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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 63

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Apoptosis signal-regulating kinase 1 activation by Nox1-derived oxidants is required for TNFα receptor endocytosis.
Choi H, Stark RJ, Raja BS, Dikalova A, Lamb FS
(2019) Am J Physiol Heart Circ Physiol 316: H1528-H1537
MeSH Terms: Animals, Aorta, Thoracic, Cells, Cultured, Endocytosis, MAP Kinase Kinase Kinase 5, Mice, Inbred C57BL, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, NADPH Oxidase 1, Receptors, Tumor Necrosis Factor, Type I, Signal Transduction, Superoxides, Tumor Necrosis Factor-alpha
Added April 3, 2019
0 Communities
1 Members
0 Resources
13 MeSH Terms
CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments.
Farhang N, Brunger JM, Stover JD, Thakore PI, Lawrence B, Guilak F, Gersbach CA, Setton LA, Bowles RD
(2017) Tissue Eng Part A 23: 738-749
MeSH Terms: Adipose Tissue, Cell Differentiation, Cell Survival, Chondrogenesis, Clustered Regularly Interspaced Short Palindromic Repeats, DNA, Epigenesis, Genetic, Extracellular Matrix, Gene Editing, Glycosaminoglycans, HEK293 Cells, Humans, Immunomodulation, Inflammation, Lentivirus, NF-kappa B, Receptors, Cytokine, Receptors, Tumor Necrosis Factor, Stem Cells, Tissue Engineering, Transduction, Genetic
Added March 16, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
LRRC8A channels support TNFα-induced superoxide production by Nox1 which is required for receptor endocytosis.
Choi H, Ettinger N, Rohrbough J, Dikalova A, Nguyen HN, Lamb FS
(2016) Free Radic Biol Med 101: 413-423
MeSH Terms: Cell Line, Cyclopentanes, Endocytosis, Gene Expression Regulation, HEK293 Cells, Humans, Indans, JNK Mitogen-Activated Protein Kinases, Membrane Proteins, Myocytes, Smooth Muscle, NADPH Oxidase 1, NF-kappa B, Phosphorylation, Protein Subunits, RNA, Small Interfering, Receptors, Tumor Necrosis Factor, Type I, Signal Transduction, Superoxide Dismutase, Superoxides, Tumor Necrosis Factor-alpha, Vascular Cell Adhesion Molecule-1
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Staphylococcus aureus protein A enhances osteoclastogenesis via TNFR1 and EGFR signaling.
Mendoza Bertelli A, Delpino MV, Lattar S, Giai C, Llana MN, Sanjuan N, Cassat JE, Sordelli D, Gómez MI
(2016) Biochim Biophys Acta 1862: 1975-83
MeSH Terms: Animals, Cell Differentiation, ErbB Receptors, Humans, Mice, Mice, Inbred BALB C, Mice, Knockout, Osteoclasts, Osteomyelitis, RANK Ligand, Receptors, Tumor Necrosis Factor, Type I, Staphylococcal Infections, Staphylococcal Protein A, Staphylococcus aureus, Tumor Necrosis Factor-alpha
Added April 3, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
Combining an Aurora Kinase Inhibitor and a Death Receptor Ligand/Agonist Antibody Triggers Apoptosis in Melanoma Cells and Prevents Tumor Growth in Preclinical Mouse Models.
Liu Y, Hawkins OE, Vilgelm AE, Pawlikowski JS, Ecsedy JA, Sosman JA, Kelley MC, Richmond A
(2015) Clin Cancer Res 21: 5338-48
MeSH Terms: Animals, Antibodies, Monoclonal, Antineoplastic Agents, Apoptosis, Aurora Kinases, Azepines, Caspases, Cell Line, Tumor, Cellular Senescence, Disease Models, Animal, Drug Evaluation, Preclinical, Female, Humans, Melanoma, Mice, Protein Kinase Inhibitors, Pyrimidines, Receptors, Death Domain, Receptors, TNF-Related Apoptosis-Inducing Ligand, Receptors, Tumor Necrosis Factor, Member 10c, Signal Transduction, TNF-Related Apoptosis-Inducing Ligand, Tumor Suppressor Protein p53, Xenograft Model Antitumor Assays
Added August 21, 2015
2 Communities
3 Members
0 Resources
24 MeSH Terms
Tumor Necrosis Factor Receptor 2 Restricts the Pathogenicity of CD8(+) T Cells in Mice With Colitis.
Punit S, Dubé PE, Liu CY, Girish N, Washington MK, Polk DB
(2015) Gastroenterology 149: 993-1005.e2
MeSH Terms: Adoptive Transfer, Animals, CD8-Positive T-Lymphocytes, Cell Proliferation, Colitis, Colon, DNA-Binding Proteins, Disease Models, Animal, Gene Expression Regulation, Immunity, Cellular, Interleukin-10, Lymphocyte Activation, Male, Mice, Inbred C57BL, Mice, Knockout, Receptors, Tumor Necrosis Factor, Type II, Signal Transduction, Time Factors
Added April 12, 2016
0 Communities
1 Members
0 Resources
18 MeSH Terms
c-Jun N-terminal kinase attenuates TNFα signaling by reducing Nox1-dependent endosomal ROS production in vascular smooth muscle cells.
Choi H, Dikalova A, Stark RJ, Lamb FS
(2015) Free Radic Biol Med 86: 219-27
MeSH Terms: Animals, Cells, Cultured, Endocytosis, Endosomes, JNK Mitogen-Activated Protein Kinases, Mice, Inbred C57BL, Mice, Knockout, Mitogen-Activated Protein Kinases, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, NADH, NADPH Oxidoreductases, NADPH Oxidase 1, NF-kappa B, Reactive Oxygen Species, Receptors, Tumor Necrosis Factor, Type I, Receptors, Tumor Necrosis Factor, Type II, Signal Transduction, Tumor Necrosis Factor-alpha
Added July 28, 2015
0 Communities
2 Members
0 Resources
18 MeSH Terms
DNA methyltransferase 3a and mitogen-activated protein kinase signaling regulate the expression of fibroblast growth factor-inducible 14 (Fn14) during denervation-induced skeletal muscle atrophy.
Tajrishi MM, Shin J, Hetman M, Kumar A
(2014) J Biol Chem 289: 19985-99
MeSH Terms: Animals, Base Sequence, Conserved Sequence, CpG Islands, DNA, DNA (Cytosine-5-)-Methyltransferases, DNA Methylation, DNA Methyltransferase 3A, Gene Expression, Gene Knockdown Techniques, MAP Kinase Signaling System, Mice, Mice, Inbred C57BL, Models, Biological, Molecular Sequence Data, Muscle Denervation, Muscle, Skeletal, Muscular Atrophy, Promoter Regions, Genetic, RNA, Small Interfering, Receptors, Tumor Necrosis Factor, Sequence Homology, Nucleic Acid, Sp1 Transcription Factor, TWEAK Receptor, Transcription Factor AP-1
Added October 30, 2014
0 Communities
1 Members
0 Resources
25 MeSH Terms
The effects of stress at work and at home on inflammation and endothelial dysfunction.
Non AL, Rimm EB, Kawachi I, Rewak MA, Kubzansky LD
(2014) PLoS One 9: e94474
MeSH Terms: Aged, Biomarkers, Endothelium, Vascular, Health Personnel, Humans, Inflammation, Intercellular Adhesion Molecule-1, Interleukin-6, Life Change Events, Male, Middle Aged, Receptors, Tumor Necrosis Factor, Stress, Psychological, Vascular Cell Adhesion Molecule-1, Workload
Added January 20, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Loss of glutathione peroxidase 7 promotes TNF-α-induced NF-κB activation in Barrett's carcinogenesis.
Peng DF, Hu TL, Soutto M, Belkhiri A, El-Rifai W
(2014) Carcinogenesis 35: 1620-8
MeSH Terms: Adenocarcinoma, Barrett Esophagus, Blotting, Western, Cell Transformation, Neoplastic, Cells, Cultured, Esophageal Neoplasms, Fluorescent Antibody Technique, Glutathione Peroxidase, Humans, NF-kappa B, Peroxidases, RNA, Messenger, RNA, Small Interfering, Reactive Oxygen Species, Real-Time Polymerase Chain Reaction, Receptors, Tumor Necrosis Factor, Type I, Receptors, Tumor Necrosis Factor, Type II, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, Tumor Necrosis Factor-alpha
Added May 29, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms