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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 47

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Predicting susceptibility to SARS-CoV-2 infection based on structural differences in ACE2 across species.
Alexander MR, Schoeder CT, Brown JA, Smart CD, Moth C, Wikswo JP, Capra JA, Meiler J, Chen W, Madhur MS
(2020) FASEB J 34: 15946-15960
MeSH Terms: Amino Acid Sequence, Angiotensin-Converting Enzyme 2, Animals, COVID-19, Camelus, Genetic Predisposition to Disease, Glycosylation, Horses, Humans, Models, Molecular, Phylogeny, Protein Binding, Protein Structure, Tertiary, Receptors, Virus, SARS-CoV-2, Sequence Alignment, Species Specificity
Added September 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Structural and Functional Features of the Reovirus σ1 Tail.
Dietrich MH, Ogden KM, Long JM, Ebenhoch R, Thor A, Dermody TS, Stehle T
(2018) J Virol 92:
MeSH Terms: Amino Acid Sequence, Capsid Proteins, Cells, Cultured, Crystallography, X-Ray, Protein Binding, Protein Conformation, Receptors, Virus, Reoviridae, Reoviridae Infections, Sequence Homology, Virus Attachment, Virus Internalization, Virus Replication
Added April 3, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.
King LB, Fusco ML, Flyak AI, Ilinykh PA, Huang K, Gunn B, Kirchdoerfer RN, Hastie KM, Sangha AK, Meiler J, Alter G, Bukreyev A, Crowe JE, Saphire EO
(2018) Cell Host Microbe 23: 101-109.e4
MeSH Terms: Agrobacterium tumefaciens, Animals, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Binding Sites, Carrier Proteins, Cell Line, Chlorocebus aethiops, Crystallography, X-Ray, Drosophila melanogaster, Humans, Intracellular Signaling Peptides and Proteins, Marburgvirus, Membrane Glycoproteins, Receptors, Virus, Tobacco, Vero Cells, Viral Envelope Proteins, Viral Fusion Proteins, Virus Attachment
Added March 17, 2018
0 Communities
1 Members
0 Resources
21 MeSH Terms
A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses.
Wec AZ, Nyakatura EK, Herbert AS, Howell KA, Holtsberg FW, Bakken RR, Mittler E, Christin JR, Shulenin S, Jangra RK, Bharrhan S, Kuehne AI, Bornholdt ZA, Flyak AI, Saphire EO, Crowe JE, Aman MJ, Dye JM, Lai JR, Chandran K
(2016) Science 354: 350-354
MeSH Terms: Animals, Antibodies, Bispecific, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Binding Sites, Carrier Proteins, Cell Line, Tumor, Ebolavirus, Endosomes, Hemorrhagic Fever, Ebola, Humans, Immunotherapy, Intracellular Signaling Peptides and Proteins, Membrane Glycoproteins, Mice, Mice, Inbred BALB C, Receptors, Virus, Viral Envelope Proteins, Virus Internalization
Added April 13, 2017
0 Communities
1 Members
0 Resources
20 MeSH Terms
Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies.
Bornholdt ZA, Ndungo E, Fusco ML, Bale S, Flyak AI, Crowe JE, Chandran K, Saphire EO
(2016) mBio 7: e02154-15
MeSH Terms: Antibodies, Neutralizing, Antibodies, Viral, Carrier Proteins, Cell Line, Crystallography, X-Ray, Ebolavirus, Hemorrhagic Fever, Ebola, Humans, Hydrophobic and Hydrophilic Interactions, Intracellular Signaling Peptides and Proteins, Membrane Glycoproteins, Mutagenesis, Mutation, Protein Binding, Receptors, Virus, Viral Envelope Proteins, Virus Internalization
Added May 4, 2016
0 Communities
1 Members
0 Resources
17 MeSH Terms
KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation.
Brooks CR, Yeung MY, Brooks YS, Chen H, Ichimura T, Henderson JM, Bonventre JV
(2015) EMBO J 34: 2441-64
MeSH Terms: Antigen Presentation, Apoptosis, Autophagy-Related Protein 5, Autophagy-Related Protein-1 Homolog, CD4-Positive T-Lymphocytes, Cell Proliferation, HEK293 Cells, Hepatitis A Virus Cellular Receptor 1, Humans, Intracellular Signaling Peptides and Proteins, Lipoylation, Membrane Glycoproteins, Microtubule-Associated Proteins, Phagocytosis, Protein-Serine-Threonine Kinases, Reactive Oxygen Species, Receptors, Virus
Added September 12, 2016
1 Communities
1 Members
0 Resources
17 MeSH Terms
Structure of Serotype 1 Reovirus Attachment Protein σ1 in Complex with Junctional Adhesion Molecule A Reveals a Conserved Serotype-Independent Binding Epitope.
Stettner E, Dietrich MH, Reiss K, Dermody TS, Stehle T
(2015) J Virol 89: 6136-40
MeSH Terms: Amino Acid Sequence, Binding Sites, Capsid Proteins, Crystallography, X-Ray, Junctional Adhesion Molecule A, Models, Molecular, Molecular Sequence Data, Protein Binding, Protein Conformation, Receptors, Virus, Sequence Homology
Added February 4, 2016
0 Communities
1 Members
0 Resources
11 MeSH Terms
Glycan engagement dictates hydrocephalus induction by serotype 1 reovirus.
Stencel-Baerenwald J, Reiss K, Blaum BS, Colvin D, Li XN, Abel T, Boyd K, Stehle T, Dermody TS
(2015) mBio 6: e02356
MeSH Terms: Animals, Animals, Newborn, Cells, Cultured, Disease Models, Animal, G(M2) Ganglioside, Hydrocephalus, Mice, Receptors, Virus, Reoviridae, Reoviridae Infections, Serogroup, Virus Attachment
Added February 4, 2016
0 Communities
1 Members
0 Resources
12 MeSH Terms
Furosemide Stress Test and Biomarkers for the Prediction of AKI Severity.
Koyner JL, Davison DL, Brasha-Mitchell E, Chalikonda DM, Arthur JM, Shaw AD, Tumlin JA, Trevino SA, Bennett MR, Kimmel PL, Seneff MG, Chawla LS
(2015) J Am Soc Nephrol 26: 2023-31
MeSH Terms: Acute Kidney Injury, Acute-Phase Proteins, Aged, Albuminuria, Biomarkers, Creatinine, Disease Progression, Diuretics, Female, Furosemide, Hepatitis A Virus Cellular Receptor 1, Humans, Insulin-Like Growth Factor Binding Proteins, Interleukin-18, Lipocalin-2, Lipocalins, Male, Membrane Glycoproteins, Middle Aged, Proto-Oncogene Proteins, Receptors, Virus, Severity of Illness Index, Sodium, Tissue Inhibitor of Metalloproteinase-2, Uromodulin
Added October 20, 2015
0 Communities
1 Members
0 Resources
25 MeSH Terms
Role of type I interferon signaling in human metapneumovirus pathogenesis and control of viral replication.
Hastings AK, Erickson JJ, Schuster JE, Boyd KL, Tollefson SJ, Johnson M, Gilchuk P, Joyce S, Williams JV
(2015) J Virol 89: 4405-20
MeSH Terms: Analysis of Variance, Animals, Antigen-Presenting Cells, CD8-Positive T-Lymphocytes, Flow Cytometry, Gene Expression Regulation, Hepatitis A Virus Cellular Receptor 2, Humans, Interferon Type I, Metapneumovirus, Mice, Mice, Inbred C57BL, Mice, Knockout, Oximetry, Paramyxoviridae Infections, Real-Time Polymerase Chain Reaction, Receptors, Virus, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, Virus Replication
Added October 2, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms