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Results: 1 to 10 of 21

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Structural and functional analyses of the spliceosome requires a multi-disciplinary approach.
Ohi MD
(2017) Methods 125: 1-2
MeSH Terms: Animals, Humans, RNA Splicing, RNA, Messenger, Ribonucleoproteins, Small Nuclear, Spliceosomes
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Dyskerin, tRNA genes, and condensin tether pericentric chromatin to the spindle axis in mitosis.
Snider CE, Stephens AD, Kirkland JG, Hamdani O, Kamakaka RT, Bloom K
(2014) J Cell Biol 207: 189-99
MeSH Terms: Adenosine Triphosphatases, Centrosome, Chromatin, DNA-Binding Proteins, Hydro-Lyases, Kinetochores, Microtubule-Associated Proteins, Mitosis, Multiprotein Complexes, RNA, Transfer, Ribonucleoproteins, Small Nuclear, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Spindle Apparatus
Added January 25, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
Structure and functional implications of a complex containing a segment of U6 RNA bound by a domain of Prp24.
Martin-Tumasz S, Reiter NJ, Brow DA, Butcher SE
(2010) RNA 16: 792-804
MeSH Terms: Base Sequence, Binding Sites, Conserved Sequence, DNA Helicases, Models, Molecular, Molecular Sequence Data, Nucleic Acid Conformation, Protein Structure, Tertiary, RNA, Fungal, RNA, Small Nuclear, Ribonucleoproteins, Small Nuclear, Ribonucleoside Diphosphate Reductase, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins
Added January 28, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Structural characterization of the fission yeast U5.U2/U6 spliceosome complex.
Ohi MD, Ren L, Wall JS, Gould KL, Walz T
(2007) Proc Natl Acad Sci U S A 104: 3195-200
MeSH Terms: Cryoelectron Microscopy, Models, Molecular, Multiprotein Complexes, Protein Conformation, Protein Structure, Tertiary, RNA Splicing, Reverse Transcriptase Polymerase Chain Reaction, Ribonucleoproteins, Small Nuclear, Schizosaccharomyces, Spliceosomes
Added March 5, 2014
0 Communities
3 Members
0 Resources
10 MeSH Terms
Structure and interactions of the first three RNA recognition motifs of splicing factor prp24.
Bae E, Reiter NJ, Bingman CA, Kwan SS, Lee D, Phillips GN, Butcher SE, Brow DA
(2007) J Mol Biol 367: 1447-58
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Models, Molecular, Molecular Sequence Data, Mutation, Nucleic Acid Conformation, Protein Binding, Protein Structure, Secondary, RNA Splicing, RNA, Fungal, RNA, Small Nuclear, RNA-Binding Proteins, Ribonucleoproteins, Small Nuclear, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Sequence Homology, Amino Acid
Added January 28, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Resonance assignments for the two N-terminal RNA recognition motifs (RRM) of the S. cerevisiae pre-mRNA processing protein Prp24.
Reiter NJ, Lee D, Wang YX, Tonelli M, Bahrami A, Cornilescu CC, Butcher SE
(2006) J Biomol NMR 36 Suppl 1: 58
MeSH Terms: Amino Acids, Binding Sites, Nitrogen Isotopes, Nuclear Magnetic Resonance, Biomolecular, Peptide Fragments, Point Mutation, Ribonucleoproteins, Small Nuclear, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins
Added January 28, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
The splicing factor PSF is part of a large complex that assembles in the absence of pre-mRNA and contains all five snRNPs.
Peng R, Hawkins I, Link AJ, Patton JG
(2006) RNA Biol 3: 69-76
MeSH Terms: Alternative Splicing, Animals, Exons, HeLa Cells, Humans, Mass Spectrometry, PTB-Associated Splicing Factor, RNA Splicing, RNA, Messenger, RNA, Small Nuclear, RNA-Binding Proteins, Ribonucleoproteins, Small Nuclear, Saccharomyces cerevisiae, Spliceosomes, Transcription, Genetic
Added April 18, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms
Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast.
Wilkinson CR, Dittmar GA, Ohi MD, Uetz P, Jones N, Finley D
(2004) Curr Biol 14: 2283-8
MeSH Terms: Cell Cycle, Electrophoresis, Polyacrylamide Gel, Flow Cytometry, Genes, Essential, Microscopy, Fluorescence, Mutation, Oligonucleotides, Protein Transport, RNA Splicing, Reverse Transcriptase Polymerase Chain Reaction, Ribonucleoproteins, Small Nuclear, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Two-Hybrid System Techniques, Ubiquitin-Protein Ligase Complexes, Ubiquitins
Added March 5, 2014
0 Communities
2 Members
0 Resources
16 MeSH Terms
SNRPN methylation patterns in germ cell tumors as a reflection of primordial germ cell development.
Bussey KJ, Lawce HJ, Himoe E, Shu XO, Heerema NA, Perlman EJ, Olson SB, Magenis RE
(2001) Genes Chromosomes Cancer 32: 342-52
MeSH Terms: Adolescent, Adult, Autoantigens, Child, Child, Preschool, DNA Methylation, DNA, Neoplasm, Female, Genomic Imprinting, Germ Cells, Germinoma, Humans, Infant, Infant, Newborn, Male, Ribonucleoproteins, Small Nuclear, Tumor Cells, Cultured, snRNP Core Proteins
Added December 10, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms
Myb-related fission yeast cdc5p is a component of a 40S snRNP-containing complex and is essential for pre-mRNA splicing.
McDonald WH, Ohi R, Smelkova N, Frendewey D, Gould KL
(1999) Mol Cell Biol 19: 5352-62
MeSH Terms: Cell Cycle, Cell Cycle Proteins, Chromatography, Affinity, Fungal Proteins, Gene Expression Regulation, Fungal, Macromolecular Substances, Molecular Weight, Multiprotein Complexes, RNA Precursors, RNA Splicing, RNA, Fungal, RNA-Binding Proteins, Ribonucleoproteins, Small Nuclear, Saccharomyces cerevisiae Proteins, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Spliceosomes
Added March 5, 2014
0 Communities
3 Members
0 Resources
17 MeSH Terms