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Results: 1 to 10 of 10

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Prophylactic and therapeutic testing of Nicotiana-derived RSV-neutralizing human monoclonal antibodies in the cotton rat model.
Zeitlin L, Bohorov O, Bohorova N, Hiatt A, Kim DH, Pauly MH, Velasco J, Whaley KJ, Barnard DL, Bates JT, Crowe JE, Piedra PA, Gilbert BE
(2013) MAbs 5: 263-9
MeSH Terms: Animals, Antibodies, Monoclonal, Humanized, Antibodies, Neutralizing, Disease Models, Animal, Humans, Palivizumab, Respiratory Syncytial Virus Infections, Respiratory Syncytial Virus, Human, Sigmodontinae, Tobacco, Treatment Outcome
Added January 26, 2016
0 Communities
1 Members
0 Resources
11 MeSH Terms
An alphavirus replicon-based human metapneumovirus vaccine is immunogenic and protective in mice and cotton rats.
Mok H, Tollefson SJ, Podsiad AB, Shepherd BE, Polosukhin VV, Johnston RE, Williams JV, Crowe JE
(2008) J Virol 82: 11410-8
MeSH Terms: Administration, Intranasal, Animals, Antibodies, Viral, Cell Line, Encephalitis Virus, Venezuelan Equine, Immunoglobulin A, Immunoglobulin G, Lung, Macaca mulatta, Metapneumovirus, Mice, Mice, Inbred DBA, Mucous Membrane, Neutralization Tests, Paramyxoviridae Infections, Rats, Respiratory System, Sigmodontinae, Viral Structural Proteins, Viral Vaccines
Added August 6, 2012
0 Communities
1 Members
0 Resources
20 MeSH Terms
Respiratory syncytial virus (RSV) fusion protein expressed by recombinant Sendai virus elicits B-cell and T-cell responses in cotton rats and confers protection against RSV subtypes A and B.
Zhan X, Hurwitz JL, Krishnamurthy S, Takimoto T, Boyd K, Scroggs RA, Surman S, Portner A, Slobod KS
(2007) Vaccine 25: 8782-93
MeSH Terms: Amino Acid Sequence, Animals, Antibodies, Viral, Enzyme-Linked Immunosorbent Assay, Female, Humans, Interferon-gamma, Lung, Molecular Sequence Data, Neutralization Tests, Respiratory Syncytial Virus Infections, Respiratory Syncytial Viruses, Sendai virus, Sigmodontinae, T-Lymphocytes, Vaccines, Synthetic, Viral Envelope Proteins, Viral Fusion Proteins, Viral Plaque Assay, Viral Vaccines
Added March 5, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Venezuelan equine encephalitis virus replicon particles encoding respiratory syncytial virus surface glycoproteins induce protective mucosal responses in mice and cotton rats.
Mok H, Lee S, Utley TJ, Shepherd BE, Polosukhin VV, Collier ML, Davis NL, Johnston RE, Crowe JE
(2007) J Virol 81: 13710-22
MeSH Terms: Animals, Cell Line, Cricetinae, Encephalitis Virus, Venezuelan Equine, Immunity, Mucosal, Lung, Mice, Mice, Inbred BALB C, Replicon, Respiratory Syncytial Virus Infections, Respiratory Syncytial Virus Vaccines, Respiratory Syncytial Virus, Human, Sigmodontinae, Vaccination, Viral Envelope Proteins, Viral Fusion Proteins, Virion
Added August 6, 2012
0 Communities
1 Members
0 Resources
17 MeSH Terms
A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo.
Williams JV, Chen Z, Cseke G, Wright DW, Keefer CJ, Tollefson SJ, Hessell A, Podsiad A, Shepherd BE, Sanna PP, Burton DR, Crowe JE, Williamson RA
(2007) J Virol 81: 8315-24
MeSH Terms: Animals, Antibodies, Monoclonal, Cell Line, Epitopes, Humans, Immunoglobulin Fab Fragments, Infant, Metapneumovirus, Neutralization Tests, Paramyxoviridae Infections, Peptide Library, Rats, Recombinant Proteins, Sigmodontinae, Viral Fusion Proteins, Viral Load
Added August 6, 2012
0 Communities
1 Members
0 Resources
16 MeSH Terms
Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats.
Cseke G, Wright DW, Tollefson SJ, Johnson JE, Crowe JE, Williams JV
(2007) J Virol 81: 698-707
MeSH Terms: Animals, Antibodies, Viral, Cell Line, Disease Models, Animal, Humans, Immunization, Lung, Metapneumovirus, Paramyxoviridae Infections, Respiratory Tract Infections, Sigmodontinae, Viral Fusion Proteins, Viral Vaccines
Added August 6, 2012
0 Communities
1 Members
0 Resources
13 MeSH Terms
The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity.
Williams JV, Tollefson SJ, Johnson JE, Crowe JE
(2005) J Virol 79: 10944-51
MeSH Terms: Animals, Antibodies, Viral, Cricetinae, Disease Models, Animal, Guinea Pigs, Inflammation, Lung, Metapneumovirus, Mice, Nasal Mucosa, Neutralization Tests, Paramyxoviridae Infections, Rats, Respiratory Mucosa, Respiratory System, Respiratory Tract Infections, Sigmodontinae
Added August 6, 2012
0 Communities
1 Members
0 Resources
17 MeSH Terms
Recombinant Sendai virus expressing the G glycoprotein of respiratory syncytial virus (RSV) elicits immune protection against RSV.
Takimoto T, Hurwitz JL, Coleclough C, Prouser C, Krishnamurthy S, Zhan X, Boyd K, Scroggs RA, Brown B, Nagai Y, Portner A, Slobod KS
(2004) J Virol 78: 6043-7
MeSH Terms: Animals, Immunization, Respiratory Syncytial Virus Vaccines, Sendai virus, Sigmodontinae, Vaccines, Synthetic, Viral Proteins
Added March 20, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
Live subgroup B respiratory syncytial virus vaccines that are attenuated, genetically stable, and immunogenic in rodents and nonhuman primates.
Crowe JE, Bui PT, Firestone CY, Connors M, Elkins WR, Chanock RM, Murphy BR
(1996) J Infect Dis 173: 829-39
MeSH Terms: Animals, Antibodies, Viral, Chlorocebus aethiops, Mutagenesis, Respiratory Syncytial Virus Infections, Respiratory Syncytial Viruses, Serotyping, Sigmodontinae, Vaccines, Attenuated, Viral Vaccines, Virus Replication
Added August 6, 2012
0 Communities
1 Members
0 Resources
11 MeSH Terms
An update on approaches to the development of respiratory syncytial virus (RSV) and parainfluenza virus type 3 (PIV3) vaccines.
Murphy BR, Hall SL, Kulkarni AB, Crowe JE, Collins PL, Connors M, Karron RA, Chanock RM
(1994) Virus Res 32: 13-36
MeSH Terms: Adult, Animals, Antibodies, Anti-Idiotypic, Antibodies, Viral, Clinical Trials as Topic, Humans, ISCOMs, Immunity, Maternally-Acquired, Infant, Infant, Newborn, Influenza Vaccines, Influenza, Human, Mice, Pan troglodytes, Parainfluenza Virus 3, Human, Peptide Fragments, Respiratory Syncytial Virus Infections, Respiratory Syncytial Viruses, Sigmodontinae, Vaccination, Vaccines, Attenuated, Vaccines, Synthetic, Viral Vaccines
Added August 6, 2012
0 Communities
1 Members
0 Resources
23 MeSH Terms