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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 6 of 6

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STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge.
Dulek DE, Newcomb DC, Toki S, Goliniewska K, Cephus J, Reiss S, Bates JT, Crowe JE, Boyd KL, Moore ML, Zhou W, Peebles RS
(2014) J Virol 88: 9655-72
MeSH Terms: Animals, CD8-Positive T-Lymphocytes, Disease Models, Animal, Female, Lung, Mice, Inbred BALB C, Mice, Knockout, Respiratory Syncytial Virus Infections, Respiratory Syncytial Viruses, STAT4 Transcription Factor, Th17 Cells, Th2 Cells
Added January 20, 2015
0 Communities
2 Members
0 Resources
12 MeSH Terms
Genetic markers associated with progression in early mycosis fungoides.
Johnson VE, Vonderheid EC, Hess AD, Eischen CM, McGirt LY
(2014) J Eur Acad Dermatol Venereol 28: 1431-5
MeSH Terms: Adult, Aged, Aged, 80 and over, Biomarkers, Tumor, Biopsy, CD3 Complex, Disease Progression, Down-Regulation, Female, Forkhead Transcription Factors, Humans, Interleukin-4, Male, Middle Aged, Mycosis Fungoides, RNA, Messenger, Retrospective Studies, STAT4 Transcription Factor, Skin, Skin Neoplasms, Up-Regulation
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
STAT4 and T-bet are required for the plasticity of IFN-γ expression across Th2 ontogeny and influence changes in Ifng promoter DNA methylation.
Williams CL, Schilling MM, Cho SH, Lee K, Wei M, Aditi , Boothby M
(2013) J Immunol 191: 678-87
MeSH Terms: Animals, Cell Differentiation, Cells, Cultured, CpG Islands, DNA Methylation, Immunologic Memory, Interferon-gamma, Interleukin-4, Lymphocyte Activation, Mice, Mice, Inbred BALB C, Mice, Knockout, Mice, Nude, Promoter Regions, Genetic, STAT4 Transcription Factor, T-Box Domain Proteins, Th1 Cells, Th2 Cells
Added March 7, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Transforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation.
Das J, Ren G, Zhang L, Roberts AI, Zhao X, Bothwell AL, Van Kaer L, Shi Y, Das G
(2009) J Exp Med 206: 2407-16
MeSH Terms: Animals, Cell Differentiation, Cytokines, Encephalomyelitis, Autoimmune, Experimental, GATA3 Transcription Factor, Interleukin-6, Lymphocyte Activation, Mice, Mice, Knockout, STAT4 Transcription Factor, STAT6 Transcription Factor, T-Box Domain Proteins, T-Lymphocytes, Helper-Inducer, Th1 Cells, Th2 Cells, Transforming Growth Factor beta
Added December 10, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
T helper type 1-specific Brg1 recruitment and remodeling of nucleosomes positioned at the IFN-gamma promoter are Stat4 dependent.
Zhang F, Boothby M
(2006) J Exp Med 203: 1493-505
MeSH Terms: Animals, CD4-Positive T-Lymphocytes, Cell Nucleus, Chromatin, DNA Helicases, Interferon-gamma, Mice, Mice, Inbred BALB C, Nuclear Proteins, Nucleosomes, Polymerase Chain Reaction, Promoter Regions, Genetic, STAT4 Transcription Factor, T-Lymphocytes, Th1 Cells, Transcription Factors
Added December 10, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
COX-2 inhibitors modulate IL-12 signaling through JAK-STAT pathway leading to Th1 response in experimental allergic encephalomyelitis.
Muthian G, Raikwar HP, Johnson C, Rajasingh J, Kalgutkar A, Marnett LJ, Bright JJ
(2006) J Clin Immunol 26: 73-85
MeSH Terms: Animals, Cell Proliferation, Cyclooxygenase 2 Inhibitors, Demyelinating Diseases, Encephalomyelitis, Autoimmune, Experimental, Inflammation, Interferon-gamma, Interleukin-12, Janus Kinase 2, Mice, Mice, Inbred C57BL, Multiple Sclerosis, Chronic Progressive, Multiple Sclerosis, Relapsing-Remitting, Phosphorylation, Protein-Tyrosine Kinases, Proto-Oncogene Proteins, STAT3 Transcription Factor, STAT4 Transcription Factor, Signal Transduction, Th1 Cells
Added March 5, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms