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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 7 of 7

Publication Record

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A Coordinated Attack: Rett Syndrome Therapeutic Development.
Gogliotti RG, Niswender CM
(2019) Trends Pharmacol Sci 40: 233-236
MeSH Terms: Animals, Drug Discovery, Drug Evaluation, Preclinical, Drug Repositioning, Female, Humans, Methyl-CpG-Binding Protein 2, Mutation, Research Design, Rett Syndrome
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Total RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M Muscarinic Receptor as a Novel Therapeutic Target.
Gogliotti RG, Fisher NM, Stansley BJ, Jones CK, Lindsley CW, Conn PJ, Niswender CM
(2018) J Pharmacol Exp Ther 365: 291-300
MeSH Terms: Animals, Autopsy, Cerebellum, Humans, Mice, Molecular Targeted Therapy, Motor Cortex, Receptor, Muscarinic M4, Rett Syndrome, Sequence Analysis, RNA
Added March 3, 2020
0 Communities
2 Members
0 Resources
MeSH Terms
mGlu potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome.
Gogliotti RG, Senter RK, Fisher NM, Adams J, Zamorano R, Walker AG, Blobaum AL, Engers DW, Hopkins CR, Daniels JS, Jones CK, Lindsley CW, Xiang Z, Conn PJ, Niswender CM
(2017) Sci Transl Med 9:
MeSH Terms: Animals, Apnea, Autopsy, CA1 Region, Hippocampal, Cognition, Disease Models, Animal, Dose-Response Relationship, Drug, Female, Humans, Long-Term Potentiation, Male, Memory, Methyl-CpG-Binding Protein 2, Mice, Motor Cortex, Neuronal Plasticity, Phenotype, Picolinic Acids, RNA, Messenger, Rats, Sprague-Dawley, Receptors, Metabotropic Glutamate, Respiration, Rett Syndrome, Social Behavior, Transcription, Genetic
Added March 3, 2020
0 Communities
2 Members
0 Resources
MeSH Terms
mGlu5 positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome.
Gogliotti RG, Senter RK, Rook JM, Ghoshal A, Zamorano R, Malosh C, Stauffer SR, Bridges TM, Bartolome JM, Daniels JS, Jones CK, Lindsley CW, Conn PJ, Niswender CM
(2016) Hum Mol Genet 25: 1990-2004
MeSH Terms: Adult, Allosteric Regulation, Animals, Autistic Disorder, Autopsy, Disease Models, Animal, Female, Gene Expression Regulation, Hippocampus, Humans, Male, Methyl-CpG-Binding Protein 2, Mice, Mice, Knockout, Motor Cortex, Neuronal Plasticity, Pyrazoles, Pyrimidinones, Receptor, Metabotropic Glutamate 5, Rett Syndrome, Seizures, Signal Transduction, Young Adult
Added April 6, 2017
0 Communities
4 Members
0 Resources
23 MeSH Terms
Genetic modifiers of neurological disease.
Kearney JA
(2011) Curr Opin Genet Dev 21: 349-53
MeSH Terms: Animals, Carrier Proteins, Charcot-Marie-Tooth Disease, Disease Models, Animal, Humans, Huntington Disease, Mice, Nervous System Diseases, Phenotype, RNA Splicing Factors, Rett Syndrome, Spinocerebellar Ataxias
Added May 27, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Bone mineral content and density in Rett syndrome and their contributing factors.
Jefferson AL, Woodhead HJ, Fyfe S, Briody J, Bebbington A, Strauss BJ, Jacoby P, Leonard H
(2011) Pediatr Res 69: 293-8
MeSH Terms: Absorptiometry, Photon, Adult, Australia, Body Composition, Body Height, Bone Density, Child, Databases, Factual, Female, Humans, Rett Syndrome, Surveys and Questionnaires
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2.
Young JI, Hong EP, Castle JC, Crespo-Barreto J, Bowman AB, Rose MF, Kang D, Richman R, Johnson JM, Berget S, Zoghbi HY
(2005) Proc Natl Acad Sci U S A 102: 17551-8
MeSH Terms: Animals, Cell Line, Tumor, DNA Methylation, Exons, Gene Expression Profiling, Genes, Reporter, Humans, Methyl-CpG-Binding Protein 2, Mice, Models, Genetic, Protein Binding, RNA, RNA Splicing, Rett Syndrome, Transcription, Genetic
Added June 9, 2010
1 Communities
1 Members
0 Resources
15 MeSH Terms