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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 43

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A key interaction with RPA orients XPA in NER complexes.
Topolska-Woś AM, Sugitani N, Cordoba JJ, Le Meur KV, Le Meur RA, Kim HS, Yeo JE, Rosenberg D, Hammel M, Schärer OD, Chazin WJ
(2020) Nucleic Acids Res 48: 2173-2188
MeSH Terms: DNA, DNA Damage, DNA Repair, DNA, Single-Stranded, DNA-Binding Proteins, Humans, Magnetic Resonance Spectroscopy, Models, Molecular, Protein Binding, Replication Protein A, Xeroderma Pigmentosum Group A Protein
Added March 11, 2020
0 Communities
1 Members
0 Resources
11 MeSH Terms
Analysis of Functional Dynamics of Modular Multidomain Proteins by SAXS and NMR.
Thompson MK, Ehlinger AC, Chazin WJ
(2017) Methods Enzymol 592: 49-76
MeSH Terms: DNA Primase, Humans, Multiprotein Complexes, Nuclear Magnetic Resonance, Biomolecular, Protein Conformation, Protein Domains, Replication Protein A, Scattering, Small Angle, X-Ray Diffraction
Added March 24, 2018
0 Communities
1 Members
0 Resources
9 MeSH Terms
Molecular basis for PrimPol recruitment to replication forks by RPA.
Guilliam TA, Brissett NC, Ehlinger A, Keen BA, Kolesar P, Taylor EM, Bailey LJ, Lindsay HD, Chazin WJ, Doherty AJ
(2017) Nat Commun 8: 15222
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Animals, Chickens, Chromatin, Crystallography, X-Ray, DNA Primase, DNA Replication, DNA-Directed DNA Polymerase, HEK293 Cells, Humans, Models, Biological, Multifunctional Enzymes, Protein Binding, Protein Domains, Replication Protein A, Xenopus
Added March 24, 2018
0 Communities
1 Members
0 Resources
17 MeSH Terms
Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A.
Patrone JD, Pelz NF, Bates BS, Souza-Fagundes EM, Vangamudi B, Camper DV, Kuznetsov AG, Browning CF, Feldkamp MD, Frank AO, Gilston BA, Olejniczak ET, Rossanese OW, Waterson AG, Chazin WJ, Fesik SW
(2016) ChemMedChem 11: 893-9
MeSH Terms: Anisotropy, Dose-Response Relationship, Drug, Fluorescence Polarization, High-Throughput Screening Assays, Models, Molecular, Molecular Structure, Replication Protein A, Structure-Activity Relationship, ortho-Aminobenzoates
Added February 5, 2016
0 Communities
1 Members
0 Resources
9 MeSH Terms
Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry.
Zhao W, Vaithiyalingam S, San Filippo J, Maranon DG, Jimenez-Sainz J, Fontenay GV, Kwon Y, Leung SG, Lu L, Jensen RB, Chazin WJ, Wiese C, Sung P
(2015) Mol Cell 59: 176-87
MeSH Terms: Amino Acid Substitution, BRCA2 Protein, Breast Neoplasms, Cell Line, Female, HeLa Cells, Homologous Recombination, Humans, Models, Biological, Molecular Mimicry, Mutagenesis, Site-Directed, Nuclear Magnetic Resonance, Biomolecular, Proteasome Endopeptidase Complex, Protein Subunits, Rad51 Recombinase, Recombinant Proteins, Replication Protein A
Added February 5, 2016
1 Communities
2 Members
0 Resources
17 MeSH Terms
Functional dynamics in replication protein A DNA binding and protein recruitment domains.
Brosey CA, Soss SE, Brooks S, Yan C, Ivanov I, Dorai K, Chazin WJ
(2015) Structure 23: 1028-38
MeSH Terms: DNA, Diffusion Tensor Imaging, Gene Components, Models, Molecular, Molecular Dynamics Simulation, Nuclear Magnetic Resonance, Biomolecular, Protein Binding, Protein Conformation, Protein Structure, Tertiary, Replication Protein A
Added February 5, 2016
0 Communities
1 Members
0 Resources
10 MeSH Terms
Mechanochemical regulations of RPA's binding to ssDNA.
Chen J, Le S, Basu A, Chazin WJ, Yan J
(2015) Sci Rep 5: 9296
MeSH Terms: Biomechanical Phenomena, DNA Replication, DNA, Single-Stranded, Kinetics, Models, Biological, Protein Binding, Replication Protein A, Sodium Chloride
Added March 11, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Simian virus Large T antigen interacts with the N-terminal domain of the 70 kD subunit of Replication Protein A in the same mode as multiple DNA damage response factors.
Ning B, Feldkamp MD, Cortez D, Chazin WJ, Friedman KL, Fanning E
(2015) PLoS One 10: e0116093
MeSH Terms: Antigens, Viral, Tumor, DNA Helicases, DNA Replication, DNA, Viral, Replication Protein A, Simian virus 40, Virus Replication
Added February 4, 2016
1 Communities
4 Members
0 Resources
7 MeSH Terms
High-affinity DNA-binding domains of replication protein A (RPA) direct SMARCAL1-dependent replication fork remodeling.
Bhat KP, Bétous R, Cortez D
(2015) J Biol Chem 290: 4110-7
MeSH Terms: Amino Acid Motifs, Bone Neoplasms, DNA Damage, DNA Helicases, DNA Replication, DNA, Single-Stranded, Electrophoretic Mobility Shift Assay, Humans, Osteosarcoma, Protein Binding, Replication Protein A, Substrate Specificity, Tumor Cells, Cultured
Added January 20, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins.
Guilliam TA, Jozwiakowski SK, Ehlinger A, Barnes RP, Rudd SG, Bailey LJ, Skehel JM, Eckert KA, Chazin WJ, Doherty AJ
(2015) Nucleic Acids Res 43: 1056-68
MeSH Terms: DNA Primase, DNA Primers, DNA Replication, DNA-Binding Proteins, DNA-Directed DNA Polymerase, Humans, Mitochondrial Proteins, Multifunctional Enzymes, Mutagenesis, Proliferating Cell Nuclear Antigen, Protein Interaction Domains and Motifs, Replication Protein A
Added January 20, 2015
1 Communities
3 Members
0 Resources
12 MeSH Terms