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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 23

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Real-time visualization of titin dynamics reveals extensive reversible photobleaching in human induced pluripotent stem cell-derived cardiomyocytes.
Cadar AG, Feaster TK, Bersell KR, Wang L, Hong T, Balsamo JA, Zhang Z, Chun YW, Nam YJ, Gotthardt M, Knollmann BC, Roden DM, Lim CC, Hong CC
(2020) Am J Physiol Cell Physiol 318: C163-C173
MeSH Terms: Adult, Cell Differentiation, Cell Line, Connectin, Fluorescence Recovery After Photobleaching, Humans, Induced Pluripotent Stem Cells, Kinetics, Luminescent Proteins, Male, Microscopy, Fluorescence, Microscopy, Video, Myocytes, Cardiac, Recombinant Fusion Proteins, Reproducibility of Results, Sarcomeres
Added March 24, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
Ensuring expression of four core cardiogenic transcription factors enhances cardiac reprogramming.
Zhang Z, Zhang AD, Kim LJ, Nam YJ
(2019) Sci Rep 9: 6362
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Differentiation, Cells, Cultured, Cellular Reprogramming, Fibroblasts, GATA4 Transcription Factor, Gene Expression, MEF2 Transcription Factors, Mice, Inbred C57BL, Mice, Transgenic, Muscle Proteins, Myocytes, Cardiac, Sarcomeres, T-Box Domain Proteins, Transcription Factors
Added March 24, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
Muscle-specific stress fibers give rise to sarcomeres in cardiomyocytes.
Fenix AM, Neininger AC, Taneja N, Hyde K, Visetsouk MR, Garde RJ, Liu B, Nixon BR, Manalo AE, Becker JR, Crawley SW, Bader DM, Tyska MJ, Liu Q, Gutzman JH, Burnette DT
(2018) Elife 7:
MeSH Terms: Actin Cytoskeleton, Actins, Cell Line, Cell Line, Tumor, Formins, HeLa Cells, Humans, Microfilament Proteins, Microscopy, Confocal, Molecular Motor Proteins, Muscle Fibers, Skeletal, Myocytes, Cardiac, Myosin Heavy Chains, Nonmuscle Myosin Type IIB, RNA Interference, Sarcomeres, Stress Fibers
Added March 27, 2019
0 Communities
1 Members
0 Resources
17 MeSH Terms
A Missense Variant in PLEC Increases Risk of Atrial Fibrillation.
Thorolfsdottir RB, Sveinbjornsson G, Sulem P, Helgadottir A, Gretarsdottir S, Benonisdottir S, Magnusdottir A, Davidsson OB, Rajamani S, Roden DM, Darbar D, Pedersen TR, Sabatine MS, Jonsdottir I, Arnar DO, Thorsteinsdottir U, Gudbjartsson DF, Holm H, Stefansson K
(2017) J Am Coll Cardiol 70: 2157-2168
MeSH Terms: Atrial Fibrillation, Electrocardiography, Genome-Wide Association Study, Genomic Structural Variation, Humans, Mutation, Missense, Myosin Light Chains, Plectin, Risk, Sarcomeres
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells.
Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, Wu SM, Moslehi JJ, Mercola M, Wu JC
(2017) Sci Transl Med 9:
MeSH Terms: Biomarkers, Cardiotoxicity, Fibroblasts, High-Throughput Screening Assays, Humans, Induced Pluripotent Stem Cells, Insulin, Insulin-Like Growth Factor I, Models, Biological, Myocytes, Cardiac, Phosphorylation, Protein Kinase Inhibitors, Sarcomeres, Signal Transduction, Vascular Endothelial Growth Factor Receptor-2
Added March 26, 2017
0 Communities
1 Members
0 Resources
15 MeSH Terms
Differential responses of induced pluripotent stem cell-derived cardiomyocytes to anisotropic strain depends on disease status.
Chun YW, Voyles DE, Rath R, Hofmeister LH, Boire TC, Wilcox H, Lee JH, Bellan LM, Hong CC, Sung HJ
(2015) J Biomech 48: 3890-6
MeSH Terms: Biomarkers, Cardiac Myosins, Cardiomyopathy, Dilated, Cell Culture Techniques, Cell Differentiation, Extracellular Matrix, Humans, Induced Pluripotent Stem Cells, Myocytes, Cardiac, Myosin Light Chains, Sarcomeres, Stress, Mechanical, Troponin T
Added October 21, 2015
1 Communities
2 Members
0 Resources
13 MeSH Terms
Research priorities in sarcomeric cardiomyopathies.
van der Velden J, Ho CY, Tardiff JC, Olivotto I, Knollmann BC, Carrier L
(2015) Cardiovasc Res 105: 449-56
MeSH Terms: Animals, Biomedical Research, Cardiology, Cardiomyopathies, Genetic Markers, Genetic Predisposition to Disease, Humans, Mutation, Phenotype, Research, Sarcomeres
Added February 12, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes.
Eschenhagen T, Mummery C, Knollmann BC
(2015) Cardiovasc Res 105: 424-38
MeSH Terms: Animals, Cardiomyopathies, Cell Differentiation, Cells, Cultured, Genetic Markers, Genetic Predisposition to Disease, Humans, Induced Pluripotent Stem Cells, Models, Cardiovascular, Mutation, Myocytes, Cardiac, Phenotype, Sarcomeres, Translational Medical Research
Added February 12, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Upstream open reading frame in 5'-untranslated region reduces titin mRNA translational efficiency.
Cadar AG, Zhong L, Lin A, Valenzuela MO, Lim CC
(2014) Biochem Biophys Res Commun 453: 185-91
MeSH Terms: 5' Untranslated Regions, Animals, Base Sequence, Cell Line, Connectin, Doxorubicin, Gene Expression Regulation, HEK293 Cells, Half-Life, Humans, Mice, Molecular Sequence Data, Myocytes, Cardiac, Open Reading Frames, Polymorphism, Single Nucleotide, Protein Kinases, RNA Stability, RNA, Messenger, Rats, Sarcomeres, Sequence Homology, Nucleic Acid
Added February 19, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Familial hypertrophic cardiomyopathy: is the Frank-Starling law kaput?
Huke S, Knollmann BC
(2013) Circ Res 112: 1409-11
MeSH Terms: Animals, Cardiomyopathy, Hypertrophic, Female, Humans, Male, Myofibrils, Sarcomeres
Added May 27, 2014
0 Communities
2 Members
0 Resources
7 MeSH Terms