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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 6 of 6

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A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases.
Benetti R, Gonzalo S, Jaco I, Muñoz P, Gonzalez S, Schoeftner S, Murchison E, Andl T, Chen T, Klatt P, Li E, Serrano M, Millar S, Hannon G, Blasco MA
(2008) Nat Struct Mol Biol 15: 268-79
MeSH Terms: Animals, Chromobox Protein Homolog 5, Chromosomal Proteins, Non-Histone, DEAD-box RNA Helicases, DNA (Cytosine-5-)-Methyltransferase 1, DNA (Cytosine-5-)-Methyltransferases, DNA Methylation, Endoribonucleases, Histones, Mice, MicroRNAs, Models, Biological, Recombination, Genetic, Retinoblastoma-Like Protein p130, Ribonuclease III, Telomerase, Telomere
Added January 30, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Tumors initiated by constitutive Cdk2 activation exhibit transforming growth factor beta resistance and acquire paracrine mitogenic stimulation during progression.
Corsino P, Davis B, Law M, Chytil A, Forrester E, Nørgaard P, Teoh N, Law B
(2007) Cancer Res 67: 3135-44
MeSH Terms: Animals, Cyclin D1, Cyclin-Dependent Kinase 2, Disease Progression, Enzyme Activation, Female, Fibroblasts, Hepatocyte Growth Factor, Hyperplasia, Mammary Glands, Animal, Mammary Neoplasms, Experimental, Mammary Tumor Virus, Mouse, Mice, Mice, Transgenic, Promoter Regions, Genetic, Recombinant Fusion Proteins, Retinoblastoma Protein, Retinoblastoma-Like Protein p130, Transforming Growth Factor beta
Added August 13, 2010
1 Communities
0 Members
0 Resources
19 MeSH Terms
A dynamic equilibrium between CDKs and PP2A modulates phosphorylation of pRB, p107 and p130.
Garriga J, Jayaraman AL, Limón A, Jayadeva G, Sotillo E, Truongcao M, Patsialou A, Wadzinski BE, Graña X
(2004) Cell Cycle 3: 1320-30
MeSH Terms: Antigens, Viral, Tumor, Binding Sites, Cell Cycle, Cell Line, Tumor, Cyclin D1, Cyclin-Dependent Kinases, Humans, Phosphoprotein Phosphatases, Phosphorylation, Protein Binding, Protein Biosynthesis, Retinoblastoma Protein, Retinoblastoma-Like Protein p107, Retinoblastoma-Like Protein p130
Added December 10, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.
Law BK, Chytil A, Dumont N, Hamilton EG, Waltner-Law ME, Aakre ME, Covington C, Moses HL
(2002) Mol Cell Biol 22: 8184-98
MeSH Terms: Animals, Antibiotics, Antineoplastic, CDC2-CDC28 Kinases, Carcinoma, Cell Cycle Proteins, Cell Division, Cell Line, Cell Transformation, Neoplastic, Cyclin-Dependent Kinase 2, Cyclin-Dependent Kinase Inhibitor p21, Cyclin-Dependent Kinase Inhibitor p27, Cyclin-Dependent Kinases, Cyclins, DNA-Binding Proteins, E2F4 Transcription Factor, Enzyme Inhibitors, Epithelial Cells, Genes, Reporter, Growth Inhibitors, Humans, Nuclear Proteins, Phosphoproteins, Protein Binding, Protein Serine-Threonine Kinases, Proteins, Retinoblastoma Protein, Retinoblastoma-Like Protein p107, Retinoblastoma-Like Protein p130, Signal Transduction, Sirolimus, Tacrolimus Binding Proteins, Transcription Factors, Transforming Growth Factor beta, Tumor Suppressor Proteins
Added February 17, 2014
0 Communities
1 Members
0 Resources
34 MeSH Terms
Crk-associated substrate p130(Cas) interacts with nephrocystin and both proteins localize to cell-cell contacts of polarized epithelial cells.
Donaldson JC, Dempsey PJ, Reddy S, Bouton AH, Coffey RJ, Hanks SK
(2000) Exp Cell Res 256: 168-78
MeSH Terms: Adaptor Proteins, Signal Transducing, Amino Acid Sequence, Animals, Cell Line, Cell Polarity, Cell Transformation, Neoplastic, Crk-Associated Substrate Protein, Cytoskeletal Proteins, Dogs, Epithelial Cells, Genes, src, Humans, Intercellular Junctions, Kidney, Membrane Proteins, Mice, Molecular Sequence Data, Oncogene Protein v-crk, Phosphoproteins, Proteins, Recombinant Proteins, Retinoblastoma Protein, Retinoblastoma-Like Protein p130, Retroviridae Proteins, Oncogenic, Reverse Transcriptase Polymerase Chain Reaction, Sequence Alignment, Sequence Homology, Amino Acid, Transcription, Genetic, Transfection, src Homology Domains
Added March 27, 2014
1 Communities
1 Members
0 Resources
30 MeSH Terms
Melanoma growth stimulatory activity signaling through the class II interleukin-8 receptor enhances the tyrosine phosphorylation of Crk-associated substrate, p130, and a 70-kilodalton protein.
Schraw W, Richmond A
(1995) Biochemistry 34: 13760-7
MeSH Terms: Antigens, CD, Blotting, Western, Cell Line, Cell Membrane, Chemokine CXCL1, Chemokines, CXC, Chemotactic Factors, Crk-Associated Substrate Protein, Cytosol, Growth Substances, Humans, Intercellular Signaling Peptides and Proteins, Melanoma, Molecular Weight, Neoplasm Proteins, Oncogene Protein v-crk, Phosphoproteins, Phosphorylation, Phosphotransferases, Placenta, Proteins, Receptors, Interleukin, Receptors, Interleukin-8A, Retinoblastoma-Like Protein p130, Retroviridae Proteins, Oncogenic, Serine, Transfection, Tyrosine
Added May 30, 2013
2 Communities
1 Members
0 Resources
28 MeSH Terms