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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 832

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infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease.
Mileto SJ, Jardé T, Childress KO, Jensen JL, Rogers AP, Kerr G, Hutton ML, Sheedlo MJ, Bloch SC, Shupe JA, Horvay K, Flores T, Engel R, Wilkins S, McMurrick PJ, Lacy DB, Abud HE, Lyras D
(2020) Proc Natl Acad Sci U S A 117: 8064-8073
MeSH Terms: Animals, Bacterial Proteins, Bacterial Toxins, Cells, Cultured, Clostridioides difficile, Clostridium Infections, Colon, Disease Models, Animal, Female, Frizzled Receptors, Humans, Intestinal Mucosa, Mice, Organoids, Primary Cell Culture, Recombinant Proteins, Stem Cells
Added March 24, 2020
0 Communities
1 Members
0 Resources
17 MeSH Terms
E. coli production process yields stable dengue 1 virus-sized particles (VSPs).
Hirsch J, Faber BW, Crowe JE, Verstrepen B, Cornelissen G
(2020) Vaccine 38: 3305-3312
MeSH Terms: Animals, Antibodies, Neutralizing, Antibodies, Viral, Dengue Vaccines, Escherichia coli, Rabbits, Recombinant Proteins, Vaccines, Virus-Like Particle, Viral Envelope Proteins
Added March 31, 2020
0 Communities
1 Members
0 Resources
9 MeSH Terms
Probing biophysical sequence constraints within the transmembrane domains of rhodopsin by deep mutational scanning.
Penn WD, McKee AG, Kuntz CP, Woods H, Nash V, Gruenhagen TC, Roushar FJ, Chandak M, Hemmerich C, Rusch DB, Meiler J, Schlebach JP
(2020) Sci Adv 6: eaay7505
MeSH Terms: Cell Membrane, Gene Expression, HEK293 Cells, Humans, Hydrophobic and Hydrophilic Interactions, Lipid Bilayers, Models, Molecular, Mutation, Protein Domains, Protein Folding, Protein Structure, Secondary, Recombinant Proteins, Rhodopsin, Solubility, Thermodynamics
Added March 21, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Structural analysis of lecithin:cholesterol acyltransferase bound to high density lipoprotein particles.
Manthei KA, Patra D, Wilson CJ, Fawaz MV, Piersimoni L, Shenkar JC, Yuan W, Andrews PC, Engen JR, Schwendeman A, Ohi MD, Tesmer JJG
(2020) Commun Biol 3: 28
MeSH Terms: Binding Sites, Catalytic Domain, Lipoproteins, HDL, Lysine, Mass Spectrometry, Models, Molecular, Multiprotein Complexes, Phosphatidylcholine-Sterol O-Acyltransferase, Protein Binding, Protein Conformation, Recombinant Proteins, Structure-Activity Relationship
Added March 3, 2020
0 Communities
1 Members
0 Resources
12 MeSH Terms
Two-week administration of engineered Escherichia coli establishes persistent resistance to diet-induced obesity even without antibiotic pre-treatment.
Dosoky NS, Chen Z, Guo Y, McMillan C, Flynn CR, Davies SS
(2019) Appl Microbiol Biotechnol 103: 6711-6723
MeSH Terms: Acyltransferases, Animals, Anti-Bacterial Agents, Anti-Obesity Agents, Arabidopsis, Diet, High-Fat, Disease Models, Animal, Escherichia coli, Humans, Metabolic Engineering, Mice, Obesity, Phosphatidylethanolamines, Plant Proteins, Probiotics, Recombinant Proteins, Treatment Outcome
Added July 17, 2019
1 Communities
2 Members
0 Resources
17 MeSH Terms
Crystal structure of the SH3 domain of human Lyn non-receptor tyrosine kinase.
Berndt S, Gurevich VV, Iverson TM
(2019) PLoS One 14: e0215140
MeSH Terms: Crystallography, X-Ray, Humans, Mutation, Neoplasms, Protein Structure, Tertiary, Recombinant Proteins, src Homology Domains, src-Family Kinases
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains.
Turner HL, Pallesen J, Lang S, Bangaru S, Urata S, Li S, Cottrell CA, Bowman CA, Crowe JE, Wilson IA, Ward AB
(2019) PLoS Biol 17: e3000139
MeSH Terms: Amino Acid Sequence, Animals, Antibodies, Neutralizing, Antibody Specificity, Baculoviridae, Binding Sites, Cloning, Molecular, Cryoelectron Microscopy, Gene Expression, Hemagglutinin Glycoproteins, Influenza Virus, Hydrogen Bonding, Immunoglobulin Fab Fragments, Influenza A virus, Molecular Docking Simulation, Protein Binding, Protein Conformation, alpha-Helical, Protein Conformation, beta-Strand, Protein Interaction Domains and Motifs, Recombinant Proteins, Sequence Alignment, Sequence Homology, Amino Acid, Sf9 Cells, Spodoptera
Added March 31, 2019
0 Communities
1 Members
0 Resources
23 MeSH Terms
In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model.
Patel A, Park DH, Davis CW, Smith TRF, Leung A, Tierney K, Bryan A, Davidson E, Yu X, Racine T, Reed C, Gorman ME, Wise MC, Elliott STC, Esquivel R, Yan J, Chen J, Muthumani K, Doranz BJ, Saphire EO, Crowe JE, Broderick KE, Kobinger GP, He S, Qiu X, Kobasa D, Humeau L, Sardesai NY, Ahmed R, Weiner DB
(2018) Cell Rep 25: 1982-1993.e4
MeSH Terms: Animals, Antibodies, Monoclonal, DNA, Disease Models, Animal, Ebolavirus, Epitope Mapping, Epitopes, Female, Glycoproteins, HEK293 Cells, Hemorrhagic Fever, Ebola, Humans, Mice, Inbred BALB C, Muscles, Mutagenesis, Recombinant Proteins
Added March 31, 2019
0 Communities
1 Members
0 Resources
16 MeSH Terms
Localized low-dose rhBMP-2 is effective at promoting bone regeneration in mandibular segmental defects.
Carlisle P, Guda T, Silliman DT, Burdette AJ, Talley AD, Alvarez R, Tucker D, Hale RG, Guelcher SA, BrownBaer PR
(2019) J Biomed Mater Res B Appl Biomater 107: 1491-1503
MeSH Terms: Animals, Bone Morphogenetic Protein 2, Bone Regeneration, Calcium Phosphates, Drug Delivery Systems, Durapatite, Humans, Mandible, Mandibular Injuries, Recombinant Proteins, Swine, Swine, Miniature, Tomography, X-Ray Computed
Added March 20, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
Injectable, compression-resistant polymer/ceramic composite bone grafts promote lateral ridge augmentation without protective mesh in a canine model.
Talley AD, Boller LA, Kalpakci KN, Shimko DA, Cochran DL, Guelcher SA
(2018) Clin Oral Implants Res 29: 592-602
MeSH Terms: Alveolar Process, Alveolar Ridge Augmentation, Animals, Bone Morphogenetic Protein 2, Bone Transplantation, Ceramics, Dental Materials, Dogs, Male, Polymers, Rabbits, Recombinant Proteins, X-Ray Microtomography
Added March 20, 2020
0 Communities
1 Members
0 Resources
MeSH Terms