Search Vanderbilt Publications

Revisiting Some Useful Statistical Guidelines in in Response to a Changing Landscape.
Highland HM, Gamazon ER, Below JE
(2021) Circ Res 128: 1724-1727
MeSH Terms: American Heart Association, Control Groups, Correlation of Data, Data Analysis, Data Display, Data Interpretation, Statistical, Genomics, Information Dissemination, Periodicals as Topic, Probability, Sample Size, United States
Added May 26, 2021

Opportunities and Challenges in Cardiovascular Pharmacogenomics: From Discovery to Implementation.
Roden DM, Van Driest SL, Wells QS, Mosley JD, Denny JC, Peterson JF
(2018) Circ Res 122: 1176-1190
MeSH Terms: Biological Variation, Individual, Biotransformation, Cardiovascular Agents, Drug Development, Drug-Related Side Effects and Adverse Reactions, Forecasting, Genetic Association Studies, Genetic Predisposition to Disease, Genetic Testing, Genetic Variation, Genomics, Genotyping Techniques, Human Genome Project, Humans, Pharmacogenetics, Precision Medicine, Randomized Controlled Trials as Topic, Risk Assessment, Sample Size
Added March 24, 2020

The genetic architecture of type 2 diabetes.
Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Müller-Nurasyid M, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Varga TV, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Nagai Y, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Stančáková A, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Thuillier D, Lim WY, Liu J, van der Schouw YT, Loh M, Musani SK, Puppala S, Scott WR, Yengo L, Tan ST, Taylor HA, Thameem F, Wilson G, Wong TY, Njølstad PR, Levy JC, Mangino M, Bonnycastle LL, Schwarzmayr T, Fadista J, Surdulescu GL, Herder C, Groves CJ, Wieland T, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney ASF, Kinnunen L, Esko T, Farmer AJ, Hakaste L, Hodgkiss D, Kravic J, Lyssenko V, Hollensted M, Jørgensen ME, Jørgensen T, Ladenvall C, Justesen JM, Käräjämäki A, Kriebel J, Rathmann W, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Melander O, Milani L, Neville M, Orho-Melander M, Qi L, Qi Q, Roden M, Rolandsson O, Swift A, Rosengren AH, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, de Angelis MH, Deloukas P, Gjesing AP, Jun G, Nilsson P, Murphy J, Onofrio R, Thorand B, Hansen T, Meisinger C, Hu FB, Isomaa B, Karpe F, Liang L, Peters A, Huth C, O'Rahilly SP, Palmer CNA, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Syvänen AC, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JCN, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RCW, Pollin TI, Sandhu M, Tandon N, Froguel P, Barroso I, Teo YY, Zeggini E, Loos RJF, Small KS, Ried JS, DeFronzo RA, Grallert H, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Gieger C, Ingelsson E, Im HK, Illig T, Franks PW, Buck G, Trakalo J, Buck D, Prokopenko I, Mägi R, Lind L, Farjoun Y, Owen KR, Gloyn AL, Strauch K, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Strom TM, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Burtt NP, Mohlke KL, Meitinger T, Groop L, Abecasis G, Florez JC, Scott LJ, Morris AP, Kang HM, Boehnke M, Altshuler D, McCarthy MI
(2016) Nature 536: 41-47
MeSH Terms: Alleles, DNA Mutational Analysis, Diabetes Mellitus, Type 2, Europe, Exome, Genetic Predisposition to Disease, Genetic Variation, Genome-Wide Association Study, Genotyping Techniques, Humans, Sample Size
Added April 13, 2017

Continuously moving table MRI with golden angle radial sampling.
Sengupta S, Smith DS, Welch EB
(2015) Magn Reson Med 74: 1690-7
MeSH Terms: Algorithms, Beds, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Magnetic Resonance Imaging, Patient Positioning, Phantoms, Imaging, Reproducibility of Results, Sample Size, Sensitivity and Specificity, Whole Body Imaging
Added January 20, 2015

Size matters: how population size influences genotype-phenotype association studies in anonymized data.
Heatherly R, Denny JC, Haines JL, Roden DM, Malin BA
(2014) J Biomed Inform 52: 243-50
MeSH Terms: Algorithms, Biomedical Research, Computer Simulation, Confidentiality, Databases, Genetic, Electronic Health Records, Genetic Association Studies, Genotype, Humans, Phenotype, Polymorphism, Single Nucleotide, Sample Size
Added March 14, 2018

Using ancestry-informative markers to identify fine structure across 15 populations of European origin.
Huckins LM, Boraska V, Franklin CS, Floyd JA, Southam L, GCAN, WTCCC3, Sullivan PF, Bulik CM, Collier DA, Tyler-Smith C, Zeggini E, Tachmazidou I, GCAN, WTCCC3
(2014) Eur J Hum Genet 22: 1190-200
MeSH Terms: Anorexia Nervosa, Gene Frequency, Genetic Markers, Genetics, Population, Genome-Wide Association Study, Genotyping Techniques, Humans, Oligonucleotide Array Sequence Analysis, Phylogeography, Polymorphism, Single Nucleotide, Principal Component Analysis, Reproducibility of Results, Sample Size, Whites
Added February 4, 2016

A powerful association test of multiple genetic variants using a random-effects model.
Cheng KF, Lee JY, Zheng W, Li C
(2014) Stat Med 33: 1816-27
MeSH Terms: Breast Neoplasms, China, Computer Simulation, Female, Genetic Association Studies, Genetic Predisposition to Disease, Genetic Variation, Genotype, Humans, Models, Genetic, Receptor, Fibroblast Growth Factor, Type 2, Sample Size
Added March 20, 2014

Sample size calculation based on exact test for assessing differential expression analysis in RNA-seq data.
Li CI, Su PF, Shyr Y
(2013) BMC Bioinformatics 14: 357
MeSH Terms: Base Sequence, Computer Simulation, Gene Expression Regulation, Likelihood Functions, Models, Statistical, Poisson Distribution, RNA, Random Allocation, Research Design, Sample Size, Sequence Analysis, RNA, User-Computer Interface
Added March 10, 2014

No significant improvement in the rate of accurate ventricular catheter location using ultrasound-guided CSF shunt insertion: a prospective, controlled study by the Hydrocephalus Clinical Research Network.
Whitehead WE, Riva-Cambrin J, Wellons JC, Kulkarni AV, Holubkov R, Illner A, Oakes WJ, Luerssen TG, Walker ML, Drake JM, Kestle JR, Hydrocephalus Clinical Research Network
(2013) J Neurosurg Pediatr 12: 565-74
MeSH Terms: Adolescent, Child, Child, Preschool, Clinical Competence, Echoencephalography, Equipment Failure, Female, Foreign-Body Migration, Humans, Hydrocephalus, Infant, Infant, Newborn, Kaplan-Meier Estimate, Male, Prospective Studies, Sample Size, Time Factors, Treatment Outcome, Ultrasonography, Interventional, Ventriculoperitoneal Shunt
Added March 7, 2014

Sample size calculation for differential expression analysis of RNA-seq data under Poisson distribution.
Li CI, Su PF, Guo Y, Shyr Y
(2013) Int J Comput Biol Drug Des 6: 358-75
MeSH Terms: Humans, Kidney, Liver, Oligonucleotide Array Sequence Analysis, Poisson Distribution, Sample Size, Sequence Analysis, RNA
Added March 7, 2014