Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells.
Brábek J, Constancio SS, Siesser PF, Shin NY, Pozzi A, Hanks SK
(2005) Mol Cancer Res 3
: 307-15MeSH Terms: Animals, Binding Sites, Cell Line, Transformed, Cell Movement, Cells, Cultured, Collagen, Cytoskeletal Proteins, Drug Combinations, Enzyme Activation, Focal Adhesion Kinase 1, Focal Adhesion Protein-Tyrosine Kinases, Genes, src, Injections, Subcutaneous, Laminin, Lung Neoplasms, Matrix Metalloproteinase 2, Mice, Mice, Nude, Neoplasm Invasiveness, Neoplasm Transplantation, Oncogene Protein v-crk, Paxillin, Phosphoproteins, Phosphorylation, Protein-Tyrosine Kinases, Proteoglycans, Retroviridae Proteins, Oncogenic, Tyrosine, src Homology DomainsAdded February 24, 2014
29 MeSH Terms
Crk-associated substrate p130(Cas) interacts with nephrocystin and both proteins localize to cell-cell contacts of polarized epithelial cells.
Donaldson JC, Dempsey PJ, Reddy S, Bouton AH, Coffey RJ, Hanks SK
(2000) Exp Cell Res 256
: 168-78MeSH Terms: Adaptor Proteins, Signal Transducing, Amino Acid Sequence, Animals, Cell Line, Cell Polarity, Cell Transformation, Neoplastic, Crk-Associated Substrate Protein, Cytoskeletal Proteins, Dogs, Epithelial Cells, Genes, src, Humans, Intercellular Junctions, Kidney, Membrane Proteins, Mice, Molecular Sequence Data, Oncogene Protein v-crk, Phosphoproteins, Proteins, Recombinant Proteins, Retinoblastoma Protein, Retinoblastoma-Like Protein p130, Retroviridae Proteins, Oncogenic, Reverse Transcriptase Polymerase Chain Reaction, Sequence Alignment, Sequence Homology, Amino Acid, Transcription, Genetic, Transfection, src Homology DomainsAdded March 27, 2014
30 MeSH Terms
Prostaglandin A2 blocks the activation of G1 phase cyclin-dependent kinase without altering mitogen-activated protein kinase stimulation.
Hitomi M, Shu J, Strom D, Hiebert SW, Harter ML, Stacey DW
(1996) J Biol Chem 271
: 9376-83MeSH Terms: 3T3 Cells, Animals, Calcium-Calmodulin-Dependent Protein Kinases, Cell Cycle, Cell Transformation, Neoplastic, Cyclin-Dependent Kinases, Enzyme Activation, G1 Phase, G2 Phase, Kinetics, Mice, Microinjections, Mitosis, Oncogene Proteins v-raf, Oncogenes, Phosphorylation, Prostaglandins A, Retinoblastoma Protein, Retroviridae Proteins, Oncogenic, Time Factors, ras ProteinsAdded June 10, 2010
21 MeSH Terms
Activation of hepatic proliferation-associated transcription factors by lipopolysaccharide.
Beauchamp RD, Papaconstantinou J, Henderson AM, Sheng HM, Townsend CM, Thompson JC
(1994) Surgery 116
: 367-76; discussion 376-7MeSH Terms: Animals, Base Sequence, DNA-Binding Proteins, Early Growth Response Protein 1, Genes, Immediate-Early, Immediate-Early Proteins, Lipopolysaccharides, Liver, Male, Mice, Mice, Inbred BALB C, Molecular Sequence Data, Proto-Oncogene Proteins c-jun, RNA, Messenger, Retroviridae Proteins, Oncogenic, Transcription FactorsAdded May 3, 2013
16 MeSH Terms
Melanoma growth stimulatory activity signaling through the class II interleukin-8 receptor enhances the tyrosine phosphorylation of Crk-associated substrate, p130, and a 70-kilodalton protein.
Schraw W, Richmond A
(1995) Biochemistry 34
: 13760-7MeSH Terms: Antigens, CD, Blotting, Western, Cell Line, Cell Membrane, Chemokine CXCL1, Chemokines, CXC, Chemotactic Factors, Crk-Associated Substrate Protein, Cytosol, Growth Substances, Humans, Intercellular Signaling Peptides and Proteins, Melanoma, Molecular Weight, Neoplasm Proteins, Oncogene Protein v-crk, Phosphoproteins, Phosphorylation, Phosphotransferases, Placenta, Proteins, Receptors, Interleukin, Receptors, Interleukin-8A, Retinoblastoma-Like Protein p130, Retroviridae Proteins, Oncogenic, Serine, Transfection, TyrosineAdded May 30, 2013
28 MeSH Terms
Cell surface expression and orientation in membranes of the 44-amino-acid SH protein of simian virus 5.
Hiebert SW, Richardson CD, Lamb RA
(1988) J Virol 62
: 2347-57MeSH Terms: Amino Acid Sequence, Animals, Antibodies, Viral, Capsid, Cell Line, Chlorocebus aethiops, Fibroblasts, Kidney, Membrane Proteins, Molecular Sequence Data, Respirovirus, Retroviridae Proteins, OncogenicAdded June 10, 2010
12 MeSH Terms
Radiosensitivity of small-cell lung cancer xenografts compared with activity of c-myc, N-myc, L-myc, c-raf-1 and K-ras proto-oncogenes.
Rygaard K, Slebos RJ, Spang-Thomsen M
(1991) Int J Cancer 49
: 279-84MeSH Terms: Animals, Carcinoma, Small Cell, Gene Expression Regulation, Neoplastic, Genes, myc, Genes, ras, Lung Neoplasms, Mice, Mice, Nude, Neoplasm Transplantation, Oncogene Proteins v-raf, RNA, Messenger, RNA, Neoplasm, Radiation Tolerance, Retroviridae Proteins, OncogenicAdded March 5, 2014
14 MeSH Terms