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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 45

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mPGES-1-Mediated Production of PGE and EP4 Receptor Sensing Regulate T Cell Colonic Inflammation.
Maseda D, Banerjee A, Johnson EM, Washington MK, Kim H, Lau KS, Crofford LJ
(2018) Front Immunol 9: 2954
MeSH Terms: Animals, CD4-Positive T-Lymphocytes, Colitis, Dinoprostone, Intestinal Mucosa, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Nuclear Receptor Subfamily 1, Group F, Member 3, Prostaglandin-E Synthases, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Prostaglandin E, EP4 Subtype, T-Lymphocytes, T-Lymphocytes, Regulatory
Added March 25, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
mPGES1-Dependent Prostaglandin E (PGE) Controls Antigen-Specific Th17 and Th1 Responses by Regulating T Autocrine and Paracrine PGE Production.
Maseda D, Johnson EM, Nyhoff LE, Baron B, Kojima F, Wilhelm AJ, Ward MR, Woodward JG, Brand DD, Crofford LJ
(2018) J Immunol 200: 725-736
MeSH Terms: Animals, Autocrine Communication, Dinoprostone, Epitopes, T-Lymphocyte, Gene Expression Regulation, Immunization, Immunomodulation, Lymphocyte Activation, Mice, Paracrine Communication, Phenotype, Prostaglandin-E Synthases, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Prostaglandin E, EP4 Subtype, Th1 Cells, Th17 Cells
Added March 25, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Efferocytosis-induced prostaglandin E2 production impairs alveolar macrophage effector functions during Streptococcus pneumoniae infection.
Salina AC, Souza TP, Serezani CH, Medeiros AI
(2017) Innate Immun 23: 219-227
MeSH Terms: Animals, Apoptosis, Bacteriolysis, Cyclic AMP, Cyclic AMP-Dependent Protein Kinases, Dinoprostone, Female, Homeostasis, Humans, Hydrogen Peroxide, Jurkat Cells, Macrophages, Alveolar, Phagocytosis, Pneumococcal Infections, Rats, Rats, Wistar, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Prostaglandin E, EP4 Subtype, Signal Transduction, Streptococcus pneumoniae
Added May 4, 2017
0 Communities
1 Members
0 Resources
20 MeSH Terms
Opposing roles of LTB4 and PGE2 in regulating the inflammasome-dependent scorpion venom-induced mortality.
Zoccal KF, Sorgi CA, Hori JI, Paula-Silva FW, Arantes EC, Serezani CH, Zamboni DS, Faccioli LH
(2016) Nat Commun 7: 10760
MeSH Terms: Animals, Arachidonate 5-Lipoxygenase, Blotting, Western, Carrier Proteins, Celecoxib, Cyclic AMP, Cyclic AMP-Dependent Protein Kinases, Cyclooxygenase Inhibitors, Dinoprostone, In Vitro Techniques, Indoles, Indomethacin, Inflammasomes, Interleukin-1beta, Leukotriene B4, Lipoxygenase Inhibitors, Macrophages, Macrophages, Peritoneal, Mice, Mice, Knockout, NF-kappa B, NLR Family, Pyrin Domain-Containing 3 Protein, Phosphoproteins, Prostaglandin Antagonists, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Prostaglandin E, EP4 Subtype, Reverse Transcriptase Polymerase Chain Reaction, Scorpion Stings, Scorpion Venoms, Scorpions, Xanthones
Added May 4, 2017
0 Communities
1 Members
0 Resources
31 MeSH Terms
EP4 and EP2 receptor activation of protein kinase A by prostaglandin E2 impairs macrophage phagocytosis of Clostridium sordellii.
Rogers LM, Thelen T, Fordyce K, Bourdonnay E, Lewis C, Yu H, Zhang J, Xie J, Serezani CH, Peters-Golden M, Aronoff DM
(2014) Am J Reprod Immunol 71: 34-43
MeSH Terms: Cell Line, Clostridium Infections, Clostridium sordellii, Cyclic AMP, Cyclic AMP-Dependent Protein Kinases, Dinoprostone, Humans, Immune Tolerance, Immunity, Innate, Macrophages, Phagocytosis, Protein Isoforms, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Prostaglandin E, EP4 Subtype
Added May 4, 2017
0 Communities
1 Members
0 Resources
14 MeSH Terms
An important role of prostanoid receptor EP2 in host resistance to Mycobacterium tuberculosis infection in mice.
Kaul V, Bhattacharya D, Singh Y, Van Kaer L, Peters-Golden M, Bishai WR, Das G
(2012) J Infect Dis 206: 1816-25
MeSH Terms: Animals, CD4-Positive T-Lymphocytes, Disease Models, Animal, Forkhead Transcription Factors, Gene Expression, Gene Expression Profiling, Immunophenotyping, Interleukin-2 Receptor alpha Subunit, Mice, Mice, Inbred C57BL, Mycobacterium tuberculosis, Receptors, Prostaglandin E, EP2 Subtype, T-Lymphocytes, Regulatory, Tuberculosis
Added March 20, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Prostaglandin E2 deficiency uncovers a dominant role for thromboxane A2 in house dust mite-induced allergic pulmonary inflammation.
Liu T, Laidlaw TM, Feng C, Xing W, Shen S, Milne GL, Boyce JA
(2012) Proc Natl Acad Sci U S A 109: 12692-7
MeSH Terms: Allergens, Animals, Antigens, Dermatophagoides, Asthma, Dinoprostone, Intercellular Adhesion Molecule-1, Intramolecular Oxidoreductases, Male, Mice, Mice, Knockout, Pneumonia, Prostaglandin-E Synthases, Pulmonary Eosinophilia, Receptors, Prostaglandin E, EP1 Subtype, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Thromboxane, Signal Transduction, Thromboxane A2, Up-Regulation
Added March 26, 2014
1 Communities
1 Members
0 Resources
19 MeSH Terms
Prostanoid receptor 2 signaling protects T helper 2 cells from BALB/c mice against activation-induced cell death.
Kaul V, Van Kaer L, Das G, Das J
(2012) J Biol Chem 287: 25434-9
MeSH Terms: Animals, Cell Death, Cell Survival, Dinoprostone, Female, Lymphocyte Activation, Mice, Mice, Inbred BALB C, Prostaglandin Endoperoxides, Receptors, Prostaglandin E, EP2 Subtype, Signal Transduction, Th2 Cells
Added March 20, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
A study of prostaglandin pathway genes and interactions with current nonsteroidal anti-inflammatory drug use in colorectal adenoma.
Edwards TL, Shrubsole MJ, Cai Q, Li G, Dai Q, Rex DK, Ulbright TM, Fu Z, Murff HJ, Smalley W, Ness R, Zheng W
(2012) Cancer Prev Res (Phila) 5: 855-63
MeSH Terms: Adenoma, Aged, Anti-Inflammatory Agents, Non-Steroidal, Case-Control Studies, Colonic Polyps, Colorectal Neoplasms, Cyclooxygenase 2, Female, Genotyping Techniques, Humans, Hydroxyprostaglandin Dehydrogenases, Male, Middle Aged, Polymorphism, Single Nucleotide, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Prostaglandin E, EP3 Subtype, Receptors, Prostaglandin E, EP4 Subtype, Risk Factors, Signal Transduction
Added March 5, 2014
0 Communities
5 Members
0 Resources
19 MeSH Terms
PTEN directly activates the actin depolymerization factor cofilin-1 during PGE2-mediated inhibition of phagocytosis of fungi.
Serezani CH, Kane S, Medeiros AI, Cornett AM, Kim SH, Marques MM, Lee SP, Lewis C, Bourdonnay E, Ballinger MN, White ES, Peters-Golden M
(2012) Sci Signal 5: ra12
MeSH Terms: Actins, Animals, Candida albicans, Candidiasis, Cells, Cultured, Cofilin 1, Cyclic AMP, Cyclic AMP-Dependent Protein Kinase Type I, Cyclic AMP-Dependent Protein Kinase Type II, Dinoprostone, Female, Immune Tolerance, Macrophages, Alveolar, PTEN Phosphohydrolase, Phagocytosis, Phosphorylation, Rats, Rats, Wistar, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Prostaglandin E, EP4 Subtype
Added May 4, 2017
0 Communities
1 Members
0 Resources
20 MeSH Terms