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Results: 1 to 10 of 15

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Cobicistat Versus Ritonavir: Similar Pharmacokinetic Enhancers But Some Important Differences.
Tseng A, Hughes CA, Wu J, Seet J, Phillips EJ
(2017) Ann Pharmacother 51: 1008-1022
MeSH Terms: Anti-HIV Agents, Atazanavir Sulfate, Cobicistat, Darunavir, Drug Interactions, HIV Infections, Humans, Quinolones, Ritonavir
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Phase I safety, pharmacokinetics, and pharmacogenetics study of the antituberculosis drug PA-824 with concomitant lopinavir-ritonavir, efavirenz, or rifampin.
Dooley KE, Luetkemeyer AF, Park JG, Allen R, Cramer Y, Murray S, Sutherland D, Aweeka F, Koletar SL, Marzan F, Bao J, Savic R, Haas DW, AIDS Clinical Trials Group A5306 Study Team
(2014) Antimicrob Agents Chemother 58: 5245-52
MeSH Terms: Adult, Alkynes, Antitubercular Agents, Antiviral Agents, Benzoxazines, Cyclopropanes, Drug Combinations, Drug Therapy, Combination, Female, Humans, Lopinavir, Male, Middle Aged, Nitroimidazoles, Pharmacogenetics, Rifampin, Ritonavir, Young Adult
Added March 13, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
Genomewide association study of atazanavir pharmacokinetics and hyperbilirubinemia in AIDS Clinical Trials Group protocol A5202.
Johnson DH, Venuto C, Ritchie MD, Morse GD, Daar ES, McLaren PJ, Haas DW
(2014) Pharmacogenet Genomics 24: 195-203
MeSH Terms: Acquired Immunodeficiency Syndrome, Adult, Antiretroviral Therapy, Highly Active, Atazanavir Sulfate, Bilirubin, Female, Genome-Wide Association Study, Glucuronosyltransferase, HIV Protease Inhibitors, Humans, Hyperbilirubinemia, Male, Middle Aged, Multivariate Analysis, Oligopeptides, Polymorphism, Single Nucleotide, Prospective Studies, Pyridines, Ritonavir
Added March 13, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Discordant associations between SLCO1B1 521T→C and plasma levels of ritonavir-boosted protease inhibitors in AIDS clinical trials group study A5146.
Zhang X, Tierney C, Albrecht M, Demeter LM, Morse G, DiFrancesco R, Dykes C, Jiang H, Haas DW
(2013) Ther Drug Monit 35: 209-16
MeSH Terms: Acquired Immunodeficiency Syndrome, Adult, Female, Genetic Association Studies, HIV Protease Inhibitors, Humans, Linkage Disequilibrium, Liver-Specific Organic Anion Transporter 1, Male, Middle Aged, Organic Anion Transporters, Ritonavir
Added March 13, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
Impact of UGT1A1 Gilbert variant on discontinuation of ritonavir-boosted atazanavir in AIDS Clinical Trials Group Study A5202.
Ribaudo HJ, Daar ES, Tierney C, Morse GD, Mollan K, Sax PE, Fischl MA, Collier AC, Haas DW, DS Clinical Trials Group
(2013) J Infect Dis 207: 420-5
MeSH Terms: Anti-HIV Agents, Antiretroviral Therapy, Highly Active, Atazanavir Sulfate, Bilirubin, Genetic Variation, Genotype, Glucuronosyltransferase, HIV Infections, HIV-1, Humans, Jaundice, Oligopeptides, Pyridines, Ritonavir
Added March 13, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Transient cardiac arrhythmias related to lopinavir/ritonavir in two patients with HIV infection.
Chaubey SK, Sinha AK, Phillips E, Russell DB, Falhammar H
(2009) Sex Health 6: 254-7
MeSH Terms: Adult, Anti-HIV Agents, Arrhythmias, Cardiac, Electrocardiography, HIV Infections, Humans, Lopinavir, Male, Middle Aged, Pyrimidinones, Ritonavir
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Metabolic outcomes in a randomized trial of nucleoside, nonnucleoside and protease inhibitor-sparing regimens for initial HIV treatment.
Haubrich RH, Riddler SA, DiRienzo AG, Komarow L, Powderly WG, Klingman K, Garren KW, Butcher DL, Rooney JF, Haas DW, Mellors JW, Havlir DV, AIDS Clinical Trials Group (ACTG) A5142 Study Team
(2009) AIDS 23: 1109-18
MeSH Terms: Absorptiometry, Photon, Adult, Alkynes, Benzoxazines, Cyclopropanes, Female, HIV Infections, HIV Protease Inhibitors, HIV-1, HIV-Associated Lipodystrophy Syndrome, Humans, Lipid Metabolism, Lopinavir, Male, Pyrimidinones, Ritonavir
Added March 13, 2015
0 Communities
1 Members
0 Resources
16 MeSH Terms
Hepatotoxicity and gastrointestinal intolerance when healthy volunteers taking rifampin add twice-daily atazanavir and ritonavir.
Haas DW, Koletar SL, Laughlin L, Kendall MA, Suckow C, Gerber JG, Zolopa AR, Bertz R, Child MJ, Hosey L, Alston-Smith B, Acosta EP, A5213 StudyTeam
(2009) J Acquir Immune Defic Syndr 50: 290-3
MeSH Terms: Adult, Antitubercular Agents, Atazanavir Sulfate, Female, Gastrointestinal Tract, HIV Protease Inhibitors, Humans, Liver, Male, Oligopeptides, Pyridines, Rifampin, Ritonavir
Added March 13, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Ritonavir, saquinavir, and efavirenz, but not nevirapine, inhibit bile acid transport in human and rat hepatocytes.
McRae MP, Lowe CM, Tian X, Bourdet DL, Ho RH, Leake BF, Kim RB, Brouwer KL, Kashuba AD
(2006) J Pharmacol Exp Ther 318: 1068-75
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 11, ATP-Binding Cassette Transporters, Adolescent, Adult, Aged, Aged, 80 and over, Alkynes, Animals, Anti-HIV Agents, Benzoxazines, Biological Transport, Cells, Cultured, Child, Cyclopropanes, Hepatocytes, Humans, Male, Middle Aged, Nevirapine, Organic Anion Transporters, Organic Anion Transporters, Sodium-Dependent, Oxazines, Rats, Ritonavir, Saquinavir, Symporters, Taurocholic Acid
Added March 5, 2014
2 Communities
2 Members
2 Resources
27 MeSH Terms
MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: an adult AIDS Clinical Trials Group study.
Haas DW, Wu H, Li H, Bosch RJ, Lederman MM, Kuritzkes D, Landay A, Connick E, Benson C, Wilkinson GR, Kessler H, Kim RB
(2003) J Acquir Immune Defic Syndr 34: 295-8
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Adult, Alleles, CD4 Lymphocyte Count, CD4-Positive T-Lymphocytes, Drug Therapy, Combination, Female, Genes, MDR, HIV Infections, HIV Protease Inhibitors, HIV-1, Humans, Lamivudine, Male, Middle Aged, Polymorphism, Single Nucleotide, RNA, Viral, Retrospective Studies, Ritonavir, Zidovudine
Added March 13, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms