteins, including alpha-tubulin.
Walgren JL, Vincent TS, Schey KL, Buse MG
(2003) Am J Physiol Endocrinol Metab 284: E424-34
MeSH Terms: Acetylglucosamine, Animals, Cells, Cultured, Glucose, Glycosylation, HSP70 Heat-Shock Proteins, Hypoglycemic Agents, Insulin, Insulin Resistance, Mass Spectrometry, Membrane Proteins, Muscle Cells, Sp1 Transcription Factor, Tubulin
Added May 27, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Regulation of plasminogen activator inhibitor-1 expression by transforming growth factor-beta -induced physical and functional interactions between smads and Sp1.
Datta PK, Blake MC, Moses HL
(2000) J Biol Chem 275: 40014-9
MeSH Terms: Animals, Cell Line, DNA-Binding Proteins, Gene Expression Regulation, Humans, Plasminogen Activator Inhibitor 1, Smad3 Protein, Smad4 Protein, Sp1 Transcription Factor, Trans-Activators, Transforming Growth Factor beta
Added February 17, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Dynamic expression and activity of NF-kappaB during post-natal mammary gland morphogenesis.
Brantley DM, Yull FE, Muraoka RS, Hicks DJ, Cook CM, Kerr LD
(2000) Mech Dev 97: 149-55
MeSH Terms: Animals, Cell Nucleus, Cytoplasm, DNA-Binding Proteins, Female, Humans, I-kappa B Proteins, Mammary Glands, Animal, Mice, Mice, Inbred C57BL, Morphogenesis, NF-KappaB Inhibitor alpha, NF-kappa B, NF-kappa B p50 Subunit, Pregnancy, Protein Precursors, Sp1 Transcription Factor, Transcription Factor RelA, Tubulin
Added March 5, 2014
0 Communities
3 Members
0 Resources
19 MeSH Terms