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Results: 1 to 10 of 17

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Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders.
Bryan MR, Bowman AB
(2017) Adv Neurobiol 18: 113-142
MeSH Terms: Alzheimer Disease, Amyotrophic Lateral Sclerosis, Animals, Autophagy, Brain, Disease Models, Animal, Humans, Huntingtin Protein, Huntington Disease, Insulin, Manganese, Mitochondria, Neostriatum, Neural Stem Cells, Neurodegenerative Diseases, Parkinson Disease, Reactive Oxygen Species, Signal Transduction, Somatomedins
Added April 11, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Rare and low-frequency coding variants alter human adult height.
Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y, Schurmann C, Highland HM, Rüeger S, Thorleifsson G, Justice AE, Lamparter D, Stirrups KE, Turcot V, Young KL, Winkler TW, Esko T, Karaderi T, Locke AE, Masca NG, Ng MC, Mudgal P, Rivas MA, Vedantam S, Mahajan A, Guo X, Abecasis G, Aben KK, Adair LS, Alam DS, Albrecht E, Allin KH, Allison M, Amouyel P, Appel EV, Arveiler D, Asselbergs FW, Auer PL, Balkau B, Banas B, Bang LE, Benn M, Bergmann S, Bielak LF, Blüher M, Boeing H, Boerwinkle E, Böger CA, Bonnycastle LL, Bork-Jensen J, Bots ML, Bottinger EP, Bowden DW, Brandslund I, Breen G, Brilliant MH, Broer L, Burt AA, Butterworth AS, Carey DJ, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Chowdhury R, Christensen C, Chu AY, Cocca M, Collins FS, Cook JP, Corley J, Galbany JC, Cox AJ, Cuellar-Partida G, Danesh J, Davies G, de Bakker PI, de Borst GJ, de Denus S, de Groot MC, de Mutsert R, Deary IJ, Dedoussis G, Demerath EW, den Hollander AI, Dennis JG, Di Angelantonio E, Drenos F, Du M, Dunning AM, Easton DF, Ebeling T, Edwards TL, Ellinor PT, Elliott P, Evangelou E, Farmaki AE, Faul JD, Feitosa MF, Feng S, Ferrannini E, Ferrario MM, Ferrieres J, Florez JC, Ford I, Fornage M, Franks PW, Frikke-Schmidt R, Galesloot TE, Gan W, Gandin I, Gasparini P, Giedraitis V, Giri A, Girotto G, Gordon SD, Gordon-Larsen P, Gorski M, Grarup N, Grove ML, Gudnason V, Gustafsson S, Hansen T, Harris KM, Harris TB, Hattersley AT, Hayward C, He L, Heid IM, Heikkilä K, Helgeland Ø, Hernesniemi J, Hewitt AW, Hocking LJ, Hollensted M, Holmen OL, Hovingh GK, Howson JM, Hoyng CB, Huang PL, Hveem K, Ikram MA, Ingelsson E, Jackson AU, Jansson JH, Jarvik GP, Jensen GB, Jhun MA, Jia Y, Jiang X, Johansson S, Jørgensen ME, Jørgensen T, Jousilahti P, Jukema JW, Kahali B, Kahn RS, Kähönen M, Kamstrup PR, Kanoni S, Kaprio J, Karaleftheri M, Kardia SL, Karpe F, Kee F, Keeman R, Kiemeney LA, Kitajima H, Kluivers KB, Kocher T, Komulainen P, Kontto J, Kooner JS, Kooperberg C, Kovacs P, Kriebel J, Kuivaniemi H, Küry S, Kuusisto J, La Bianca M, Laakso M, Lakka TA, Lange EM, Lange LA, Langefeld CD, Langenberg C, Larson EB, Lee IT, Lehtimäki T, Lewis CE, Li H, Li J, Li-Gao R, Lin H, Lin LA, Lin X, Lind L, Lindström J, Linneberg A, Liu Y, Liu Y, Lophatananon A, Luan J, Lubitz SA, Lyytikäinen LP, Mackey DA, Madden PA, Manning AK, Männistö S, Marenne G, Marten J, Martin NG, Mazul AL, Meidtner K, Metspalu A, Mitchell P, Mohlke KL, Mook-Kanamori DO, Morgan A, Morris AD, Morris AP, Müller-Nurasyid M, Munroe PB, Nalls MA, Nauck M, Nelson CP, Neville M, Nielsen SF, Nikus K, Njølstad PR, Nordestgaard BG, Ntalla I, O'Connel JR, Oksa H, Loohuis LM, Ophoff RA, Owen KR, Packard CJ, Padmanabhan S, Palmer CN, Pasterkamp G, Patel AP, Pattie A, Pedersen O, Peissig PL, Peloso GM, Pennell CE, Perola M, Perry JA, Perry JR, Person TN, Pirie A, Polasek O, Posthuma D, Raitakari OT, Rasheed A, Rauramaa R, Reilly DF, Reiner AP, Renström F, Ridker PM, Rioux JD, Robertson N, Robino A, Rolandsson O, Rudan I, Ruth KS, Saleheen D, Salomaa V, Samani NJ, Sandow K, Sapkota Y, Sattar N, Schmidt MK, Schreiner PJ, Schulze MB, Scott RA, Segura-Lepe MP, Shah S, Sim X, Sivapalaratnam S, Small KS, Smith AV, Smith JA, Southam L, Spector TD, Speliotes EK, Starr JM, Steinthorsdottir V, Stringham HM, Stumvoll M, Surendran P, 't Hart LM, Tansey KE, Tardif JC, Taylor KD, Teumer A, Thompson DJ, Thorsteinsdottir U, Thuesen BH, Tönjes A, Tromp G, Trompet S, Tsafantakis E, Tuomilehto J, Tybjaerg-Hansen A, Tyrer JP, Uher R, Uitterlinden AG, Ulivi S, van der Laan SW, Van Der Leij AR, van Duijn CM, van Schoor NM, van Setten J, Varbo A, Varga TV, Varma R, Edwards DR, Vermeulen SH, Vestergaard H, Vitart V, Vogt TF, Vozzi D, Walker M, Wang F, Wang CA, Wang S, Wang Y, Wareham NJ, Warren HR, Wessel J, Willems SM, Wilson JG, Witte DR, Woods MO, Wu Y, Yaghootkar H, Yao J, Yao P, Yerges-Armstrong LM, Young R, Zeggini E, Zhan X, Zhang W, Zhao JH, Zhao W, Zhao W, Zheng H, Zhou W, EPIC-InterAct Consortium, CHD Exome+ Consortium, ExomeBP Consortium, T2D-Genes Consortium, GoT2D Genes Consortium, Global Lipids Genetics Consortium, ReproGen Consortium, MAGIC Investigators, Rotter JI, Boehnke M, Kathiresan S, McCarthy MI, Willer CJ, Stefansson K, Borecki IB, Liu DJ, North KE, Heard-Costa NL, Pers TH, Lindgren CM, Oxvig C, Kutalik Z, Rivadeneira F, Loos RJ, Frayling TM, Hirschhorn JN, Deloukas P, Lettre G
(2017) Nature 542: 186-190
MeSH Terms: ADAMTS Proteins, Adult, Alleles, Body Height, Cell Adhesion Molecules, Female, Gene Frequency, Genetic Variation, Genome, Human, Glycoproteins, Glycosaminoglycans, Hedgehog Proteins, Humans, Intercellular Signaling Peptides and Proteins, Interferon Regulatory Factors, Interleukin-11 Receptor alpha Subunit, Male, Multifactorial Inheritance, NADPH Oxidase 4, NADPH Oxidases, Phenotype, Pregnancy-Associated Plasma Protein-A, Procollagen N-Endopeptidase, Proteoglycans, Proteolysis, Receptors, Androgen, Somatomedins
Added April 26, 2017
0 Communities
1 Members
0 Resources
27 MeSH Terms
Prospects and challenges for the development of new therapies for Ewing sarcoma.
Grohar PJ, Helman LJ
(2013) Pharmacol Ther 137: 216-24
MeSH Terms: Antineoplastic Agents, Bone Neoplasms, Camptothecin, Clinical Trials as Topic, Dioxoles, Epigenesis, Genetic, Humans, Molecular Targeted Therapy, Poly(ADP-ribose) Polymerase Inhibitors, Sarcoma, Ewing, Somatomedins, Tetrahydroisoquinolines, Trabectedin
Added September 3, 2013
0 Communities
2 Members
0 Resources
13 MeSH Terms
Insulin resistance in critically ill patients with acute renal failure.
Basi S, Pupim LB, Simmons EM, Sezer MT, Shyr Y, Freedman S, Chertow GM, Mehta RL, Paganini E, Himmelfarb J, Ikizler TA
(2005) Am J Physiol Renal Physiol 289: F259-64
MeSH Terms: Acute Kidney Injury, Adolescent, Adult, Aged, Blood Glucose, Critical Illness, Female, Hemodynamics, Humans, Hyperglycemia, Hyperinsulinism, Insulin, Insulin Resistance, Insulin-Like Growth Factor Binding Protein 1, Insulin-Like Growth Factor Binding Protein 3, Logistic Models, Male, Middle Aged, Predictive Value of Tests, Signal Transduction, Somatomedins, Survivors
Added September 29, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Joint effect of insulin-like growth factors and sex steroids on breast cancer risk.
Yu H, Shu XO, Li BD, Dai Q, Gao YT, Jin F, Zheng W
(2003) Cancer Epidemiol Biomarkers Prev 12: 1067-73
MeSH Terms: Adult, Breast Neoplasms, Case-Control Studies, Estrogens, Female, Humans, Middle Aged, Regression Analysis, Risk Factors, Somatomedins, Testosterone
Added December 10, 2013
0 Communities
2 Members
0 Resources
11 MeSH Terms
Repair of metabolic processes.
Shipman J, Guy J, Abumrad NN
(2003) Crit Care Med 31: S512-7
MeSH Terms: Acute-Phase Reaction, Autonomic Nervous System, Critical Illness, Energy Metabolism, Growth Hormone, Homeostasis, Humans, Hypothalamo-Hypophyseal System, Inflammation Mediators, Insulin, Somatomedins, Systemic Inflammatory Response Syndrome, T-Lymphocytes
Added December 10, 2013
0 Communities
1 Members
0 Resources
13 MeSH Terms
Inhibition of the mitogenic effects of plasma by a monoclonal antibody to somatomedin C.
Russell WE, Van Wyk JJ, Pledger WJ
(1984) Proc Natl Acad Sci U S A 81: 2389-92
MeSH Terms: Animals, Antibodies, Monoclonal, Antigen-Antibody Complex, Blood, Cattle, Cells, Cultured, Culture Media, DNA Replication, Epidermal Growth Factor, Insulin, Insulin-Like Growth Factor I, Kinetics, Mice, Mice, Inbred BALB C, Mitogens, Somatomedins
Added December 10, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
Synthetic somatomedin C: comparison with natural hormone isolated from human plasma.
Van Wyk JJ, Russell WE, Li CH
(1984) Proc Natl Acad Sci U S A 81: 740-2
MeSH Terms: Animals, Antibodies, Monoclonal, Biological Assay, Cells, Cultured, DNA Replication, Epidermal Growth Factor, Humans, Insulin, Insulin-Like Growth Factor I, Mice, Mice, Inbred BALB C, Radioimmunoassay, Somatomedins
Added December 10, 2013
0 Communities
1 Members
0 Resources
13 MeSH Terms
Somatomedin C/insulinlike growth factor I during liver regeneration in the rat.
Russell WE, D'Ercole AJ, Underwood LE
(1985) Am J Physiol 248: E618-23
MeSH Terms: Animals, DNA Replication, Energy Intake, Food Deprivation, Insulin-Like Growth Factor I, Kidney, Liver, Liver Regeneration, Lung, Male, Rats, Rats, Inbred Strains, Somatomedins
Added December 10, 2013
0 Communities
1 Members
0 Resources
13 MeSH Terms
Expression of a biologically active analogue of somatomedin-C/insulin-like growth factor I.
Peters MA, Lau EP, Snitman DL, Van Wyk JJ, Underwood LE, Russell WE, Svoboda ME
(1985) Gene 35: 83-9
MeSH Terms: Animals, Cell Division, Cloning, Molecular, DNA, Recombinant, Escherichia coli, Humans, Insulin, Insulin-Like Growth Factor I, Mice, Mitogens, Operon, Peptide Biosynthesis, Peptides, Plasmids, Somatomedins
Added December 10, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms