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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 104

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GABA interneurons are the cellular trigger for ketamine's rapid antidepressant actions.
Gerhard DM, Pothula S, Liu RJ, Wu M, Li XY, Girgenti MJ, Taylor SR, Duman CH, Delpire E, Picciotto M, Wohleb ES, Duman RS
(2020) J Clin Invest 130: 1336-1349
MeSH Terms: Animals, Antidepressive Agents, Female, GABAergic Neurons, Gene Knockout Techniques, Glutamate Decarboxylase, Interneurons, Ketamine, Male, Mice, Mice, Transgenic, Parvalbumins, Receptors, N-Methyl-D-Aspartate, Sex Characteristics, Somatostatin
Added March 18, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Agmatine preferentially antagonizes GluN2B-containing N-methyl-d-aspartate receptors in spinal cord.
Waataja JJ, Peterson CD, Verma H, Goracke-Postle CJ, Séguéla P, Delpire E, Wilcox GL, Fairbanks CA
(2019) J Neurophysiol 121: 662-671
MeSH Terms: Agmatine, Animals, Excitatory Amino Acid Agonists, Excitatory Amino Acid Antagonists, Excitatory Postsynaptic Potentials, Male, Mice, Mice, Inbred C57BL, Nociception, Piperidines, Receptors, N-Methyl-D-Aspartate, Sensory Receptor Cells, Spinal Cord Dorsal Horn
Added April 2, 2019
0 Communities
1 Members
0 Resources
13 MeSH Terms
Genetic loss of GluN2B in D1-expressing cell types enhances long-term cocaine reward and potentiation of thalamo-accumbens synapses.
Joffe ME, Turner BD, Delpire E, Grueter BA
(2018) Neuropsychopharmacology 43: 2383-2389
MeSH Terms: Animals, Cocaine, Gene Deletion, Locomotion, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Nucleus Accumbens, Receptors, Dopamine D1, Receptors, N-Methyl-D-Aspartate, Reward, Thalamus
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.
Regan MC, Grant T, McDaniel MJ, Karakas E, Zhang J, Traynelis SF, Grigorieff N, Furukawa H
(2018) Neuron 98: 521-529.e3
MeSH Terms: Animals, Cell Line, Female, HEK293 Cells, Humans, Insecta, Protein Splicing, Protein Structure, Secondary, Protein Structure, Tertiary, Receptors, N-Methyl-D-Aspartate, Xenopus laevis
Added April 10, 2019
0 Communities
1 Members
0 Resources
11 MeSH Terms
Contextual Fear Extinction Induces Hippocampal Metaplasticity Mediated by Metabotropic Glutamate Receptor 5.
Stansley BJ, Fisher NM, Gogliotti RG, Lindsley CW, Conn PJ, Niswender CM
(2018) Cereb Cortex 28: 4291-4304
MeSH Terms: Animals, Extinction, Psychological, Fear, Hippocampus, Long-Term Potentiation, Long-Term Synaptic Depression, Male, Methyl-CpG-Binding Protein 2, Mice, Inbred C57BL, Mice, Transgenic, Receptor, Cannabinoid, CB1, Receptors, Kainic Acid, Receptors, N-Methyl-D-Aspartate
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Role of mGlu Receptors and Inhibitory Neurotransmission in M Dependent Muscarinic LTD in the Prefrontal Cortex: Implications in Schizophrenia.
Ghoshal A, Moran SP, Dickerson JW, Joffe ME, Grueter BA, Xiang Z, Lindsley CW, Rook JM, Conn PJ
(2017) ACS Chem Neurosci 8: 2254-2265
MeSH Terms: Animals, Antipsychotic Agents, Cholinergic Agents, Cognition, Mice, Inbred C57BL, Neuronal Plasticity, Phencyclidine, Prefrontal Cortex, Receptor, Metabotropic Glutamate 5, Receptors, N-Methyl-D-Aspartate, Schizophrenia, Synaptic Transmission
Added March 21, 2018
0 Communities
1 Members
0 Resources
12 MeSH Terms
A Novel Human Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.
Stephenson JR, Wang X, Perfitt TL, Parrish WP, Shonesy BC, Marks CR, Mortlock DP, Nakagawa T, Sutcliffe JS, Colbran RJ
(2017) J Neurosci 37: 2216-2233
MeSH Terms: Animals, Autism Spectrum Disorder, Brain, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Cells, Cultured, Cycloheximide, Dendrites, Disease Models, Animal, Embryo, Mammalian, Excitatory Postsynaptic Potentials, Exploratory Behavior, Female, Gene Expression Regulation, Humans, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Mutation, Rats, Rats, Sprague-Dawley, Receptors, AMPA, Receptors, N-Methyl-D-Aspartate, Sialoglycoproteins, Synaptic Transmission
Added February 2, 2017
1 Communities
2 Members
1 Resources
25 MeSH Terms
Reduced ethanol drinking following selective cortical interneuron deletion of the GluN2B NMDA receptors subunit.
Radke AK, Jury NJ, Delpire E, Nakazawa K, Holmes A
(2017) Alcohol 58: 47-51
MeSH Terms: Alcohol Drinking, Animals, Cerebral Cortex, Choice Behavior, Ethanol, Female, Gene Deletion, Interneurons, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Protein Subunits, Receptors, N-Methyl-D-Aspartate
Added May 3, 2017
0 Communities
1 Members
0 Resources
15 MeSH Terms
CaMKII-mediated phosphorylation of GluN2B regulates recombinant NMDA receptor currents in a chloride-dependent manner.
Tavalin SJ, Colbran RJ
(2017) Mol Cell Neurosci 79: 45-52
MeSH Terms: Action Potentials, Calcium Signaling, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Chlorides, HEK293 Cells, Humans, Phosphorylation, Protein Binding, Protein Processing, Post-Translational, Receptors, N-Methyl-D-Aspartate
Added April 26, 2017
0 Communities
1 Members
0 Resources
10 MeSH Terms
Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Romero-Hernandez A, Simorowski N, Karakas E, Furukawa H
(2016) Neuron 92: 1324-1336
MeSH Terms: 2-Hydroxyphenethylamine, Animals, Binding Sites, Blotting, Western, Crystallography, Hydrogen Bonding, Piperidines, Protein Structure, Quaternary, Receptors, N-Methyl-D-Aspartate, Sf9 Cells, Spodoptera, Xenopus laevis, Zinc
Added April 3, 2018
0 Communities
1 Members
0 Resources
MeSH Terms