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Results: 1 to 2 of 2

Publication Record


General and persistent effects of high-intensity sweeteners on body weight gain and caloric compensation in rats.
Swithers SE, Baker CR, Davidson TL
(2009) Behav Neurosci 123: 772-80
MeSH Terms: Analysis of Variance, Animals, Body Weight, Diet, Energy Intake, Fabaceae, Feeding Behavior, Female, Glucose, Male, Random Allocation, Rats, Rats, Sprague-Dawley, Saccharin, Sweetening Agents, Thiazines, Time Factors, Weight Gain, Yogurt
Show Abstract · Added April 17, 2012
In an earlier work (S. E. Swithers & T. L. Davidson, 2008), rats provided with a fixed amount of a yogurt diet mixed with saccharin gained more weight and showed impaired caloric compensation relative to rats given the same amount of yogurt mixed with glucose. The present 4 experiments examined the generality of these findings and demonstrated that increased body weight gain was also demonstrated when animals consumed a yogurt diet sweetened with an alternative high-intensity sweetener (acesulfame potassium; AceK) as well as in animals given a saccharin-sweetened base diet (refried beans) that was calorically similar but nutritionally distinct from low-fat yogurt. These studies also extended earlier findings by showing that body weight differences persist after saccharin-sweetened diets are discontinued and following a shift to a diet sweetened with glucose. In addition, rats first exposed to a diet sweetened with glucose still gain additional weight when subsequently exposed to a saccharin-sweetened diet. The results of these experiments add support to the hypothesis that exposure to weak or nonpredictive relationships between sweet tastes and caloric consequences may lead to positive energy balance.
2009 APA, all rights reserved
0 Communities
1 Members
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19 MeSH Terms
Effect of sweeteners on energy uptake and its utilization by rats.
Gawecki J, Buchowski M, KurhaĊ„ska A, Urbanowicz M
(1978) Acta Physiol Pol 29: 481-7
MeSH Terms: Animals, Body Weight, Energy Metabolism, Female, Glucose, Glycine, Rats, Saccharin, Sweetening Agents
Show Abstract · Added July 31, 2015
The effect administration of saccharose, glucose and glycine in solutions of equivalent relative sweetness on the uptake and utilization of energy and on blood glucose level was studied in growing female Wistar rats. It was shown that the amount of saccharose and the remaining sweeteners added to drinks has an effect on the regulation of energy uptake from the food and on metabolic processes connected with the energy utilization.
0 Communities
1 Members
0 Resources
9 MeSH Terms